| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| January 6th, 2006 | 21 | No |
Popular Name: 2-[(2-bromophenyl)methylene]-6-methoxy-tetralin-1-one 2-[(2-bromophenyl)methylene]-6-m…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 4.87 | 1.15 | -8.83 | 0 | 2 | 0 | 26 | 343.22 | 2 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CP27A-1-E | Sterol 26-hydroxylase, Mitochondrial (cluster #1 Of 1), Eukaryotic | Eukaryotes | 4330 | 0.36 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| CP27A_HUMAN | Q02318 | Sterol 26-hydroxylase, Mitochondrial, Human | 4330 | 0.36 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Endogenous sterols | |
| Synthesis of bile acids and bile salts via 24-hydroxycholesterol | |
| Synthesis of bile acids and bile salts via 27-hydroxycholesterol | |
| Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol |
