| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 24th, 2004 | 16 | Yes |
Popular Name: DNC005896 DNC005896
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.86 | 3.8 | -11.25 | 3 | 3 | 0 | 59 | 214.268 | 1 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SIRT1-1-E | NAD-dependent Deacetylase Sirtuin 1 (cluster #1 Of 3), Eukaryotic | Eukaryotes | 3300 | 0.48 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| SIRT1_HUMAN | Q96EB6 | NAD-dependent Deacetylase Sirtuin 1, Human | 1470 | 0.51 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Regulation of HSF1-mediated heat shock response | |
| SIRT1 negatively regulates rRNA Expression |
