In ZINC since | Heavy atoms | Benign functionality |
---|---|---|
July 24th, 2004 | 30 | Yes |
5-Hydroxy-3-(4-hydroxy-phenyl)-8,8-dimethyl-6-(3-methyl-but-2-enyl)-8H-pyrano[2,3-f]chromen-4-one
Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
---|---|---|---|---|---|---|---|---|---|---|
Ref Reference (pH 7) | 5.73 | 9.29 | -12.67 | 2 | 5 | 0 | 80 | 404.462 | 3 | ↓ |
Note Type | Comments | Provided By |
---|---|---|
biological_source | Isol. from fruit of Maclura pomifera (osage orange) root, Derris scandens, Erythrina variegata and Euchresta spp. | ZereneX Building Blocks |
biological_use | Cytostatic | IBScreen Bioactives |
PUBCHEM_PATENT_ID | EP0126991A1; EP0742012A2; US4539230; WO2000045165A1 | IBM Patent Data |
mechanism | Inhibits proliferation of murine leukemia cells (L1210/0) and human T-lymphocyte cells | IBScreen Bioactives |