| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| February 2nd, 2006 | 7 | No |
Popular Name: 2-Amino-4-methylthiazole 2-Amino-4-methylthiazole
Find On: PubMed — Wikipedia — Google
CAS Numbers: 1603-91-4 , 1603914 , 6142-15-0 , [1603-91-4] , [6142-15-0]
"2-Amino-4-methylthiazole, 98%"
2-Amino-4-(methyl-d3)-thiazole
2-AMino-4-Methylthiazole Hydrochloride
2-Amino-4-methylthiazole, 98+%
2-Amino-4-MethylthiazoleHydrochloride
2-thiazolamine, 4-methyl-, monohydrobromide
4-methyl-1,3-thiazol-2-amine hydrobromide
4-methyl-1,3-thiazol-2-amine hydrochloride
4-Methyl-thiazol-2-ylamine hydrochloride
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.70 | 1.22 | -5.3 | 2 | 2 | 0 | 39 | 114.173 | 0 | ↓ |
| Lo Low (pH 4.5-6) | 0.70 | 1.68 | -25.61 | 3 | 2 | 1 | 40 | 115.181 | 0 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| MP | 173 | TCI |
| BP [°C] | 231 - 232 | Acros Organics |
| BP | 231-232° | Oakwood Chemical |
| Boiling_Point | 231-233? | Alfa-Aesar |
| Boiling_Point | 231-233° | Alfa-Aesar |
| BP | 232 | TCI |
| Mp [°C] | 42 - 47 | Acros Organics |
| Melting_Point | 42-46? | Alfa-Aesar |
| Melting_Point | 42-46° | Alfa-Aesar |
| MP | 44 - 47 | Enamine Building Blocks |
| MP | 44-47° | Fluorochem |
| MP | 44...47 | Enamine Building Blocks |
| MP | 45 | TCI |
| purity | 9.500000000000000e+001 | Enamine Building Blocks Enamine Building Blocks |
| Purity | 95+% | Matrix Scientific |
| Purity | 98% | Fluorochem |
| Purity | 99% | Fluorochem |
| H phrase | H315: Causes skin irritation | Acros Organics |
| H phrase | H315: Causes skin irritation; H319: Causes serious eye irritation; H335: May cause respiratory irritation; H302: Harmful if swallowed | Acros Organics |
| Warnings | IRRITANT | Matrix Scientific |
| P phrase | P301+ P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell | Acros Organics |
| P phrase | P301+ P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell; P302+ P352: IF ON SKIN: Wash with plenty of soap and water; P280: Wear protective gloves/protective clothing/eye protection/face protection; P305 + P351 + P338: IF IN E | Acros Organics |
| R phrase | R22: Harmful if swallowed. | Acros Organics |
| R phrase | R22: Harmful if swallowed.; R36/37/38: Irritating to eyes, respiratory system and skin. | Acros Organics |
| S phrase | S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. | Acros Organics |
| S phrase | S26: In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.; S37/39: Wear suitable gloves and eye/face protection. | Acros Organics |
| Hazard | XN: Harmful | Acros Organics |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NOS1-7-E | Nitric-oxide Synthase, Brain (cluster #7 Of 7), Eukaryotic | Eukaryotes | 10000 | 1.00 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| NOS1_HUMAN | P29475 | Nitric-oxide Synthase, Brain, Human | 10000 | 1.00 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Nitric oxide stimulates guanylate cyclase | |
| Phagosomal maturation (early endosomal stage) |
