| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| December 14th, 2010 | 28 | Yes |
Popular Name: 2-ethyl-8-[(2R)-2-(1-oxoisoindolin-2-yl)butanoyl]-1,3,8-triazaspiro[4.5]dec-1-en-4-one 2-ethyl-8-[(2R)-2-(1-oxoisoindol…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 1.41 | 7.86 | -30.89 | 1 | 7 | 0 | 82 | 382.464 | 4 | ↓ |
| Lo Low (pH 4.5-6) | 1.41 | 8.55 | -57.14 | 2 | 7 | 1 | 84 | 383.472 | 4 | ↓ |
No pre-computed analogs available. Try a structural similarity search.
![1,3,8-triazaspiro[4.5]dec-2-en-4-one](http://zinc12.docking.org/img/rings/373583.gif)
![8-[2-(1-ketoisoindolin-2-yl)acetyl]-2,4,8-triazaspiro[4.5]dec-2-en-1-one](http://zinc12.docking.org/img/rings/409295.gif)