| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 29th, 2005 | 32 | Yes |
Popular Name: Prulifloxacin Prulifloxacin
Find On: PubMed — Wikipedia — Google
CAS Numbers: 123447-62-1 , 5875-06-9
None
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 0.16 | 13.14 | -120.41 | 1 | 9 | 0 | 113 | 461.471 | 4 | ↓ |
| Mid Mid (pH 6-8) | 0.16 | 10.91 | -73.82 | 0 | 9 | -1 | 112 | 460.463 | 4 | ↓ |
| Lo Low (pH 4.5-6) | -2.58 | 11.23 | -102.6 | 2 | 9 | 1 | 116 | 462.479 | 3 | ↓ |
| Note Type | Comments | Provided By |
|---|---|---|
| biological_use | Antibacterial agent | IBScreen Bioactives IBScreen Bioactives |
| biological_use | Antiseptic | IBScreen Bioactives |
| mechanism | Blocker of bacterial DNA replication | IBScreen Bioactives IBScreen Bioactives |
| mechanism | Interference with DNA gyrase (supercoiling | IBScreen Bioactives |
| biological_use | Prodrug | IBScreen Bioactives |
| mechanism | reestablishment of DNA coil integrity during replication) | IBScreen Bioactives |
