| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| November 1st, 2011 | 24 | Yes |
Popular Name: (3S)-1-(2-fluorophenyl)-3-[(3R)-3-hydroxy-3-(trifluoromethyl)-1-piperidyl]pyrrolidin-2-one (3S)-1-(2-fluorophenyl)-3-[(3R)-…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 2.38 | 6.68 | -39.11 | 2 | 4 | 1 | 45 | 347.332 | 3 | ↓ |
| Hi High (pH 8-9.5) | 2.38 | 4.44 | -11.6 | 1 | 4 | 0 | 44 | 346.324 | 3 | ↓ |
| Hi High (pH 8-9.5) | 2.38 | 4.96 | -48.4 | 0 | 4 | -1 | 47 | 345.316 | 3 | ↓ |
No pre-computed analogs available. Try a structural similarity search.
