| In ZINC since | Heavy atoms | Benign functionality |
|---|---|---|
| July 26th, 2004 | 26 | Yes |
Popular Name: N-[4-[(2-chlorobenzoyl)amino]-3-methoxy-phenyl]-2-furamide N-[4-[(2-chlorobenzoyl)amino]-3-…
| Type pH range | xlogP | Des A‑Pol Apolar desolvation (kcal/mol) | Des Pol Polar desolvation (kcal/mol) | H Don H-bond donors | H Acc H-bond acceptors | Chg Net charge | tPSA (Ų) | MWT Molecular weight (g/mol) | RB Rotatable bonds | DL |
|---|---|---|---|---|---|---|---|---|---|---|
| Ref Reference (pH 7) | 3.59 | 6.47 | -16.84 | 2 | 6 | 0 | 81 | 370.792 | 5 | ↓ |
| Code | Description | Organism Class | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM4-2-E | Metabotropic Glutamate Receptor 4 (cluster #2 Of 3), Eukaryotic | Eukaryotes | 977 | 0.32 | Binding ≤ 10μM |
| Uniprot | Swissprot | Description | Affinity (nM) | LE (kcal/mol/atom) | Type |
|---|---|---|---|---|---|
| GRM4_HUMAN | Q14833 | Metabotropic Glutamate Receptor 4, Human | 977 | 0.32 | Binding ≤ 1μM |
| GRM4_HUMAN | Q14833 | Metabotropic Glutamate Receptor 4, Human | 977 | 0.32 | Binding ≤ 10μM |
| GRM4_RAT | P31423 | Metabotropic Glutamate Receptor 4, Rat | 1010 | 0.32 | Binding ≤ 10μM |
| Description | Species |
|---|---|
| Class C/3 (Metabotropic glutamate/pheromone receptors) | |
| G alpha (i) signalling events |
