UCSF

ZINC08234358

Substance Information

In ZINC since Heavy atoms Benign functionality
July 5th, 2006 25 No

CAS Number: 22910-60-7

Download: MOL2 SDF SMILES Flexibase

Physical Representations

Type pH range xlogP Des A‑Pol Apolar desolvation (kcal/mol) Des Pol Polar desolvation (kcal/mol) H Don H-bond donors H Acc H-bond acceptors Chg Net charge tPSA (Ų) MWT Molecular weight (g/mol) RB Rotatable bonds DL
Ref Reference (pH 7) 8.34 1.01 -57.84 1 3 -1 60 345.503 14

Activity (Go SEA)

Clustered Target Annotations
Code Description Organism Class Affinity (nM) LE (kcal/mol/atom) Type
PLCG1-1-E Phospholipase C-gamma-1 (cluster #1 Of 1), Eukaryotic Eukaryotes 5660 0.29 Binding ≤ 10μM
ChEMBL Target Annotations
Uniprot Swissprot Description Affinity (nM) LE (kcal/mol/atom) Type
PLCG1_BOVIN P08487 1-phosphatidylinositol-4,5-bisphosphate Phosphodiesterase Gamma-1, Bovin 5660 0.29 Binding ≤ 10μM

Analogs ( Draw Identity 99% 90% 80% 70% )