UCSF

3-beta-hydroxysteroid Dehydrogenase Type VII, Human (116 Compounds)

Swissprot:
3BHS7_HUMAN
Stitch:
3BHS7_HUMAN
UniProt:
Q9H2F3
ChEMBL:
CHEMBL3600
Reactome:
REACT_11053
REACT_11048
REACT_11041
PDB:
HSD3B7

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 116 3 1 1
Binding ≤ 1μM 80 3 1 1

Reactome Network (3)

Reactome ID Description Species
REACT_11053 Synthesis of bile acids and bile salts via 24-hydroxycholesterol Homo sapiens
REACT_11048 Synthesis of bile acids and bile salts via 27-hydroxycholesterol Homo sapiens
REACT_11041 Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol Homo sapiens
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
3BHS1_HUMAN P14060 CHEMBL1958 3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type I, Human 387 5 1 1
3BHS2_HUMAN P26439 CHEMBL3670 3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type II, Human 370 5 1 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
3BHS1_HUMAN P14060 CHEMBL1958 3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type I, Human 116
3BHS2_HUMAN P26439 CHEMBL3670 3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type II, Human 116
S5A1_HUMAN P18405 CHEMBL1787 Steroid 5-alpha-reductase 1, Human 116
S5A2_HUMAN P31213 CHEMBL1856 Steroid 5-alpha-reductase 2, Human 116
S5A1_RAT P24008 CHEMBL3422 Steroid 5-alpha-reductase 1, Rat 16
S5A2_RAT P31214 CHEMBL5099 Steroid 5-alpha-reductase 2, Rat 16
3BHS2_RAT P22072 CHEMBL4821 3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type II, Rat 12
3BHS5_RAT P27364 CHEMBL4490 3-beta-hydroxysteroid Dehydrogenase Type III, Rat 12

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