Names
Compounds (544)
Reactome (0)
Related By:
Pathway (0)
Organism (1)
Gene (1)
Org. Clust. (1)
ChEMBL (24)
Rings (38)

Steroid 5-alpha-reductase 1, Rat (544 Compounds)

Swissprot:: S5A1_RAT
Stitch:: S5A1_RAT
UniProt:: P24008
ChEMBL:: CHEMBL3422
PDB:: Srd5a1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	544	27	5	5
Binding ≤ 1μM	505	24	3	3
Functional ≤ 10μM	11	0	0	0

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
S5A1_HUMAN	P18405	CHEMBL1787	Steroid 5-alpha-reductase 1, Human	1,054	14	6	6

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
S5A2_RAT	P31214	CHEMBL5099	Steroid 5-alpha-reductase 2, Rat	541	27	5	5

Clustered By Gene (0)

Clustered By Organism (1)

Code	Description	Substances	Purchasable	Natural	In Man
S5A1-1-E	Steroid 5-alpha-reductase 1 (cluster #1 Of 2), Eukaryotic	823	27	7	9
S5A1-2-E	Steroid 5-alpha-reductase 1 (cluster #2 Of 2), Eukaryotic	759	16	2	1

Uniprot	Swissprot	Chembl	Description	Number Shared
S5A2_RAT	P31214	CHEMBL5099	Steroid 5-alpha-reductase 2, Rat	536
S5A2_HUMAN	P31213	CHEMBL1856	Steroid 5-alpha-reductase 2, Human	98
S5A1_HUMAN	P18405	CHEMBL1787	Steroid 5-alpha-reductase 1, Human	87
3BHS1_HUMAN	P14060	CHEMBL1958	3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type I, Human	20
3BHS2_HUMAN	P26439	CHEMBL3670	3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type II, Human	20
3BHS7_HUMAN	Q9H2F3	CHEMBL3600	3-beta-hydroxysteroid Dehydrogenase Type VII, Human	16
3BHS2_RAT	P22072	CHEMBL4821	3-beta-hydroxysteroid Dehydrogenase/delta 5-->4-isomerase Type II, Rat	13
3BHS5_RAT	P27364	CHEMBL4490	3-beta-hydroxysteroid Dehydrogenase Type III, Rat	13
ANDR_HUMAN	P10275	CHEMBL1871	Androgen Receptor, Human	2
ERG2_YEAST	P32352	CHEMBL3224	C-8 Sterol Isomerase, Yeast	2
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	2
ANDR_MOUSE	P19091	CHEMBL3056	Androgen Receptor, Mouse	1
ANDR_RAT	P15207	CHEMBL3072	Androgen Receptor, Rat	1
CP19A_HUMAN	P11511	CHEMBL1978	Cytochrome P450 19A1, Human	1
ESR1_RAT	P06211	CHEMBL2724	Estrogen Receptor Alpha, Rat	1
ESR2_RAT	Q62986	CHEMBL3021	Estrogen Receptor Beta, Rat	1
FABPL_RAT	P02692	CHEMBL5738	Fatty Acid-binding Protein, Liver, Rat	1
GCR_HUMAN	P04150	CHEMBL2034	Glucocorticoid Receptor, Human	1
MCR_HUMAN	P08235	CHEMBL1994	Mineralocorticoid Receptor, Human	1
PRGR_CHICK	P07812	CHEMBL3304	Progesterone Receptor, Chick	1
PRGR_HUMAN	P06401	CHEMBL208	Progesterone Receptor, Human	1
PRGR_RABIT	P06186	CHEMBL3456	Progesterone Receptor, Rabit	1
SGMR1_CAVPO	Q60492	CHEMBL4153	Sigma-1 Receptor, Guinea Pig	1
SHBG_HUMAN	P04278	CHEMBL3305	Testis-specific Androgen-binding Protein, Human	1