PRGR_HUMAN - Progesterone Receptor, Human | ZINC Is Not Commercial - A database of commercially-available compounds

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	1,336	42	15	10
Binding ≤ 1μM	1,131	33	15	10
Functional ≤ 10μM	1,160	30	17	12

Reactome ID	Description	Species
REACT_15525	Nuclear Receptor transcription pathway	Homo sapiens
REACT_116022	Nuclear signaling by ERBB4	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
ANDR_HUMAN	P10275	CHEMBL1871	Androgen Receptor, Human	525
ESR1_HUMAN	P03372	CHEMBL206	Estrogen Receptor Alpha, Human	52
ESR2_HUMAN	Q92731	CHEMBL242	Estrogen Receptor Beta, Human	45
THA_HUMAN	P10827	CHEMBL1860	Thyroid Hormone Receptor Alpha, Human	2
THB_HUMAN	P10828	CHEMBL1947	Thyroid Hormone Receptor Beta-1, Human	1

Nuclear signaling by ERBB4

Uniprot	Swissprot	Chembl	Description	Number Shared
ESR1_HUMAN	P03372	CHEMBL206	Estrogen Receptor Alpha, Human	52

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
PRGR_CHICK	P07812	CHEMBL3304	Progesterone Receptor, Chick	9	2	1	2
PRGR_RABIT	P06186	CHEMBL3456	Progesterone Receptor, Rabit	93	4	4	4
PRGR_RAT	Q63449	CHEMBL2596	Progesterone Receptor, Rat	16	4	2	3

Clustered By Gene (0)

Clustered By Organism (2)

Code	Description	Substances	Purchasable	Natural	In Man
PRGR-1-E	Progesterone Receptor (cluster #1 Of 3), Eukaryotic	91	23	15	12
PRGR-2-E	Progesterone Receptor (cluster #2 Of 3), Eukaryotic	1,324	26	5	3
PRGR-3-E	Progesterone Receptor (cluster #3 Of 3), Eukaryotic	42	1	0	0

Uniprot	Swissprot	Chembl	Description	Number Shared
GCR_HUMAN	P04150	CHEMBL2034	Glucocorticoid Receptor, Human	722
ANDR_HUMAN	P10275	CHEMBL1871	Androgen Receptor, Human	522
MCR_HUMAN	P08235	CHEMBL1994	Mineralocorticoid Receptor, Human	333
Z80712	Z80712	CHEMBL614361	T47D (Breast Carcinoma Cells)	79
ESR1_HUMAN	P03372	CHEMBL206	Estrogen Receptor Alpha, Human	50
ESR2_HUMAN	Q92731	CHEMBL242	Estrogen Receptor Beta, Human	45
MCR_RAT	P22199	CHEMBL3507	Mineralocorticoid Receptor, Rat	18
Z80110	Z80110	CHEMBL613507	CV-1 (Kidney Cells)	11
PRGR_CHICK	P07812	CHEMBL3304	Progesterone Receptor, Chick	9
GCR_RAT	P06536	CHEMBL3368	Glucocorticoid Receptor, Rat	8
ANDR_MOUSE	P19091	CHEMBL3056	Androgen Receptor, Mouse	5
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	5
NR1I2_HUMAN	O75469	CHEMBL3401	Pregnane X Receptor, Human	5
MMP1_HUMAN	P03956	CHEMBL332	Matrix Metalloproteinase-1, Human	3
Z80243	Z80243	CHEMBL614334	MDA-MB-453 (Breast Adenocarcinoma Cells)	3
ATTY_RAT	P04694	CHEMBL5947	Tyrosine Aminotransferase, Rat	2
ESR1_RAT	P06211	CHEMBL2724	Estrogen Receptor Alpha, Rat	2
ESR2_RAT	Q62986	CHEMBL3021	Estrogen Receptor Beta, Rat	2
GCR_MOUSE	P06537	CHEMBL3144	Glucocorticoid Receptor, Mouse	2
THA_HUMAN	P10827	CHEMBL1860	Thyroid Hormone Receptor Alpha, Human	2
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	2
Z80491	Z80491	CHEMBL614163	SK-N-MC (Neuroepithelioma Cells)	2
Z80951	Z80951	CHEMBL614822	NIH3T3 (Fibroblasts)	2
Z81170	Z81170	CHEMBL612518	LNCaP (Prostate Carcinoma)	2
ANDR_RAT	P15207	CHEMBL3072	Androgen Receptor, Rat	1
ERG2_YEAST	P32352	CHEMBL3224	C-8 Sterol Isomerase, Yeast	1
FABPL_RAT	P02692	CHEMBL5738	Fatty Acid-binding Protein, Liver, Rat	1
GPBAR_HUMAN	Q8TDU6	CHEMBL5409	G-protein Coupled Bile Acid Receptor 1, Human	1
NR1H4_HUMAN	Q96RI1	CHEMBL2047	Bile Acid Receptor FXR, Human	1
NR1H4_MOUSE	Q60641	CHEMBL5343	Bile Acid Receptor, Mouse	1
PRGR_RABIT	P06186	CHEMBL3456	Progesterone Receptor, Rabit	1
PRGR_RAT	Q63449	CHEMBL2596	Progesterone Receptor, Rat	1
S5A1_RAT	P24008	CHEMBL3422	Steroid 5-alpha-reductase 1, Rat	1
S5A2_RAT	P31214	CHEMBL5099	Steroid 5-alpha-reductase 2, Rat	1
SGMR1_CAVPO	Q60492	CHEMBL4153	Sigma-1 Receptor, Guinea Pig	1
SGMR1_HUMAN	Q99720	CHEMBL287	Sigma Opioid Receptor, Human	1
THB_HUMAN	P10828	CHEMBL1947	Thyroid Hormone Receptor Beta-1, Human	1
VP16_HHV11	P06492	CHEMBL4218	Alpha Trans-inducing Protein (VP16), Hhv11	1
Z80453	Z80453	CHEMBL614897	SC-3	1
Z81011	Z81011	CHEMBL614840	Human Cell Lines	1