UCSF

AMP-activated Protein Kinase, Gamma-1 Subunit, Human (14 Compounds)

Swissprot:
AAKG1_HUMAN
Stitch:
AAKG1_HUMAN
UniProt:
P54619
ChEMBL:
CHEMBL2393
Reactome:
REACT_200686
REACT_21285
REACT_21393
REACT_147867
PDB:
2UV4 (DOCK)
2UV5 (DOCK)
2UV6 (DOCK)
2UV7 (DOCK)
PRKAG1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 14 2 0 1
Binding ≤ 1μM 6 1 0 1

Reactome Network (4)

Reactome ID Description Species
REACT_200686 Activation of PPARGC1A (PGC-1alpha) by phosphorylation Homo sapiens
REACT_21285 Regulation of AMPK activity via LKB1 Homo sapiens
REACT_21393 Regulation of Rheb GTPase activity by AMPK Homo sapiens
REACT_147867 Translocation of GLUT4 to the plasma membrane Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
AAKB1_HUMAN Q9Y478 CHEMBL3847 AMP-activated Protein Kinase, Beta-1 Subunit, Human 14
AAPK2_HUMAN P54646 CHEMBL2116 AMP-activated Protein Kinase, Alpha-2 Subunit, Human 14

Regulation of AMPK activity via LKB1

Uniprot Swissprot Chembl Description Number Shared
AAKB1_HUMAN Q9Y478 CHEMBL3847 AMP-activated Protein Kinase, Beta-1 Subunit, Human 14
AAPK2_HUMAN P54646 CHEMBL2116 AMP-activated Protein Kinase, Alpha-2 Subunit, Human 14

Regulation of Rheb GTPase activity by AMPK

Uniprot Swissprot Chembl Description Number Shared
AAKB1_HUMAN Q9Y478 CHEMBL3847 AMP-activated Protein Kinase, Beta-1 Subunit, Human 14
AAPK2_HUMAN P54646 CHEMBL2116 AMP-activated Protein Kinase, Alpha-2 Subunit, Human 14

Translocation of GLUT4 to the plasma membrane

Uniprot Swissprot Chembl Description Number Shared
AAKB1_HUMAN Q9Y478 CHEMBL3847 AMP-activated Protein Kinase, Beta-1 Subunit, Human 14
AAPK2_HUMAN P54646 CHEMBL2116 AMP-activated Protein Kinase, Alpha-2 Subunit, Human 14

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
AAKB1_HUMAN Q9Y478 CHEMBL3847 AMP-activated Protein Kinase, Beta-1 Subunit, Human 14
AAPK2_HUMAN P54646 CHEMBL2116 AMP-activated Protein Kinase, Alpha-2 Subunit, Human 14
FLT3_HUMAN P36888 CHEMBL1974 Tyrosine-protein Kinase Receptor FLT3, Human 8
MKNK1_HUMAN Q9BUB5 CHEMBL4718 MAP Kinase-interacting Serine/threonine-protein Kinase MNK1, Human 8
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 8
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 8
EPHA2_HUMAN P29317 CHEMBL2068 Ephrin Type-A Receptor 2, Human 7
KS6A1_HUMAN Q15418 CHEMBL2553 Ribosomal Protein S6 Kinase Alpha 1, Human 7
LCK_HUMAN P06239 CHEMBL258 Tyrosine-protein Kinase LCK, Human 7
VGFR1_HUMAN P17948 CHEMBL1868 Vascular Endothelial Growth Factor Receptor 1, Human 7
BMP4_HUMAN P12644 CHEMBL5350 Bone Morphogenetic Protein 4, Human 2

Most Common Rings