UCSF

Bifunctional Dihydrofolate Reductase-thymidylate Synthase, Trycr (7 Compounds)

Swissprot:
DRTS_TRYCR
Stitch:
DRTS_TRYCR
UniProt:
Q27793
ChEMBL:
CHEMBL1163130
PDB:
2H2Q (DOCK)
3CL9 (DOCK)
3CLB (DOCK)
3HBB (DOCK)
3INV (DOCK)
3IRM (DOCK)
3IRN (DOCK)
3IRO (DOCK)

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 7 1 1 1
Binding ≤ 1μM 7 1 1 1

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
DRTS_PLAFK P13922 CHEMBL1939 Dihydrofolate Reductase, Plafk 184 41 5 7
DRTS_TOXGO Q07422 CHEMBL2425 Dihydrofolate Reductase, Toxgo 539 22 9 17

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
DRTS-1-E Bifunctional Dihydrofolate Reductase-thymidylate Synthase (cluster #1 Of 3), Eukaryotic 638 47 13 22
DRTS-2-E Bifunctional Dihydrofolate Reductase-thymidylate Synthase (cluster #2 Of 3), Eukaryotic 2 2 0 0
DRTS-3-E Bifunctional Dihydrofolate Reductase-thymidylate Synthase (cluster #3 Of 3), Eukaryotic 92 13 1 2
Uniprot Swissprot Chembl Description Number Shared
DYR_HUMAN P00374 CHEMBL202 Dihydrofolate Reductase, Human 7
DRTS_TOXGO Q07422 CHEMBL2425 Dihydrofolate Reductase, Toxgo 1
DYR_CANAX P22906 CHEMBL2329 Dihydrofolate Reductase, Canax 1
DYR_ECOLI P0ABQ4 CHEMBL1809 Dihydrofolate Reductase, Ecoli 1
DYR_MOUSE P00375 CHEMBL4564 Dihydrofolate Reductase, Mouse 1
DYR_PNECA P16184 CHEMBL1926 Dihydrofolate Reductase, Pneca 1
DYR_RAT Q920D2 CHEMBL2363 Dihydrofolate Reductase, Rat 1
DYR_YEAST P07807 CHEMBL2576 Dihydrofolate Reductase, Yeast 1
O30463_MYCAV O30463 CHEMBL5457 Dihydrofolate Reductase, Mycav 1