UCSF

Endothelin Receptor ET-B, Human (820 Compounds)

Swissprot:
EDNRB_HUMAN
Stitch:
EDNRB_HUMAN
UniProt:
P24530
ChEMBL:
CHEMBL1785
Reactome:
REACT_18283
REACT_14819
PDB:
EDNRB

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 820 13 5 9
Binding ≤ 1μM 491 10 4 8
Functional ≤ 10μM 126 5 2 2

Reactome Network (2)

Reactome ID Description Species
REACT_18283 G alpha (q) signalling events Homo sapiens
REACT_14819 Peptide ligand-binding receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
AGTR1_HUMAN P30556 CHEMBL227 Angiotensin II Type 1 Receptor, Human 4
EDNRA_HUMAN P25101 CHEMBL252 Endothelin Receptor ET-A, Human 842

Peptide ligand-binding receptors

Uniprot Swissprot Chembl Description Number Shared
AGTR1_HUMAN P30556 CHEMBL227 Angiotensin II Type 1 Receptor, Human 4
AGTR2_HUMAN P50052 CHEMBL4607 Angiotensin II Type 2 (AT-2) Receptor, Human 2
EDNRA_HUMAN P25101 CHEMBL252 Endothelin Receptor ET-A, Human 842
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
EDNRB_BOVIN P28088 CHEMBL4401 Endothelin Receptor ET-B, Bovin 0 0 0 0
EDNRB_MOUSE P48302 CHEMBL1681617 Endothelin B Receptor, Mouse 4 0 0 0
EDNRB_PIG P35463 CHEMBL3949 Endothelin Receptor ET-B, Pig 491 2 1 3
EDNRB_RAT P21451 CHEMBL4631 Endothelin Receptor ET-B, Rat 102 0 0 0

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
EDNRA_HUMAN P25101 CHEMBL252 Endothelin Receptor ET-A, Human 842
EDNRA_RAT P26684 CHEMBL4566 Endothelin Receptor ET-A, Rat 92
EDNRB_PIG P35463 CHEMBL3949 Endothelin Receptor ET-B, Pig 44
EDNRA_PIG Q29010 CHEMBL4130 Endothelin Receptor ET-A, Pig 29
EDNRB_RAT P21451 CHEMBL4631 Endothelin Receptor ET-B, Rat 9
AGTR1_HUMAN P30556 CHEMBL227 Angiotensin II Type 1 Receptor, Human 4
AGTR2_HUMAN P50052 CHEMBL4607 Angiotensin II Type 2 (AT-2) Receptor, Human 2
EDNRA_MOUSE Q61614 CHEMBL2286 Endothelin Receptor ET-A, Mouse 2
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 2
Z50591 Z50591 CHEMBL613489 Bos Taurus 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1

Most Common Rings