UCSF

Endothelin Receptor ET-A, Rat (905 Compounds)

Swissprot:
EDNRA_RAT
Stitch:
EDNRA_RAT
UniProt:
P26684
ChEMBL:
CHEMBL4566
Reactome:
REACT_263374
REACT_250028
PDB:
Ednra

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 905 11 6 10
Binding ≤ 1μM 719 8 4 9
Functional ≤ 10μM 23 0 1 1

Reactome Network (2)

Reactome ID Description Species
REACT_263374 G alpha (q) signalling events Rattus norvegicus
REACT_250028 Peptide ligand-binding receptors Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
EDNRB_RAT P21451 CHEMBL4631 Endothelin Receptor ET-B, Rat 119

Peptide ligand-binding receptors

Uniprot Swissprot Chembl Description Number Shared
EDNRB_RAT P21451 CHEMBL4631 Endothelin Receptor ET-B, Rat 119
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
EDNRA_HUMAN P25101 CHEMBL252 Endothelin Receptor ET-A, Human 1,225 26 7 11
EDNRA_MOUSE Q61614 CHEMBL2286 Endothelin Receptor ET-A, Mouse 16 2 0 0
EDNRA_PIG Q29010 CHEMBL4130 Endothelin Receptor ET-A, Pig 264 2 1 1

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
EDNRA-1-E Endothelin Receptor ET-A (cluster #1 Of 3), Eukaryotic 1,615 22 3 9
EDNRA-2-E Endothelin Receptor ET-A (cluster #2 Of 3), Eukaryotic 10 0 0 0
EDNRA-3-E Endothelin Receptor ET-A (cluster #3 Of 3), Eukaryotic 711 8 7 9
Uniprot Swissprot Chembl Description Number Shared
EDNRB_PIG P35463 CHEMBL3949 Endothelin Receptor ET-B, Pig 286
EDNRB_RAT P21451 CHEMBL4631 Endothelin Receptor ET-B, Rat 119
EDNRB_HUMAN P24530 CHEMBL1785 Endothelin Receptor ET-B, Human 92
EDNRA_HUMAN P25101 CHEMBL252 Endothelin Receptor ET-A, Human 65
EDNRA_PIG Q29010 CHEMBL4130 Endothelin Receptor ET-A, Pig 11
EDNRA_MOUSE Q61614 CHEMBL2286 Endothelin Receptor ET-A, Mouse 2
DYR_HUMAN P00374 CHEMBL202 Dihydrofolate Reductase, Human 1
Q72874_9HIV1 Q72874 CHEMBL243 Human Immunodeficiency Virus Type 1 Protease, 9hiv1 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1

Most Common Rings