Human Immunodeficiency Virus Type 1 Protease, 9hiv1 (4,810 Compounds)


Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 4,810 37 27 40
Binding ≤ 1μM 4,299 30 25 38
Functional ≤ 10μM 225 2 2 2

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
Q72547_9HIV1 Q72547 CHEMBL247 Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1 2,159 77 25 39
Q77YF8_9HIV1 Q77YF8 CHEMBL3852 Human Immunodeficiency Virus Type 1 REV, 9hiv1 12 0 0 0
Q7ZJM1_9HIV1 Q7ZJM1 CHEMBL3471 Human Immunodeficiency Virus Type 1 Integrase, 9hiv1 464 78 45 16
Q993A8_9HIV1 Q993A8 CHEMBL3022 Envelope Polyprotein GP120, 9hiv1 4 0 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
Q72874-1-V Human Immunodeficiency Virus Type 1 Protease (cluster #1 Of 3), Viral 4,487 36 25 40
Q72874-2-V Human Immunodeficiency Virus Type 1 Protease (cluster #2 Of 3), Viral 330 2 2 1
Q72874-3-V Human Immunodeficiency Virus Type 1 Protease (cluster #3 Of 3), Viral 56 1 1 1
Uniprot Swissprot Chembl Description Number Shared
Q4U254_9ENTO Q4U254 CHEMBL2857 Human Rhinovirus A Protease, 9ento 43
Q72547_9HIV1 Q72547 CHEMBL247 Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1 23
Z50607 Z50607 CHEMBL378 Human Immunodeficiency Virus 1 12
CATE_HUMAN P14091 CHEMBL3092 Cathepsin E, Human 10
Q7ZJM1_9HIV1 Q7ZJM1 CHEMBL3471 Human Immunodeficiency Virus Type 1 Integrase, 9hiv1 9
Z50658 Z50658 CHEMBL380 Human Immunodeficiency Virus 2 9
P88142_9HIV2 P88142 CHEMBL5074 Human Immunodeficiency Virus Type 2 Pol Protein, 9hiv2 8
CATD_HUMAN P07339 CHEMBL2581 Cathepsin D, Human 7
PEPA_HUMAN P00790 CHEMBL3295 Pepsin A, Human 7
RENI_HUMAN P00797 CHEMBL286 Renin, Human 7
PEPA_PIG P00791 CHEMBL2714 Pepsin A, Pig 6
PLM2_PLAFA P46925 CHEMBL4414 Plasmepsin 2, Plafa 4
Z50677 Z50677 CHEMBL613758 Human Immunodeficiency Virus 3
Z80295 Z80295 CHEMBL388 MT4 (Lymphocytes) 3
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 2
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 2
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 2
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 2
AA2BR_HUMAN P29275 CHEMBL255 Adenosine A2b Receptor, Human 2
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 2
B7ZW62_HUMAN B7ZW62 CHEMBL3447 Pepsinogen A5, Human 2
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 2
Q8JXU8_9HEPC Q8JXU8 CHEMBL5375 Hepatitis C Virus NS5B RNA-dependent RNA Polymerase, 9hepc 2
Z50657 Z50657 CHEMBL613744 Feline Immunodeficiency Virus 2
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 1
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 1
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 1
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 1
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 1
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 1
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 1
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 1
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 1
5HT2A_PIG P50129 CHEMBL2490 Serotonin 2a (5-HT2a) Receptor, Pig 1
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 1
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 1
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 1
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 1
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 1
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 1
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 1
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 1
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 1
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 1
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 1
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 1
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 1
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 1
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 1
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 1
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 1
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 1
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 1
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 1
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 1
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 1
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 1
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 1
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 1
ADAM9_HUMAN Q13443 CHEMBL5982 ADAM9, Human 1
AP2S1_RAT P62744 CHEMBL1697667 AP-2 Complex Subunit Sigma, Rat 1
CATB_HUMAN P07858 CHEMBL4072 Cathepsin B, Human 1
CATD_BOVIN P80209 CHEMBL4106 Cathepsin D, Bovin 1
CATL1_HUMAN P07711 CHEMBL3837 Cathepsin L, Human 1
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 1
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 1
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 1
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
DRD2_CHLAE P52702 CHEMBL5456 Dopamine D2 Receptor, Chlae 1
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 1
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 1
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 1
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 1
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 1
DYR_HUMAN P00374 CHEMBL202 Dihydrofolate Reductase, Human 1
EBP_HUMAN Q15125 CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human 1
EDNRA_RAT P26684 CHEMBL4566 Endothelin Receptor ET-A, Rat 1
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 1
F16P1_HUMAN P09467 CHEMBL3975 Fructose-1,6-bisphosphatase, Human 1
F16P1_PIG P00636 CHEMBL2263 Fructose-1,6-bisphosphatase, Pig 1
FACE1_MOUSE Q80W54 CHEMBL1075286 CAAX Prenyl Protease 1 Homolog, Mouse 1
FAS_HUMAN P49327 CHEMBL4158 Fatty Acid Synthase, Human 1
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 1
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 1
KITH_HUMAN P04183 CHEMBL2883 Thymidine Kinase, Cytosolic, Human 1
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 1
MMP1_HUMAN P03956 CHEMBL332 Matrix Metalloproteinase-1, Human 1
MMP2_HUMAN P08253 CHEMBL333 Matrix Metalloproteinase-2, Human 1
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 1
MMP7_HUMAN P09237 CHEMBL4073 Matrix Metalloproteinase 7, Human 1
MMP8_HUMAN P22894 CHEMBL4588 Matrix Metalloproteinase 8, Human 1
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 1
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 1
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 1
PEPC_HUMAN P20142 CHEMBL2136 Pepsinogen C, Human 1
PLM1_PLAFA P39898 CHEMBL4687 Plasmepsin 1, Plafa 1
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 1
Q95WR6_LEIDO Q95WR6 CHEMBL4751 Cysteine Protease, Leido 1
RENI_RAT P08424 CHEMBL2322 Renin, Rat 1
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 1
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 1
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 1
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 1
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 1
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 1
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 1
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 1
SRC_HUMAN P12931 CHEMBL267 Tyrosine-protein Kinase SRC, Human 1
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 1
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 1
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 1
Z80294 Z80294 CHEMBL614184 MT2 (Lymphocytes) 1