UCSF

Sigma 2 Receptor (570 Compounds)

Swissprot:
Z100491
Stitch:
Z100491
UniProt:
Z100491
ChEMBL:
CHEMBL613288

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 570 83 8 9
Binding ≤ 1μM 522 70 7 7
Functional ≤ 10μM 0 0 0 0

Reactome Network (0)

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
Z100491-1-O Sigma 2 Receptor (cluster #1 Of 2), Other 566 84 8 9
Z100491-2-O Sigma 2 Receptor (cluster #2 Of 2), Other 12 5 0 0
Uniprot Swissprot Chembl Description Number Shared
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 400
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 134
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 110
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 66
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 61
EBP_CAVPO Q60490 CHEMBL5525 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Guinea Pig 52
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 33
VACHT_HUMAN Q16572 CHEMBL4767 Vesicular Acetylcholine Transporter, Human 25
SGMR1_MOUSE O55242 CHEMBL3465 Sigma Opioid Receptor, Mouse 23
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 23
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 21
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 20
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 20
OPRK_MOUSE P33534 CHEMBL4329 Kappa Opioid Receptor, Mouse 20
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 20
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 19
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 16
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 16
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 16
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 13
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 12
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 11
OPRK_CAVPO P41144 CHEMBL3952 Kappa Opioid Receptor, Guinea Pig 11
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 8
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 8
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 8
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 7
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 7
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 7
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 7
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 6
NMD3B_RAT Q8VHN2 CHEMBL282 Glutamate [NMDA] Receptor Subunit 3B, Rat 6
NMDE2_RAT Q00960 CHEMBL311 Glutamate [NMDA] Receptor Subunit Epsilon 2, Rat 6
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 6
NMDE4_RAT Q62645 CHEMBL303 Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat 6
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 6
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 5
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 5
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 5
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 5
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 5
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 4
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 4
OPRM_CAVPO P97266 CHEMBL4354 Mu Opioid Receptor, Guinea Pig 4
VACHT_TORCA P81721 CHEMBL3313 Vesicular Acetylcholine Transporter, Torca 4
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 4
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 3
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 3
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 3
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 3
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 3
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 3
EBP_HUMAN Q15125 CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human 3
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 3
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 2
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 2
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 2
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 2
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 2
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 2
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 2
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 2
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 2
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 2
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 2
PCP_HUMAN P42785 CHEMBL2335 Lysosomal Pro-X Carboxypeptidase, Human 2
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 2
SCN1A_RAT P04774 CHEMBL4906 Sodium Channel Protein Type I Alpha Subunit, Rat 2
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 2
SCN2A_RAT P04775 CHEMBL3399 Sodium Channel Protein Type II Alpha Subunit, Rat 2
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 2
SCN3A_RAT P08104 CHEMBL4966 Sodium Channel Protein Type III Alpha Subunit, Rat 2
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 2
SCN8A_RAT O88420 CHEMBL2752 Sodium Channel Protein Type VIII Alpha Subunit, Rat 2
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 2
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 1
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 1
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 1
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 1
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 1
5HT2A_PIG P50129 CHEMBL2490 Serotonin 2a (5-HT2a) Receptor, Pig 1
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 1
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 1
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 1
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 1
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 1
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 1
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 1
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 1
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 1
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 1
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 1
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 1
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 1
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 1
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 1
AP2S1_RAT P62744 CHEMBL1697667 AP-2 Complex Subunit Sigma, Rat 1
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 1
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
DRD2_CHLAE P52702 CHEMBL5456 Dopamine D2 Receptor, Chlae 1
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 1
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 1
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 1
Q4U254_9ENTO Q4U254 CHEMBL2857 Human Rhinovirus A Protease, 9ento 1
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 1
Q72874_9HIV1 Q72874 CHEMBL243 Human Immunodeficiency Virus Type 1 Protease, 9hiv1 1
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 1

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