UCSF

Serotonin Transporter, Rat (3,586 Compounds)

Swissprot:
SC6A4_RAT
Stitch:
SC6A4_RAT
UniProt:
P31652
ChEMBL:
CHEMBL313
PDB:
Slc6a4

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 3,586 155 40 53
Binding ≤ 1μM 2,911 129 35 47
Functional ≤ 10μM 535 47 30 38

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 4,112 205 45 56
SC6A4_MACMU Q9MYX0 CHEMBL5453 Serotonin Transporter, Macmu 71 4 0 0
SC6A4_MOUSE Q60857 CHEMBL4642 Serotonin Transporter, Mouse 63 5 4 4
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SC6A1_RAT P23978 CHEMBL4054 GABA Transporter 1, Rat 105 11 7 3
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 2,890 133 48 52
SC6A5_RAT P58295 CHEMBL3195 Glycine Transporter 2, Rat 12 2 0 0
SC6A8_RAT P28570 CHEMBL3814 Creatine Transporter, Rat 2 0 0 0
SC6A9_RAT P28572 CHEMBL4556 Glycine Transporter 1, Rat 27 2 0 0

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
SC6A4-1-E Serotonin Transporter (cluster #1 Of 4), Eukaryotic 3,920 115 35 40
SC6A4-2-E Serotonin Transporter (cluster #2 Of 4), Eukaryotic 158 11 1 2
SC6A4-3-E Serotonin Transporter (cluster #3 Of 4), Eukaryotic 2,816 189 30 44
SC6A4-4-E Serotonin Transporter (cluster #4 Of 4), Eukaryotic 459 20 6 4
Uniprot Swissprot Chembl Description Number Shared
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 2109
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 1470
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 643
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 417
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 323
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 269
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 186
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 183
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 181
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 181
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 164
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 138
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 91
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 90
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 80
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 79
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 79
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 68
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 64
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 54
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 52
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 49
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 45
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 40
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 30
MC4R_HUMAN P32245 CHEMBL259 Melanocortin Receptor 4, Human 30
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 26
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 26
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 24
AOFA_RAT P21396 CHEMBL3358 Monoamine Oxidase A, Rat 23
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 22
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 22
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 22
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 21
ADRB3_RAT P26255 CHEMBL4031 Beta-3 Adrenergic Receptor, Rat 21
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 21
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 21
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 20
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 20
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 20
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 20
ADRB2_CANFA P54833 CHEMBL2289 Beta-2 Adrenergic Receptor, Canine 19
VMAT2_RAT Q01827 CHEMBL4828 Synaptic Vesicular Amine Transporter, Rat 19
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 18
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 18
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 18
SC6A3_MOUSE Q61327 CHEMBL2799 Dopamine Transporter, Mouse 18
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 17
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 17
SC6A2_MOUSE O55192 CHEMBL2370 Norepinephrine Transporter, Mouse 16
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 16
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 15
AOFB_RAT P19643 CHEMBL2993 Monoamine Oxidase B, Rat 15
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 14
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 14
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 14
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 13
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 13
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 11
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 10
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 9
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 8
VACHT_HUMAN Q16572 CHEMBL4767 Vesicular Acetylcholine Transporter, Human 8
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 7
SC6A4_MOUSE Q60857 CHEMBL4642 Serotonin Transporter, Mouse 7
Z50594 Z50594 CHEMBL375 Mus Musculus 7
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 6
SC6A3_BOVIN P27922 CHEMBL2986 Dopamine Transporter, Bovin 6
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 5
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 5
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 5
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 5
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 5
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 5
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 5
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 5
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 5
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 5
5HT6R_RAT P31388 CHEMBL3372 Serotonin 6 (5-HT6) Receptor, Rat 4
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 4
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 4
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 4
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 4
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 4
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 4
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 4
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 3
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 3
5HT3A_MOUSE P23979 CHEMBL4972 Serotonin 3a (5-HT3a) Receptor, Mouse 3
5HT3B_HUMAN O95264 CHEMBL3895 Serotonin 3b (5-HT3b) Receptor, Human 3
5HT3B_MOUSE Q9JHJ5 CHEMBL3781 Serotonin 3b (5-HT3b) Receptor, Mouse 3
5HT3C_HUMAN Q8WXA8 CHEMBL4795 Serotonin 3c (5-HT3c) Receptor, Human 3
5HT3D_HUMAN Q70Z44 CHEMBL4673 Serotonin 3d (5-HT3d) Receptor, Human 3
5HT3E_HUMAN A5X5Y0 CHEMBL3812 Serotonin 3e (5-HT3e) Receptor, Human 3
5HT4R_HUMAN Q13639 CHEMBL1875 Serotonin 4 (5-HT4) Receptor, Human 3
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 3
5HT5A_RAT P35364 CHEMBL4655 Serotonin 5a (5-HT5a) Receptor, Rat 3
5HT5B_RAT P35365 CHEMBL2619 Serotonin 5b (5-HT5b) Receptor, Rat 3
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 3
ACHA7_RAT Q05941 CHEMBL4980 Neuronal Acetylcholine Receptor Protein Alpha-7 Subunit, Rat 3
ACM5_RAT P08911 CHEMBL277 Muscarinic Acetylcholine Receptor M5, Rat 3
ADRB2_RAT P10608 CHEMBL3754 Beta-2 Adrenergic Receptor, Rat 3
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 3
HRH2_HUMAN P25021 CHEMBL1941 Histamine H2 Receptor, Human 3
Z104290 Z104290 CHEMBL1907596 Neuronal Acetylcholine Receptor; Alpha4/beta2 3
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 3
Z50466 Z50466 CHEMBL368 Trypanosoma Cruzi 3
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 2
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 2
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 2
ACH10_RAT Q9JLB5 CHEMBL3461 Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Rat 2
ACHA2_RAT P12389 CHEMBL2584 Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Rat 2
ACHA3_RAT P04757 CHEMBL3818 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Rat 2
ACHA4_RAT P09483 CHEMBL307 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Rat 2
ACHA5_RAT P20420 CHEMBL4960 Neuronal Acetylcholine Receptor Protein Alpha-5 Subunit, Rat 2
ACHA6_RAT P43143 CHEMBL4747 Neuronal Acetylcholine Receptor Protein Alpha-6 Subunit, Rat 2
ACHA9_RAT P43144 CHEMBL2585 Neuronal Acetylcholine Receptor Protein Alpha-9 Subunit, Rat 2
ACHA_RAT P25108 CHEMBL3599 Acetylcholine Receptor Protein Alpha Chain, Rat 2
ACHB2_RAT P12390 CHEMBL3001 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Rat 2
ACHB3_RAT P12391 CHEMBL4568 Neuronal Acetylcholine Receptor Protein Beta-3 Subunit, Rat 2
ACHB4_RAT P12392 CHEMBL2658 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat 2
ACHB_RAT P25109 CHEMBL2666 Acetylcholine Receptor Protein Beta Chain, Rat 2
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 2
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 2
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 2
HRH1_CAVPO P31389 CHEMBL3943 Histamine H1 Receptor, Guinea Pig 2
HRH2_RAT P25102 CHEMBL4654 Histamine H2 Receptor, Rat 2
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 2
HRH4_RAT Q91ZY1 CHEMBL4468 Histamine H4 Receptor, Rat 2
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 2
SC6A3_MACFA Q9GJT6 CHEMBL5032 Dopamine Transporter, Macfa 2
SGMR1_MOUSE O55242 CHEMBL3465 Sigma Opioid Receptor, Mouse 2
Z100251 Z100251 CHEMBL612442 Monoclonal Antibody (mAb) 2E2 2
5HT1A_MOUSE Q64264 CHEMBL3737 Serotonin 1a (5-HT1a) Receptor, Mouse 1
5HT1D_PIG P79400 CHEMBL4105 Serotonin 1d (5-HT1d) Receptor, Pig 1
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 1
5HT4R_CAVPO O70528 CHEMBL5017 Serotonin 4 (5-HT4) Receptor, Guinea Pig 1
5HT5A_MOUSE P30966 CHEMBL3597 Serotonin 5a (5-HT5a) Receptor, Mouse 1
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 1
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 1
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 1
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 1
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 1
ADA2B_BOVIN O77700 CHEMBL3523 Alpha-2b Adrenergic Receptor, Bovin 1
ALDR_RAT P07943 CHEMBL2622 Aldose Reductase, Rat 1
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 1
GPR44_HUMAN Q9Y5Y4 CHEMBL5071 G Protein-coupled Receptor 44, Human 1
HRH2_CAVPO P47747 CHEMBL2882 Histamine H2 Receptor, Guinea Pig 1
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 1
NORA_STAAU P0A0J7 CHEMBL5114 Quinolone Resistance Protein NorA, Staau 1
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 1
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 1
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 1
OPRK_CAVPO P41144 CHEMBL3952 Kappa Opioid Receptor, Guinea Pig 1
OPRK_MOUSE P33534 CHEMBL4329 Kappa Opioid Receptor, Mouse 1
OPRX_RAT P35370 CHEMBL4503 Nociceptin Receptor, Rat 1
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 1
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 1
PRIO_HUMAN P04156 CHEMBL4869 Prion Protein, Human 1
VACHT_RAT Q62666 CHEMBL2125 Vesicular Acetylcholine Transporter, Rat 1
VMAT1_RAT Q01818 CHEMBL2702 Vesicular Amine Transporter 1, Rat 1
VMAT2_HUMAN Q05940 CHEMBL1893 Synaptic Vesicular Amine Transporter, Human 1
Z50185 Z50185 CHEMBL352 Staphylococcus Aureus 1
Z50590 Z50590 CHEMBL613488 Sus Scrofa 1
Z50796 Z50796 CHEMBL614874 Monkey 1
Z81138 Z81138 CHEMBL613872 ScN2a (Scrapie-infected Neuroblastoma Cells) 1

Most Common Rings