UCSF

Serotonin Transporter, Mouse (63 Compounds)

Swissprot:
SC6A4_MOUSE
Stitch:
SC6A4_MOUSE
UniProt:
Q60857
ChEMBL:
CHEMBL4642
PDB:
Slc6a4

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 63 5 4 4
Binding ≤ 1μM 54 4 3 3

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 4,112 205 45 56
SC6A4_MACMU Q9MYX0 CHEMBL5453 Serotonin Transporter, Macmu 71 4 0 0
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 3,586 155 40 53
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SC6A1_MOUSE P31648 CHEMBL5445 GABA Transporter 1, Mouse 23 5 2 1
SC6A2_MOUSE O55192 CHEMBL2370 Norepinephrine Transporter, Mouse 52 9 5 6
SC6A3_MOUSE Q61327 CHEMBL2799 Dopamine Transporter, Mouse 55 10 6 7
SC6A9_MOUSE P28571 CHEMBL1075303 Sodium- And Chloride-dependent Glycine Transporter 1, Mouse 6 0 0 0

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
SC6A4-1-E Serotonin Transporter (cluster #1 Of 4), Eukaryotic 3,920 115 35 40
SC6A4-2-E Serotonin Transporter (cluster #2 Of 4), Eukaryotic 158 11 1 2
SC6A4-3-E Serotonin Transporter (cluster #3 Of 4), Eukaryotic 2,816 189 30 44
SC6A4-4-E Serotonin Transporter (cluster #4 Of 4), Eukaryotic 459 20 6 4
Uniprot Swissprot Chembl Description Number Shared
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 63
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 54
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 53
SC6A3_BOVIN P27922 CHEMBL2986 Dopamine Transporter, Bovin 43
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 43
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 14
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 13
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 9
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 8
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 8
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 8
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 7
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 7
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 7
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 7
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 7
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 7
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 6
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 6
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 6
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 4
CCR3_HUMAN P51677 CHEMBL3473 C-C Chemokine Receptor Type 3, Human 4
CCR3_MOUSE P51678 CHEMBL3406 C-C Chemokine Receptor Type 3, Mouse 4
CCR3_RAT O54814 CHEMBL3928 C-C Chemokine Receptor Type 3, Rat 4
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 4
OPRX_RAT P35370 CHEMBL4503 Nociceptin Receptor, Rat 4
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 3
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 3
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 3
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 3
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 3
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 2
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 2
CCR1_HUMAN P32246 CHEMBL2413 C-C Chemokine Receptor Type 1, Human 2
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 2
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 2
CXCR1_HUMAN P25024 CHEMBL4029 Interleukin-8 Receptor A, Human 2
CXCR2_HUMAN P25025 CHEMBL2434 Interleukin-8 Receptor B, Human 2
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 2
SC6A2_MOUSE O55192 CHEMBL2370 Norepinephrine Transporter, Mouse 2
SC6A3_MACFA Q9GJT6 CHEMBL5032 Dopamine Transporter, Macfa 2
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 2
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 2
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 2
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 2
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 2
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 2
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 1
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 1
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 1
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 1
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 1
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 1
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 1
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 1
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 1
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 1
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 1
5HT5A_RAT P35364 CHEMBL4655 Serotonin 5a (5-HT5a) Receptor, Rat 1
5HT5B_RAT P35365 CHEMBL2619 Serotonin 5b (5-HT5b) Receptor, Rat 1
5HT6R_RAT P31388 CHEMBL3372 Serotonin 6 (5-HT6) Receptor, Rat 1
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 1
ACM5_RAT P08911 CHEMBL277 Muscarinic Acetylcholine Receptor M5, Rat 1
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 1
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 1
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 1
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 1
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 1
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 1
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 1
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 1
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 1
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 1
ADCY5_HUMAN O95622 CHEMBL3189 Adenylate Cyclase Type V, Human 1
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 1
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 1
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 1
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 1
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 1
ADRB2_RAT P10608 CHEMBL3754 Beta-2 Adrenergic Receptor, Rat 1
ADRB3_RAT P26255 CHEMBL4031 Beta-3 Adrenergic Receptor, Rat 1
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 1
DRD1_MOUSE Q61616 CHEMBL3071 Dopamine D1 Receptor, Mouse 1
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 1
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 1
HRH2_RAT P25102 CHEMBL4654 Histamine H2 Receptor, Rat 1
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 1
HRH4_RAT Q91ZY1 CHEMBL4468 Histamine H4 Receptor, Rat 1
PRIO_HUMAN P04156 CHEMBL4869 Prion Protein, Human 1
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 1
SC6A3_MOUSE Q61327 CHEMBL2799 Dopamine Transporter, Mouse 1
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 1
Z100251 Z100251 CHEMBL612442 Monoclonal Antibody (mAb) 2E2 1
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 1
Z50796 Z50796 CHEMBL614874 Monkey 1