UCSF

Dopamine D2 Receptor, Human (3,672 Compounds)

Swissprot:
DRD2_HUMAN
Stitch:
DRD2_HUMAN
UniProt:
P14416
ChEMBL:
CHEMBL217
Reactome:
REACT_16968
REACT_19231
PDB:
1I15 (DOCK)
2HLB (DOCK)
DRD2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 3,672 241 71 74
Binding ≤ 1μM 2,888 182 59 66
Functional ≤ 10μM 330 35 17 17

Reactome Network (2)

Reactome ID Description Species
REACT_16968 Dopamine receptors Homo sapiens
REACT_19231 G alpha (i) signalling events Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 502
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1939
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1283
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 193

G alpha (i) signalling events

Uniprot Swissprot Chembl Description Number Shared
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 607
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 60
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 66
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 19
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 13
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 26
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 3
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 14
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 24
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 33
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 82
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 34
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 53
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 3
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 3
ADCY5_HUMAN O95622 CHEMBL3189 Adenylate Cyclase Type V, Human 2
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 3
CCR1_HUMAN P32246 CHEMBL2413 C-C Chemokine Receptor Type 1, Human 2
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 2
CCR3_HUMAN P51677 CHEMBL3473 C-C Chemokine Receptor Type 3, Human 18
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 2
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 3
CXCR1_HUMAN P25024 CHEMBL4029 Interleukin-8 Receptor A, Human 2
CXCR2_HUMAN P25025 CHEMBL2434 Interleukin-8 Receptor B, Human 2
CXCR3_HUMAN P49682 CHEMBL4441 C-X-C Chemokine Receptor Type 3, Human 1
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1939
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1283
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 12
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 3
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 15
MTR1A_HUMAN P48039 CHEMBL1945 Melatonin Receptor 1A, Human 3
MTR1B_HUMAN P49286 CHEMBL1946 Melatonin Receptor 1B, Human 1
NPY1R_HUMAN P25929 CHEMBL4777 Neuropeptide Y Receptor Type 1, Human 6
NPY5R_HUMAN Q15761 CHEMBL4561 Neuropeptide Y Receptor Type 5, Human 2
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 11
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 15
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 17
OPRX_HUMAN P41146 CHEMBL2014 Nociceptin Receptor, Human 5
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 5
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 425 51 18 25
DRD2_CANFA Q9GJU1 CHEMBL2703 Dopamine D2 Receptor, Canine 2 2 2 2
DRD2_CHLAE P52702 CHEMBL5456 Dopamine D2 Receptor, Chlae 14 2 2 2
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 137 8 4 4
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 4,526 318 108 115
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 653 67 30 30
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 2,290 174 48 59
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1,846 158 44 42
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 215 21 16 14

Clustered By Gene (0)

Clustered By Organism (23)

Code Description Substances Purchasable Natural In Man
DRD2-1-E Dopamine D2 Receptor (cluster #1 Of 24), Eukaryotic 33 2 1 1
DRD2-10-E Dopamine D2 Receptor (cluster #10 Of 24), Eukaryotic 25 2 0 0
DRD2-11-E Dopamine D2 Receptor (cluster #11 Of 24), Eukaryotic 86 16 2 4
DRD2-12-E Dopamine D2 Receptor (cluster #12 Of 24), Eukaryotic 3 0 0 0
DRD2-13-E Dopamine D2 Receptor (cluster #13 Of 24), Eukaryotic 1 0 0 0
DRD2-14-E Dopamine D2 Receptor (cluster #14 Of 24), Eukaryotic 70 19 12 15
DRD2-15-E Dopamine D2 Receptor (cluster #15 Of 24), Eukaryotic 339 16 9 10
DRD2-16-E Dopamine D2 Receptor (cluster #16 Of 24), Eukaryotic 114 17 6 3
DRD2-17-E Dopamine D2 Receptor (cluster #17 Of 24), Eukaryotic 1,119 52 13 21
DRD2-18-E Dopamine D2 Receptor (cluster #18 Of 24), Eukaryotic 103 3 1 3
DRD2-19-E Dopamine D2 Receptor (cluster #19 Of 24), Eukaryotic 62 0 0 0
DRD2-2-E Dopamine D2 Receptor (cluster #2 Of 24), Eukaryotic 2,742 230 57 42
DRD2-20-E Dopamine D2 Receptor (cluster #20 Of 24), Eukaryotic 171 6 2 3
DRD2-21-E Dopamine D2 Receptor (cluster #21 Of 24), Eukaryotic 41 0 0 0
DRD2-22-E Dopamine D2 Receptor (cluster #22 Of 24), Eukaryotic 30 20 4 4
DRD2-23-E Dopamine D2 Receptor (cluster #23 Of 24), Eukaryotic 381 15 7 9
DRD2-24-E Dopamine D2 Receptor (cluster #24 Of 24), Eukaryotic 1 1 1 1
DRD2-3-E Dopamine D2 Receptor (cluster #3 Of 24), Eukaryotic 265 14 7 7
DRD2-4-E Dopamine D2 Receptor (cluster #4 Of 24), Eukaryotic 1,893 45 14 24
DRD2-5-E Dopamine D2 Receptor (cluster #5 Of 24), Eukaryotic 28 1 0 0
DRD2-6-E Dopamine D2 Receptor (cluster #6 Of 24), Eukaryotic 454 25 4 5
DRD2-7-E Dopamine D2 Receptor (cluster #7 Of 24), Eukaryotic 81 8 4 4
DRD2-8-E Dopamine D2 Receptor (cluster #8 Of 24), Eukaryotic 184 8 1 2
DRD2-9-E Dopamine D2 Receptor (cluster #9 Of 24), Eukaryotic 327 17 2 2
Uniprot Swissprot Chembl Description Number Shared
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1908
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1263
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 636
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 590
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 499
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 409
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 380
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 333
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 325
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 278
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 209
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 207
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 193
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 193
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 173
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 164
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 163
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 154
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 152
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 140
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 129
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 122
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 121
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 118
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 98
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 95
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 90
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 87
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 81
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 81
5HT2A_PIG P50129 CHEMBL2490 Serotonin 2a (5-HT2a) Receptor, Pig 76
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 69
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 66
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 64
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 63
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 63
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 59
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 58
ADA1B_MESAU P18841 CHEMBL3122 Alpha-1b Adrenergic Receptor, Mesau 54
SGMR1_CAVPO Q60492 CHEMBL4153 Sigma-1 Receptor, Guinea Pig 54
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 52
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 52
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 49
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 47
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 45
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 44
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 37
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 34
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 33
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 33
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 33
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 29
5HT1A_MOUSE Q64264 CHEMBL3737 Serotonin 1a (5-HT1a) Receptor, Mouse 28
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 27
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 26
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 25
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 25
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 25
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 24
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 24
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 23
EPYC_HUMAN Q99645 CHEMBL2080 Small Chondroitin/dermatan Sulfate Proteoglycan, Human 23
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 23
TA2R_HUMAN P21731 CHEMBL2069 Thromboxane A2 Receptor, Human 23
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 22
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 22
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 22
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 22
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 22
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 22
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 18
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 18
CCR3_HUMAN P51677 CHEMBL3473 C-C Chemokine Receptor Type 3, Human 18
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 17
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 17
Z100491 Z100491 CHEMBL613288 Sigma 2 Receptor 16
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 15
MCHR1_HUMAN Q99705 CHEMBL344 Melanin-concentrating Hormone Receptor 1, Human 15
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 15
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 15
HRH2_HUMAN P25021 CHEMBL1941 Histamine H2 Receptor, Human 14
SC6A4_MOUSE Q60857 CHEMBL4642 Serotonin Transporter, Mouse 14
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 13
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 13
DRD1_MOUSE Q61616 CHEMBL3071 Dopamine D1 Receptor, Mouse 12
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 12
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 12
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 12
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 12
5HT4R_HUMAN Q13639 CHEMBL1875 Serotonin 4 (5-HT4) Receptor, Human 11
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 11
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 11
SC6A3_RAT P23977 CHEMBL338 Dopamine Transporter, Rat 11
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 11
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 10
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 10
AP2S1_RAT P62744 CHEMBL1697667 AP-2 Complex Subunit Sigma, Rat 10
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 10
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 9
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 9
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 9
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 9
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 9
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 9
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 8
5HT5A_RAT P35364 CHEMBL4655 Serotonin 5a (5-HT5a) Receptor, Rat 8
CAC1F_HUMAN O60840 CHEMBL5593 Voltage-gated L-type Calcium Channel Alpha-1F Subunit, Human 8
CAC1S_HUMAN Q13698 CHEMBL3805 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Human 8
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 8
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 7
CAC1C_HUMAN Q13936 CHEMBL1940 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Human 7
CAC1D_HUMAN Q01668 CHEMBL4138 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Human 7
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 7
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 6
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 6
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 6
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 6
NPY1R_HUMAN P25929 CHEMBL4777 Neuropeptide Y Receptor Type 1, Human 6
OPRX_RAT P35370 CHEMBL4503 Nociceptin Receptor, Rat 6
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 6
5HT5B_RAT P35365 CHEMBL2619 Serotonin 5b (5-HT5b) Receptor, Rat 5
5HT6R_RAT P31388 CHEMBL3372 Serotonin 6 (5-HT6) Receptor, Rat 5
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 5
ADRB3_RAT P26255 CHEMBL4031 Beta-3 Adrenergic Receptor, Rat 5
CCR3_MOUSE P51678 CHEMBL3406 C-C Chemokine Receptor Type 3, Mouse 5
D4A3N4_RAT D4A3N4 CHEMBL2679 Brain Adenylate Cyclase 1, Rat 5
HRH1_CAVPO P31389 CHEMBL3943 Histamine H1 Receptor, Guinea Pig 5
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 5
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 5
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 5
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 5
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 5
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 5
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 5
OPRX_HUMAN P41146 CHEMBL2014 Nociceptin Receptor, Human 5
PDR5_YEAST P33302 CHEMBL1697658 Pleiotropic ABC Efflux Transporter Of Multiple Drugs, Yeast 5
PE2R3_HUMAN P43115 CHEMBL3710 Prostanoid EP3 Receptor, Human 5
PE2R4_HUMAN P35408 CHEMBL1836 Prostanoid EP4 Receptor, Human 5
PI2R_HUMAN P43119 CHEMBL1995 Prostanoid IP Receptor, Human 5
SC6A3_BOVIN P27922 CHEMBL2986 Dopamine Transporter, Bovin 5
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 4
CCR3_RAT O54814 CHEMBL3928 C-C Chemokine Receptor Type 3, Rat 4
CRFR1_RAT P35353 CHEMBL4649 Corticotropin Releasing Factor Receptor 1, Rat 4
CRFR2_MOUSE Q60748 CHEMBL2253 Corticotropin Releasing Factor Receptor 2, Mouse 4
GRM2_RAT P31421 CHEMBL2851 Metabotropic Glutamate Receptor 2, Rat 4
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 4
NK2R_HUMAN P21452 CHEMBL2327 Neurokinin 2 Receptor, Human 4
PE2R2_HUMAN P43116 CHEMBL1881 Prostanoid EP2 Receptor, Human 4
SCN2A_RAT P04775 CHEMBL3399 Sodium Channel Protein Type II Alpha Subunit, Rat 4
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 4
Z50512 Z50512 CHEMBL369 Cavia Porcellus 4
5HT3A_MOUSE P23979 CHEMBL4972 Serotonin 3a (5-HT3a) Receptor, Mouse 3
5HT3B_HUMAN O95264 CHEMBL3895 Serotonin 3b (5-HT3b) Receptor, Human 3
5HT3E_HUMAN A5X5Y0 CHEMBL3812 Serotonin 3e (5-HT3e) Receptor, Human 3
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 3
AA2BR_RAT P29276 CHEMBL2592 Adenosine A2b Receptor, Rat 3
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 3
ACM5_RAT P08911 CHEMBL277 Muscarinic Acetylcholine Receptor M5, Rat 3
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 3
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 3
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 3
ADRB2_RAT P10608 CHEMBL3754 Beta-2 Adrenergic Receptor, Rat 3
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 3
HRH2_RAT P25102 CHEMBL4654 Histamine H2 Receptor, Rat 3
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 3
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 3
HRH4_RAT Q91ZY1 CHEMBL4468 Histamine H4 Receptor, Rat 3
MTR1A_HUMAN P48039 CHEMBL1945 Melatonin Receptor 1A, Human 3
NK1R_HUMAN P25103 CHEMBL249 Neurokinin 1 Receptor, Human 3
SCN1A_RAT P04774 CHEMBL4906 Sodium Channel Protein Type I Alpha Subunit, Rat 3
SCN3A_RAT P08104 CHEMBL4966 Sodium Channel Protein Type III Alpha Subunit, Rat 3
SCN8A_RAT O88420 CHEMBL2752 Sodium Channel Protein Type VIII Alpha Subunit, Rat 3
SGMR1_MOUSE O55242 CHEMBL3465 Sigma Opioid Receptor, Mouse 3
VACHT_HUMAN Q16572 CHEMBL4767 Vesicular Acetylcholine Transporter, Human 3
Z50594 Z50594 CHEMBL375 Mus Musculus 3
5HT3A_CAVPO O70212 CHEMBL3666 Serotonin 3a (5-HT3a) Receptor, Guinea Pig 2
5HT3C_HUMAN Q8WXA8 CHEMBL4795 Serotonin 3c (5-HT3c) Receptor, Human 2
5HT3D_HUMAN Q70Z44 CHEMBL4673 Serotonin 3d (5-HT3d) Receptor, Human 2
5HT4R_CAVPO O70528 CHEMBL5017 Serotonin 4 (5-HT4) Receptor, Guinea Pig 2
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 2
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 2
ADCY5_HUMAN O95622 CHEMBL3189 Adenylate Cyclase Type V, Human 2
ADRB2_CANFA P54833 CHEMBL2289 Beta-2 Adrenergic Receptor, Canine 2
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 2
B5SU02_9CNID B5SU02 CHEMBL1075028 Alpha Carbonic Anhydrase, 9cnid 2
C0IX24_9CNID C0IX24 CHEMBL1649055 Carbonic Anhydrase, 9cnid 2
CAC1C_RAT P22002 CHEMBL3762 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat 2
CAH12_HUMAN O43570 CHEMBL3242 Carbonic Anhydrase XII, Human 2
CAH15_MOUSE Q99N23 CHEMBL5973 Carbonic Anhydrase 15, Mouse 2
CAH1_HUMAN P00915 CHEMBL261 Carbonic Anhydrase I, Human 2
CAH2_HUMAN P00918 CHEMBL205 Carbonic Anhydrase II, Human 2
CAH4_BOVIN Q95323 CHEMBL281 Carbonic Anhydrase IV, Bovin 2
CAH5A_HUMAN P35218 CHEMBL4789 Carbonic Anhydrase VA, Human 2
CAH5B_HUMAN Q9Y2D0 CHEMBL3969 Carbonic Anhydrase VB, Human 2
CAH6_HUMAN P23280 CHEMBL3025 Carbonic Anhydrase VI, Human 2
CAH9_HUMAN Q16790 CHEMBL3594 Carbonic Anhydrase IX, Human 2
CAN_YEAST P53615 CHEMBL5931 Carbonic Anhydrase, Yeast 2
CCR1_HUMAN P32246 CHEMBL2413 C-C Chemokine Receptor Type 1, Human 2
CCR2_HUMAN P41597 CHEMBL4015 C-C Chemokine Receptor Type 2, Human 2
CCR5_HUMAN P51681 CHEMBL274 C-C Chemokine Receptor Type 5, Human 2
CXCR1_HUMAN P25024 CHEMBL4029 Interleukin-8 Receptor A, Human 2
CXCR2_HUMAN P25025 CHEMBL2434 Interleukin-8 Receptor B, Human 2
CYNT_HELPY O24855 CHEMBL4211 Carbonic Anhydrase 1, Helpy 2
CYNT_MYCTU O53573 CHEMBL6068 Carbonic Anhydrase, Myctu 2
DRD2_CANFA Q9GJU1 CHEMBL2703 Dopamine D2 Receptor, Canine 2
DRD2_CHLAE P52702 CHEMBL5456 Dopamine D2 Receptor, Chlae 2
EDNRA_HUMAN P25101 CHEMBL252 Endothelin Receptor ET-A, Human 2
GASR_HUMAN P32239 CHEMBL298 Cholecystokinin B Receptor, Human 2
GCR_HUMAN P04150 CHEMBL2034 Glucocorticoid Receptor, Human 2
KD4DL_HUMAN B2RXH2 CHEMBL1293226 Lysine-specific Demethylase 4D-like, Human 2
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 2
MC4R_HUMAN P32245 CHEMBL259 Melanocortin Receptor 4, Human 2
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 2
MT3_HUMAN P25713 CHEMBL1250357 Metallothionein-3, Human 2
NISCH_HUMAN Q9Y2I1 CHEMBL3923 Nischarin, Human 2
NPY5R_HUMAN Q15761 CHEMBL4561 Neuropeptide Y Receptor Type 5, Human 2
NPY5R_RAT Q63634 CHEMBL2548 Neuropeptide Y Receptor Type 5, Rat 2
NTR1_HUMAN P30989 CHEMBL4123 Neurotensin Receptor 1, Human 2
PRIO_HUMAN P04156 CHEMBL4869 Prion Protein, Human 2
Q5AJ71_CANAL Q5AJ71 CHEMBL5337 Carbonic Anhydrase, Canal 2
SC5A7_HUMAN Q9GZV3 CHEMBL4507 High-affinity Choline Transporter, Human 2
SC6A2_MOUSE O55192 CHEMBL2370 Norepinephrine Transporter, Mouse 2
Y1284_MYCTU P64797 CHEMBL5631 Uncharacterized Protein Rv1284/MT1322, Myctu 2
Z104283 Z104283 CHEMBL1907589 Neuronal Acetylcholine Receptor; Alpha4/beta2 2
5HT1D_PIG P79400 CHEMBL4105 Serotonin 1d (5-HT1d) Receptor, Pig 1
5HT3B_MOUSE Q9JHJ5 CHEMBL3781 Serotonin 3b (5-HT3b) Receptor, Mouse 1
5HT4R_MOUSE P97288 CHEMBL2183 Serotonin 4 (5-HT4) Receptor, Mouse 1
5HT7R_MOUSE P32304 CHEMBL4764 Serotonin 7 (5-HT7) Receptor, Mouse 1
ACES_TORCA P04058 CHEMBL4780 Acetylcholinesterase, Torca 1
ACM4_RAT P08485 CHEMBL317 Muscarinic Acetylcholine Receptor M4, Rat 1
ADA1A_RABIT O02824 CHEMBL3637 Alpha-1a Adrenergic Receptor, Rabit 1
ADA1D_RABIT O02666 CHEMBL4407 Alpha-1d Adrenergic Receptor, Rabit 1
ADA2B_BOVIN O77700 CHEMBL3523 Alpha-2b Adrenergic Receptor, Bovin 1
ANDR_RAT P15207 CHEMBL3072 Androgen Receptor, Rat 1
ARP19_RAT Q712U5 CHEMBL2170 Cyclic AMP Phosphoprotein, Rat 1
CAC1D_RAT P27732 CHEMBL4132 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Rat 1
CAC1G_HUMAN O43497 CHEMBL4641 Voltage-gated T-type Calcium Channel Alpha-1G Subunit, Human 1
CAC1S_RAT Q02485 CHEMBL4108 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Rat 1
CALM_HUMAN P62158 CHEMBL6093 Calmodulin, Human 1
CHLE_HUMAN P06276 CHEMBL1914 Butyrylcholinesterase, Human 1
CXCR3_HUMAN P49682 CHEMBL4441 C-X-C Chemokine Receptor Type 3, Human 1
CXCR3_MOUSE O88410 CHEMBL5200 C-X-C Chemokine Receptor Type 3, Mouse 1
DRD4_MOUSE P51436 CHEMBL2574 Dopamine D4 Receptor, Mouse 1
EBP_HUMAN Q15125 CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human 1
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 1
HRH2_CAVPO P47747 CHEMBL2882 Histamine H2 Receptor, Guinea Pig 1
KCNQ1_HUMAN P51787 CHEMBL1866 Voltage-gated Potassium Channel Subunit Kv7.1, Human 1
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 1
MCHR1_RAT P97639 CHEMBL1075228 Melanin-concentrating Hormone Receptor 1, Rat 1
MTR1B_HUMAN P49286 CHEMBL1946 Melatonin Receptor 1B, Human 1
NOS1_HUMAN P29475 CHEMBL3568 Nitric-oxide Synthase, Brain, Human 1
NOS1_RAT P29476 CHEMBL3048 Nitric-oxide Synthase, Brain, Rat 1
NOS3_HUMAN P29474 CHEMBL4803 Nitric-oxide Synthase, Endothelial, Human 1
PD2R_HUMAN Q13258 CHEMBL4427 Prostanoid DP Receptor, Human 1
PF2R_HUMAN P43088 CHEMBL1987 Prostanoid FP Receptor, Human 1
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 1
Q4U254_9ENTO Q4U254 CHEMBL2857 Human Rhinovirus A Protease, 9ento 1
Q72874_9HIV1 Q72874 CHEMBL243 Human Immunodeficiency Virus Type 1 Protease, 9hiv1 1
SC6A3_MACFA Q9GJT6 CHEMBL5032 Dopamine Transporter, Macfa 1
SC6A3_MOUSE Q61327 CHEMBL2799 Dopamine Transporter, Mouse 1
SMO_HUMAN Q99835 CHEMBL5971 Smoothened Homolog, Human 1
TRPV1_RAT O35433 CHEMBL5102 Vanilloid Receptor, Rat 1
TYTR_TRYCR P28593 CHEMBL5131 Trypanothione Reductase, Trycr 1
UR2R_HUMAN Q9UKP6 CHEMBL3764 Urotensin II Receptor, Human 1
V1AR_HUMAN P37288 CHEMBL1889 Vasopressin V1a Receptor, Human 1
V1BR_RAT P48974 CHEMBL2659 Vasopressin V1b Receptor, Rat 1
Z100251 Z100251 CHEMBL612442 Monoclonal Antibody (mAb) 2E2 1
Z50587 Z50587 CHEMBL372 Homo Sapiens 1
Z50588 Z50588 CHEMBL373 Canis Familiaris 1
Z50796 Z50796 CHEMBL614874 Monkey 1
Z80088 Z80088 CHEMBL613853 CHO (Ovarian Cells) 1
Z80091 Z80091 CHEMBL614557 CHO-hD3 1
Z80334 Z80334 CHEMBL613828 NG108-15 (Neuroblastoma-glioma Hybrid Cells) 1

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