UCSF
Image of Thiazole

Identity 99% 90% 80% 70% Substructure

Thiazole

PubMed — Wikipedia — Google

Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
1 1 5 3 1 0 1

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 108 239,524 547 22,785 9 2012-03-06

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 47 Annotations Catalogs SMILES SDF Mol2 Flexibase
MK14_HUMAN Q16539 CHEMBL260 MAP Kinase P38 Alpha, Human 47 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 45 Annotations Catalogs SMILES SDF Mol2 Flexibase
DCMC_HUMAN O95822 CHEMBL4698 Malonyl-CoA Decarboxylase, Human 43 Annotations Catalogs SMILES SDF Mol2 Flexibase
DCMC_HUMAN O95822 CHEMBL4698 Malonyl-CoA Decarboxylase, Human 43 Annotations Catalogs SMILES SDF Mol2 Flexibase
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 34 Annotations Catalogs SMILES SDF Mol2 Flexibase
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 33 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 29 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC5A2_HUMAN P31639 CHEMBL3884 Sodium/glucose Cotransporter 2, Human 27 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80548 Z80548 CHEMBL614245 THP-1 (Acute Monocytic Leukemia Cells) 26 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 25 Annotations Catalogs SMILES SDF Mol2 Flexibase
SC5A2_HUMAN P31639 CHEMBL3884 Sodium/glucose Cotransporter 2, Human 24 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 22 Annotations Catalogs SMILES SDF Mol2 Flexibase
NPY5R_HUMAN Q15761 CHEMBL4561 Neuropeptide Y Receptor Type 5, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2BR_HUMAN P29275 CHEMBL255 Adenosine A2b Receptor, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 17 Annotations Catalogs SMILES SDF Mol2 Flexibase
AK1A1_HUMAN P14550 CHEMBL2246 Aldehyde Reductase, Human 16 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCR4_HUMAN P51679 CHEMBL2414 C-C Chemokine Receptor Type 4, Human 14 Annotations Catalogs SMILES SDF Mol2 Flexibase
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 14 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z100750 Z100750 CHEMBL612548 Osteoclasts 14 Annotations Catalogs SMILES SDF Mol2 Flexibase
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCR4_HUMAN P51679 CHEMBL2414 C-C Chemokine Receptor Type 4, Human 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_RAT P31424 CHEMBL2564 Metabotropic Glutamate Receptor 5, Rat 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_RAT P31424 CHEMBL2564 Metabotropic Glutamate Receptor 5, Rat 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z100081 Z100081 CHEMBL613107 PBMC (Peripheral Blood Mononuclear Cells) 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2BR_HUMAN P29275 CHEMBL255 Adenosine A2b Receptor, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2BR_HUMAN P29275 CHEMBL255 Adenosine A2b Receptor, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
AMPM_ECOLI P0AE18 CHEMBL3423 Methionine Aminopeptidase, Ecoli 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
PTAFR_HUMAN P25105 CHEMBL250 Platelet Activating Factor Receptor, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
DCMC_MOUSE Q99J39 CHEMBL1255162 Malonyl-CoA Decarboxylase, Mitochondrial, Mouse 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC1_HUMAN Q13547 CHEMBL325 Histone Deacetylase 1, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC1_HUMAN Q13547 CHEMBL325 Histone Deacetylase 1, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80240 Z80240 CHEMBL614129 MDA-MB-361 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50587 Z50587 CHEMBL372 Homo Sapiens 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81331 Z81331 CHEMBL612262 SW-620 (Colon Adenocarcinoma Cells) 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACOD_HUMAN O00767 CHEMBL5555 Acyl-CoA Desaturase, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
DCMC_MOUSE Q99J39 CHEMBL1255162 Malonyl-CoA Decarboxylase, Mitochondrial, Mouse 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
INCE_HUMAN Q9NQS7 CHEMBL5177 Inner Centromere Protein, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
INCE_HUMAN Q9NQS7 CHEMBL5177 Inner Centromere Protein, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
LT4R1_HUMAN Q15722 CHEMBL3911 Leukotriene B4 Receptor 1, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
LUCI_LUCLA Q01158 CHEMBL3701 Luciferase, Lucla 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8SPQ9_CANFA Q8SPQ9 CHEMBL4033 Cyclooxygenase-2, Canine 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8SPQ9_CANFA Q8SPQ9 CHEMBL4033 Cyclooxygenase-2, Canine 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50417 Z50417 CHEMBL612848 Leishmania Infantum 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACOD_HUMAN O00767 CHEMBL5555 Acyl-CoA Desaturase, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADRB2_HUMAN P07550 CHEMBL210 Beta-2 Adrenergic Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
AMPM_ECOLI P0AE18 CHEMBL3423 Methionine Aminopeptidase, Ecoli 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
F16P1_HUMAN P09467 CHEMBL3975 Fructose-1,6-bisphosphatase, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
F16P1_HUMAN P09467 CHEMBL3975 Fructose-1,6-bisphosphatase, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
PTAFR_HUMAN P25105 CHEMBL250 Platelet Activating Factor Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
PTAFR_HUMAN P25105 CHEMBL250 Platelet Activating Factor Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
TRY2_BOVIN Q29463 CHEMBL4472 Trypsin II, Bovin 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACOD1_RAT P07308 CHEMBL5424 Acyl-CoA Desaturase 1, Rat 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACOD1_RAT P07308 CHEMBL5424 Acyl-CoA Desaturase 1, Rat 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ANDR_RAT P15207 CHEMBL3072 Androgen Receptor, Rat 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ANDR_RAT P15207 CHEMBL3072 Androgen Receptor, Rat 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
CATK_HUMAN P43235 CHEMBL268 Cathepsin K, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
CATK_HUMAN P43235 CHEMBL268 Cathepsin K, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
HDAC4_HUMAN P56524 CHEMBL3524 Histone Deacetylase 4, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
LEF_BACAN P15917 CHEMBL4372 Anthrax Lethal Factor, Bacan 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
LT4R1_HUMAN Q15722 CHEMBL3911 Leukotriene B4 Receptor 1, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
LT4R1_HUMAN Q15722 CHEMBL3911 Leukotriene B4 Receptor 1, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase