ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (606)
Reactome (1)
Related By:
Pathway (1)
Organism (3)
Gene (0)
Org. Clust. (7)
ChEMBL (103)
Rings (34)

Monoamine Oxidase B, Human (606 Compounds)

Swissprot:: AOFB_HUMAN
Stitch:: AOFB_HUMAN
UniProt:: P27338
ChEMBL:: CHEMBL2039
Reactome:: REACT_416
PDB:: 1GOS (DOCK); 1H8R (DOCK); 1OJ9 (DOCK); 1OJA (DOCK); 1OJC (DOCK); 1OJD (DOCK); 1S2Q (DOCK); 1S2Y (DOCK); 1S3B (DOCK); 1S3E (DOCK); 2BK3 (DOCK); 2BK4 (DOCK); 2BK5 (DOCK); 2BYB (DOCK); 2C64 (DOCK); 2C65 (DOCK); 2C66 (DOCK); 2C67 (DOCK); 2C70 (DOCK); 2C72 (DOCK); 2C73 (DOCK); 2C75 (DOCK); 2C76 (DOCK); 2V5Z (DOCK); 2V60 (DOCK); 2V61 (DOCK); 2VRL (DOCK); 2VRM (DOCK); 2VZ2 (DOCK); 2XCG (DOCK); 2XFN (DOCK); 2XFO (DOCK); 2XFP (DOCK); 2XFQ (DOCK); 2XFU (DOCK); 3PO7 (DOCK); 3ZYX (DOCK); MAOB

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	606	196	53	32
Binding ≤ 1μM	375	127	29	24

Reactome ID	Description	Species
REACT_416	Monoamines are oxidized to aldehydes by MAOA and MAOB, producing NH3 and H2O2	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
AOFA_HUMAN	P21397	CHEMBL1951	Monoamine Oxidase A, Human	243

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
AOFB_BOVIN	P56560	CHEMBL2756	Monoamine Oxidase B, Bovin	130	44	4	1
AOFB_MOUSE	Q8BW75	CHEMBL3050	Monoamine Oxidase B, Mouse	3	2	2	1
AOFB_RAT	P19643	CHEMBL2993	Monoamine Oxidase B, Rat	501	96	19	21

Clustered By Gene (0)

Clustered By Organism (7)

Code	Description	Substances	Purchasable	Natural	In Man
AOFB-1-E	Monoamine Oxidase B (cluster #1 Of 8), Eukaryotic	224	70	18	20
AOFB-2-E	Monoamine Oxidase B (cluster #2 Of 8), Eukaryotic	531	132	22	11
AOFB-3-E	Monoamine Oxidase B (cluster #3 Of 8), Eukaryotic	40	15	2	3
AOFB-4-E	Monoamine Oxidase B (cluster #4 Of 8), Eukaryotic	333	77	18	8
AOFB-5-E	Monoamine Oxidase B (cluster #5 Of 8), Eukaryotic	16	7	0	0
AOFB-6-E	Monoamine Oxidase B (cluster #6 Of 8), Eukaryotic	83	18	9	3
AOFB-7-E	Monoamine Oxidase B (cluster #7 Of 8), Eukaryotic	1	1	1	0
AOFB-8-E	Monoamine Oxidase B (cluster #8 Of 8), Eukaryotic	12	3	0	0

Uniprot	Swissprot	Chembl	Description	Number Shared
AOFA_HUMAN	P21397	CHEMBL1951	Monoamine Oxidase A, Human	243
AOFB_RAT	P19643	CHEMBL2993	Monoamine Oxidase B, Rat	54
AOFA_RAT	P21396	CHEMBL3358	Monoamine Oxidase A, Rat	41
ALDH2_HUMAN	P05091	CHEMBL1935	Aldehyde Dehydrogenase, Human	19
O82865_MICLU	O82865	CHEMBL4529	Tyramine Oxidase, Miclu	16
PPARG_HUMAN	P37231	CHEMBL235	Peroxisome Proliferator-activated Receptor Gamma, Human	8
CP19A_HUMAN	P11511	CHEMBL1978	Cytochrome P450 19A1, Human	7
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	6
AOFA_BOVIN	P21398	CHEMBL3254	Monoamine Oxidase A, Bovin	5
AOFB_BOVIN	P56560	CHEMBL2756	Monoamine Oxidase B, Bovin	5
CISD1_HUMAN	Q9NZ45	CHEMBL1795168	CDGSH Iron-sulfur Domain-containing Protein 1, Human	4
PPARA_HUMAN	Q07869	CHEMBL239	Peroxisome Proliferator-activated Receptor Alpha, Human	4
PPARG_RAT	O88275	CHEMBL4797	Peroxisome Proliferator-activated Receptor Gamma, Rat	4
ACES_HUMAN	P22303	CHEMBL220	Acetylcholinesterase, Human	3
NISCH_HUMAN	Q9Y2I1	CHEMBL3923	Nischarin, Human	3
SGMR1_RAT	Q9R0C9	CHEMBL3602	Sigma Opioid Receptor, Rat	3
AA1R_RAT	P25099	CHEMBL318	Adenosine A1 Receptor, Rat	2
AA2AR_RAT	P30543	CHEMBL302	Adenosine A2a Receptor, Rat	2
ABCG2_HUMAN	Q9UNQ0	CHEMBL5393	ATP-binding Cassette Sub-family G Member 2, Human	2
ADA1A_BOVIN	P18130	CHEMBL4892	Alpha-1a Adrenergic Receptor, Bovin	2
ADA2A_BOVIN	Q28838	CHEMBL4744	Alpha-2a Adrenergic Receptor, Bovin	2
ADA2A_HUMAN	P08913	CHEMBL1867	Alpha-2a Adrenergic Receptor, Human	2
ADA2A_RAT	P22909	CHEMBL327	Alpha-2a Adrenergic Receptor, Rat	2
ADA2B_HUMAN	P18089	CHEMBL1942	Alpha-2b Adrenergic Receptor, Human	2
ADA2B_RAT	P19328	CHEMBL266	Alpha-2b Adrenergic Receptor, Rat	2
ADA2C_HUMAN	P18825	CHEMBL1916	Alpha-2c Adrenergic Receptor, Human	2
ADA2C_RAT	P22086	CHEMBL314	Alpha-2c Adrenergic Receptor, Rat	2
ALDR_HUMAN	P15121	CHEMBL1900	Aldose Reductase, Human	2
AOC2_HUMAN	O75106	CHEMBL4112	Retina-specific Amine Oxidase, Copper Containing, Human	2
AOC3_BOVIN	Q9TTK6	CHEMBL3265	Amine Oxidase, Copper Containing, Bovin	2
CBR1_HUMAN	P16152	CHEMBL5586	Carbonyl Reductase [NADPH] 1, Human	2
CHLE_HUMAN	P06276	CHEMBL1914	Butyrylcholinesterase, Human	2
DHB1_HUMAN	P14061	CHEMBL3181	Estradiol 17-beta-dehydrogenase 1, Human	2
ESR1_HUMAN	P03372	CHEMBL206	Estrogen Receptor Alpha, Human	2
ESR2_HUMAN	Q92731	CHEMBL242	Estrogen Receptor Beta, Human	2
PPARD_HUMAN	Q03181	CHEMBL3979	Peroxisome Proliferator-activated Receptor Delta, Human	2
PPARG_MOUSE	P37238	CHEMBL2459	Peroxisome Proliferator-activated Receptor Gamma, Mouse	2
Q965D7_PLAFA	Q965D7	CHEMBL4512	Fatty Acid Synthase, Plafa	2
RARG_HUMAN	P13631	CHEMBL2003	Retinoic Acid Receptor Gamma, Human	2
RXRA_RAT	Q05343	CHEMBL4431	Retinoid X Receptor Alpha, Rat	2
Z104301	Z104301	CHEMBL1907607	GABA-A Receptor; Anion Channel	2
Z104304	Z104304	CHEMBL1907610	Adrenergic Receptor Alpha-1	2
AA2AR_HUMAN	P29274	CHEMBL251	Adenosine A2a Receptor, Human	1
AA2BR_RAT	P29276	CHEMBL2592	Adenosine A2b Receptor, Rat	1
ABL1_HUMAN	P00519	CHEMBL1862	Tyrosine-protein Kinase ABL, Human	1
ALDH2_RAT	P11884	CHEMBL2812	Aldehyde Dehydrogenase, Rat	1
ALDR_BOVIN	P16116	CHEMBL3081	Aldose Reductase, Bovin	1
AOC3_RAT	O08590	CHEMBL4592	Amine Oxidase, Copper Containing, Rat	1
AOFB_MOUSE	Q8BW75	CHEMBL3050	Monoamine Oxidase B, Mouse	1
B5SU02_9CNID	B5SU02	CHEMBL1075028	Alpha Carbonic Anhydrase, 9cnid	1
C0IX24_9CNID	C0IX24	CHEMBL1649055	Carbonic Anhydrase, 9cnid	1
CAH13_HUMAN	Q8N1Q1	CHEMBL3912	Carbonic Anhydrase XIII, Human	1
CAH14_HUMAN	Q9ULX7	CHEMBL3510	Carbonic Anhydrase XIV, Human	1
CAH15_MOUSE	Q99N23	CHEMBL5973	Carbonic Anhydrase 15, Mouse	1
CAH1_HUMAN	P00915	CHEMBL261	Carbonic Anhydrase I, Human	1
CAH2_HUMAN	P00918	CHEMBL205	Carbonic Anhydrase II, Human	1
CAH4_HUMAN	P22748	CHEMBL3729	Carbonic Anhydrase IV, Human	1
CAH5A_HUMAN	P35218	CHEMBL4789	Carbonic Anhydrase VA, Human	1
CAH5B_HUMAN	Q9Y2D0	CHEMBL3969	Carbonic Anhydrase VB, Human	1
CAH6_HUMAN	P23280	CHEMBL3025	Carbonic Anhydrase VI, Human	1
CAH7_HUMAN	P43166	CHEMBL2326	Carbonic Anhydrase VII, Human	1
CAH9_HUMAN	Q16790	CHEMBL3594	Carbonic Anhydrase IX, Human	1
CAN_YEAST	P53615	CHEMBL5931	Carbonic Anhydrase, Yeast	1
CCNB1_HUMAN	P14635	CHEMBL2412	G2/mitotic-specific Cyclin B1, Human	1
CCNB2_HUMAN	O95067	CHEMBL3723	G2/mitotic-specific Cyclin B2, Human	1
CCNB3_HUMAN	Q8WWL7	CHEMBL3606	G2/mitotic-specific Cyclin B3, Human	1
CDK1_HUMAN	P06493	CHEMBL308	Cyclin-dependent Kinase 1, Human	1
CDK6_HUMAN	Q00534	CHEMBL2508	Cyclin-dependent Kinase 6, Human	1
CP1B1_HUMAN	Q16678	CHEMBL4878	Cytochrome P450 1B1, Human	1
CYNT_HELPY	O24855	CHEMBL4211	Carbonic Anhydrase 1, Helpy	1
CYNT_MYCTU	O53573	CHEMBL6068	Carbonic Anhydrase, Myctu	1
DHB2_HUMAN	P37059	CHEMBL2789	Estradiol 17-beta-dehydrogenase 2, Human	1
DHB3_HUMAN	P37058	CHEMBL4234	Estradiol 17-beta-dehydrogenase 3, Human	1
EGFR_HUMAN	P00533	CHEMBL203	Epidermal Growth Factor Receptor ErbB1, Human	1
ERR1_HUMAN	P11474	CHEMBL3429	Estrogen-related Receptor Alpha, Human	1
ERR2_HUMAN	O95718	CHEMBL3751	Estrogen-related Receptor Beta, Human	1
GBRA1_HUMAN	P14867	CHEMBL1962	GABA Receptor Alpha-1 Subunit, Human	1
GBRA2_HUMAN	P47869	CHEMBL4956	GABA Receptor Alpha-2 Subunit, Human	1
GBRA3_HUMAN	P34903	CHEMBL3026	GABA Receptor Alpha-3 Subunit, Human	1
GBRA4_HUMAN	P48169	CHEMBL2472	GABA Receptor Alpha-4 Subunit, Human	1
GBRA5_HUMAN	P31644	CHEMBL5112	GABA Receptor Alpha-5 Subunit, Human	1
GBRA6_HUMAN	Q16445	CHEMBL2579	GABA Receptor Alpha-6 Subunit, Human	1
GSK3A_HUMAN	P49840	CHEMBL2850	Glycogen Synthase Kinase-3 Alpha, Human	1
GSK3B_HUMAN	P49841	CHEMBL262	Glycogen Synthase Kinase-3 Beta, Human	1
KDM1A_HUMAN	O60341	CHEMBL6136	Lysine-specific Histone Demethylase 1, Human	1
MGA_HUMAN	O43451	CHEMBL2074	Maltase-glucoamylase, Human	1
MK01_HUMAN	P28482	CHEMBL4040	MAP Kinase ERK2, Human	1
OPRD_HUMAN	P41143	CHEMBL236	Delta Opioid Receptor, Human	1
OPRD_RAT	P33533	CHEMBL269	Delta Opioid Receptor, Rat	1
OPRK_CAVPO	P41144	CHEMBL3952	Kappa Opioid Receptor, Guinea Pig	1
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	1
OPRK_RAT	P34975	CHEMBL3614	Kappa Opioid Receptor, Rat	1
OPRM_RAT	P33535	CHEMBL270	Mu Opioid Receptor, Rat	1
P96878_MYCTU	P96878	CHEMBL5767	PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE), Myctu	1
Q3I4V7_CRYNV	Q3I4V7	CHEMBL1697676	Carbonic Anhydrase 2, Crynv	1
Q5AJ71_CANAL	Q5AJ71	CHEMBL5337	Carbonic Anhydrase, Canal	1
Q965D6_PLAFA	Q965D6	CHEMBL4513	3-oxoacyl-acyl-carrier Protein Reductase, Plafa	1
SCN1A_RAT	P04774	CHEMBL4906	Sodium Channel Protein Type I Alpha Subunit, Rat	1
SCN2A_RAT	P04775	CHEMBL3399	Sodium Channel Protein Type II Alpha Subunit, Rat	1
SCN3A_RAT	P08104	CHEMBL4966	Sodium Channel Protein Type III Alpha Subunit, Rat	1
SCN8A_RAT	O88420	CHEMBL2752	Sodium Channel Protein Type VIII Alpha Subunit, Rat	1
XDH_HUMAN	P47989	CHEMBL1929	Xanthine Dehydrogenase, Human	1
Z104294	Z104294	CHEMBL1907600	Cyclin-dependent Kinase 5/CDK5 Activator 1	1