GABA-A Receptor; Anion Channel (2,057 Compounds)


Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 2,057 164 92 47
Binding ≤ 1μM 1,586 123 68 36
Functional ≤ 10μM 70 8 6 4

Reactome Network (0)

Clustered By Gene (0)

Clustered By Organism (7)

Code Description Substances Purchasable Natural In Man
Z104301-1-O GABA-A Receptor; Anion Channel (cluster #1 Of 8), Other 1,363 77 31 24
Z104301-2-O GABA-A Receptor; Anion Channel (cluster #2 Of 8), Other 538 46 32 13
Z104301-3-O GABA-A Receptor; Anion Channel (cluster #3 Of 8), Other 2 1 1 1
Z104301-4-O GABA-A Receptor; Anion Channel (cluster #4 Of 8), Other 105 34 19 4
Z104301-5-O GABA-A Receptor; Anion Channel (cluster #5 Of 8), Other 34 8 12 2
Z104301-6-O GABA-A Receptor; Anion Channel (cluster #6 Of 8), Other 15 6 4 2
Z104301-7-O GABA-A Receptor; Anion Channel (cluster #7 Of 8), Other 12 0 0 0
Z104301-8-O GABA-A Receptor; Anion Channel (cluster #8 Of 8), Other 7 1 1 1
Uniprot Swissprot Chembl Description Number Shared
GBRA1_HUMAN P14867 CHEMBL1962 GABA Receptor Alpha-1 Subunit, Human 121
GBRA3_HUMAN P34903 CHEMBL3026 GABA Receptor Alpha-3 Subunit, Human 105
GBRG2_HUMAN P18507 CHEMBL1788 GABA Receptor Gamma-2 Subunit, Human 104
GBRA5_HUMAN P31644 CHEMBL5112 GABA Receptor Alpha-5 Subunit, Human 94
GBRA2_HUMAN P47869 CHEMBL4956 GABA Receptor Alpha-2 Subunit, Human 93
GBRB3_HUMAN P28472 CHEMBL1847 GABA Receptor Beta-3 Subunit, Human 85
GBRA6_HUMAN Q16445 CHEMBL2579 GABA Receptor Alpha-6 Subunit, Human 62
TSPO_RAT P16257 CHEMBL4552 Peripheral-type Benzodiazepine Receptor, Rat 60
GBRB2_HUMAN P47870 CHEMBL1920 GABA Receptor Beta-2 Subunit, Human 39
GBRA4_HUMAN P48169 CHEMBL2472 GABA Receptor Alpha-4 Subunit, Human 34
GBRG1_RAT P23574 CHEMBL296 GABA Receptor Gamma-1 Subunit, Rat 29
GBRG2_RAT P18508 CHEMBL297 GABA Receptor Gamma-2 Subunit, Rat 29
GBRA2_RAT P23576 CHEMBL341 GABA Receptor Alpha-2 Subunit, Rat 25
GBRB3_RAT P63079 CHEMBL316 GABA Receptor Beta-3 Subunit, Rat 20
GBRA1_RAT P62813 CHEMBL343 GABA Receptor Alpha-1 Subunit, Rat 19
GBRA4_RAT P28471 CHEMBL292 GABA Receptor Alpha-4 Subunit, Rat 18
GBRA5_RAT P19969 CHEMBL300 GABA Receptor Alpha-5 Subunit, Rat 18
GBRB2_RAT P63138 CHEMBL295 GABA Receptor Beta-2 Subunit, Rat 17
GBRA6_RAT P30191 CHEMBL293 GABA Receptor Alpha-6 Subunit, Rat 15
GBRB1_RAT P15431 CHEMBL334 GABA Receptor Beta-1 Subunit, Rat 15
GBRD_RAT P18506 CHEMBL337 GABA Receptor Delta Subunit, Rat 14
GBRE_RAT Q9ES14 CHEMBL306 GABA Receptor Epsilon Subunit, Rat 14
Q91ZM7_RAT Q91ZM7 CHEMBL305 GABA Receptor Theta Subunit, Rat 14
GBRB1_HUMAN P18505 CHEMBL4558 GABA Receptor Beta-1 Subunit, Human 13
GBRD_HUMAN O14764 CHEMBL3591 GABA Receptor Delta Subunit, Human 13
GBRE_HUMAN P78334 CHEMBL4635 GABA Receptor Epsilon Subunit, Human 13
GBRG1_HUMAN Q8N1C3 CHEMBL4044 GABA Receptor Gamma-1 Subunit, Human 13
GBRG3_HUMAN Q99928 CHEMBL2739 GABA Receptor Gamma-3 Subunit, Human 13
GBRG3_RAT P28473 CHEMBL336 GABA Receptor Gamma-3 Subunit, Rat 13
GBRP_HUMAN O00591 CHEMBL3506 GABA Receptor Pi Subunit, Human 13
GABR1_RAT Q9Z0U4 CHEMBL2753 GABA-B Receptor 1, Rat 12
GABR2_RAT O88871 CHEMBL4686 GABA-B Receptor 2, Rat 12
GBRA3_RAT P20236 CHEMBL328 GABA Receptor Alpha-3 Subunit, Rat 12
GBRP_RAT O09028 CHEMBL294 GABA Receptor Pi Subunit, Rat 12
GBRT_HUMAN Q9UN88 CHEMBL2843 GABA Receptor Theta Subunit, Human 12
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 12
GBRA1_BOVIN P08219 CHEMBL3627 GABA Receptor Alpha-1 Subunit, Bovin 11
GBRA2_BOVIN P10063 CHEMBL2321 GABA Receptor Alpha-2 Subunit, Bovin 11
GBRA3_BOVIN P10064 CHEMBL3628 GABA Receptor Alpha-3 Subunit, Bovin 11
GBRA4_BOVIN P20237 CHEMBL3140 GABA Receptor Alpha-4 Subunit, Bovin 11
GBRB1_BOVIN P08220 CHEMBL2848 GABA Receptor Beta-1 Subunit, Bovin 11
GBRG2_BOVIN P22300 CHEMBL5138 GABA Receptor Gamma-2 Subunit, Bovin 11
GLRA1_RAT P07727 CHEMBL3246 Glycine Receptor Alpha-1 Chain, Rat 7
GLRA2_RAT P22771 CHEMBL2328 Glycine Receptor Alpha-2 Chain, Rat 7
GLRA3_RAT P24524 CHEMBL2677 Glycine Receptor Alpha-3 Chain, Rat 7
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 6
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 5
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 5
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 5
Z50594 Z50594 CHEMBL375 Mus Musculus 5
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 4
GABR1_HUMAN Q9UBS5 CHEMBL2064 GABA-B Receptor 1, Human 4
GABR2_HUMAN O75899 CHEMBL5034 GABA-B Receptor 2, Human 4
GBRR1_RAT P50572 CHEMBL3588 GABA Receptor Rho-1 Subunit, Rat 4
ABCG2_HUMAN Q9UNQ0 CHEMBL5393 ATP-binding Cassette Sub-family G Member 2, Human 3
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 3
GBRA1_MOUSE P62812 CHEMBL3139 GABA Receptor Alpha-1 Subunit, Mouse 3
S6A13_RAT P31646 CHEMBL4889 GABA Transporter 2, Rat 3
SC6A1_RAT P23978 CHEMBL4054 GABA Transporter 1, Rat 3
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 2
CBR1_HUMAN P16152 CHEMBL5586 Carbonyl Reductase [NADPH] 1, Human 2
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 2
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 2
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 2
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 2
CDK6_HUMAN Q00534 CHEMBL2508 Cyclin-dependent Kinase 6, Human 2
CP1B1_HUMAN Q16678 CHEMBL4878 Cytochrome P450 1B1, Human 2
DHB1_HUMAN P14061 CHEMBL3181 Estradiol 17-beta-dehydrogenase 1, Human 2
GBRR2_RAT P47742 CHEMBL2953 GABA Receptor Rho-2 Subunit, Rat 2
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 2
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 2
GYRA_ECOLI P0AES4 CHEMBL1858 DNA Gyrase Subunit A, Ecoli 2
GYRB_ECOLI P0AES6 CHEMBL1826 DNA Gyrase Subunit B, Ecoli 2
PARC_STAAU P0C1U9 CHEMBL4088 Topoisomerase IV Subunit A, Staau 2
S6A11_RAT P31647 CHEMBL3598 GABA Transporter 3, Rat 2
S6A12_RAT P48056 CHEMBL5248 Betaine Transporter, Rat 2
XDH_HUMAN P47989 CHEMBL1929 Xanthine Dehydrogenase, Human 2
Z104294 Z104294 CHEMBL1907600 Cyclin-dependent Kinase 5/CDK5 Activator 1 2
Z50512 Z50512 CHEMBL369 Cavia Porcellus 2
5HT1D_PIG P79400 CHEMBL4105 Serotonin 1d (5-HT1d) Receptor, Pig 1
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1
A2AMW3_MOUSE A2AMW3 CHEMBL3121 GABA Receptor Epsilon Subunit, Mouse 1
AA2BR_RAT P29276 CHEMBL2592 Adenosine A2b Receptor, Rat 1
ALDR_BOVIN P16116 CHEMBL3081 Aldose Reductase, Bovin 1
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 1
ALDR_RAT P07943 CHEMBL2622 Aldose Reductase, Rat 1
BACE1_HUMAN P56817 CHEMBL4822 Beta-secretase 1, Human 1
BGLR_RAT P06760 CHEMBL4814 Beta-glucuronidase, Rat 1
CALM_HUMAN P62158 CHEMBL6093 Calmodulin, Human 1
CCKAR_MOUSE O08786 CHEMBL2798 Cholecystokinin A Receptor, Mouse 1
CCKAR_RAT P30551 CHEMBL2871 Cholecystokinin A Receptor, Rat 1
CSK21_HUMAN P68400 CHEMBL3629 Casein Kinase II Alpha, Human 1
CSK2B_HUMAN P67870 CHEMBL2358 Casein Kinase II Beta, Human 1
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1
ESR1_HUMAN P03372 CHEMBL206 Estrogen Receptor Alpha, Human 1
ESR2_HUMAN Q92731 CHEMBL242 Estrogen Receptor Beta, Human 1
FABPL_RAT P02692 CHEMBL5738 Fatty Acid-binding Protein, Liver, Rat 1
GASR_RAT P30553 CHEMBL3508 Cholecystokinin B Receptor, Rat 1
GBRA2_MOUSE P26048 CHEMBL2705 GABA Receptor Alpha-2 Subunit, Mouse 1
GBRA3_MOUSE P26049 CHEMBL3387 GABA Receptor Alpha-3 Subunit, Mouse 1
GBRA4_MOUSE Q9D6F4 CHEMBL4182 GABA Receptor Alpha-4 Subunit, Mouse 1
GBRA5_MOUSE Q8BHJ7 CHEMBL2304 GABA Receptor Alpha-5 Subunit, Mouse 1
GBRA6_MOUSE P16305 CHEMBL4710 GABA Receptor Alpha-6 Subunit, Mouse 1
GBRB1_MOUSE P50571 CHEMBL2839 GABA Receptor Beta-1 Subunit, Mouse 1
GBRB3_MOUSE P63080 CHEMBL4231 GABA Receptor Beta-3 Subunit, Mouse 1
GBRD_MOUSE P22933 CHEMBL3907 GABA Receptor Delta Subunit, Mouse 1
GBRG1_MOUSE Q9R0Y8 CHEMBL2891 GABA Receptor Gamma-1 Subunit, Mouse 1
GBRG2_MOUSE P22723 CHEMBL2941 GABA Receptor Gamma-2 Subunit, Mouse 1
GBRG3_MOUSE P27681 CHEMBL4236 GABA Receptor Gamma-3 Subunit, Mouse 1
GBRP_MOUSE Q8QZW7 CHEMBL2746 GABA Receptor Pi Subunit, Mouse 1
GBRT_MOUSE Q9JLF1 CHEMBL3249 GABA Receptor Theta Subunit, Mouse 1
I23O1_HUMAN P14902 CHEMBL4685 Indoleamine 2,3-dioxygenase, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 1
MRP1_HUMAN P33527 CHEMBL3004 Multidrug Resistance-associated Protein 1, Human 1
NOX4_HUMAN Q9NPH5 CHEMBL1250375 NADPH Oxidase 4, Human 1
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 1
OPRD_PIG P79291 CHEMBL4103 Delta Opioid Receptor, Pig 1
P90584_PLAFA P90584 CHEMBL4090 Protein Kinase Pfmrk, Plafa 1
PDE5A_BOVIN Q28156 CHEMBL3478 Phosphodiesterase 5A, Bovin 1
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 1
Q965D6_PLAFA Q965D6 CHEMBL4513 3-oxoacyl-acyl-carrier Protein Reductase, Plafa 1
REST_BORBU O50979 CHEMBL1667698 Telomere Resolvase ResT, Borbu 1
S6A11_HUMAN P48066 CHEMBL5208 GABA Transporter 3, Human 1
SC6A1_HUMAN P30531 CHEMBL1903 GABA Transporter 1, Human 1
THA_HUMAN P10827 CHEMBL1860 Thyroid Hormone Receptor Alpha, Human 1
THA_RAT P63059 CHEMBL4823 Thyroid Hormone Receptor Alpha, Rat 1
THB_HUMAN P10828 CHEMBL1947 Thyroid Hormone Receptor Beta-1, Human 1
THB_RAT P18113 CHEMBL3917 Thyroid Hormone Receptor Beta-1, Rat 1
TOP2A_HUMAN P11388 CHEMBL1806 DNA Topoisomerase II Alpha, Human 1
TOP2B_HUMAN Q02880 CHEMBL3396 DNA Topoisomerase II Beta, Human 1