UCSF

GABA Receptor Beta-1 Subunit, Bovin (283 Compounds)

Swissprot:
GBRB1_BOVIN
Stitch:
GBRB1_BOVIN
UniProt:
P08220
ChEMBL:
CHEMBL2848
Reactome:
REACT_213858
REACT_220161
PDB:
GABRB1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 283 42 17 5
Binding ≤ 1μM 218 34 14 5
Functional ≤ 10μM 18 0 0 0

Reactome Network (2)

Uniprot Swissprot Chembl Description Number Shared
GBRA1_BOVIN P08219 CHEMBL3627 GABA Receptor Alpha-1 Subunit, Bovin 284
GBRA4_BOVIN P20237 CHEMBL3140 GABA Receptor Alpha-4 Subunit, Bovin 284

Ligand-gated ion channel transport

Uniprot Swissprot Chembl Description Number Shared
GBRA1_BOVIN P08219 CHEMBL3627 GABA Receptor Alpha-1 Subunit, Bovin 284
GBRA4_BOVIN P20237 CHEMBL3140 GABA Receptor Alpha-4 Subunit, Bovin 284
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GBRB1_HUMAN P18505 CHEMBL4558 GABA Receptor Beta-1 Subunit, Human 246 20 11 9
GBRB1_MOUSE P50571 CHEMBL2839 GABA Receptor Beta-1 Subunit, Mouse 37 3 2 2
GBRB1_RAT P15431 CHEMBL334 GABA Receptor Beta-1 Subunit, Rat 124 15 10 6

Clustered By Gene (0)

Clustered By Organism (5)

Code Description Substances Purchasable Natural In Man
GBRB1-1-E GABA Receptor Beta-1 Subunit (cluster #1 Of 6), Eukaryotic 589 48 25 11
GBRB1-2-E GABA Receptor Beta-1 Subunit (cluster #2 Of 6), Eukaryotic 22 4 4 3
GBRB1-3-E GABA Receptor Beta-1 Subunit (cluster #3 Of 6), Eukaryotic 65 13 2 1
GBRB1-4-E GABA Receptor Beta-1 Subunit (cluster #4 Of 6), Eukaryotic 3 0 0 0
GBRB1-5-E GABA Receptor Beta-1 Subunit (cluster #5 Of 6), Eukaryotic 3 3 1 1
GBRB1-6-E GABA Receptor Beta-1 Subunit (cluster #6 Of 6), Eukaryotic 4 4 1 1
Uniprot Swissprot Chembl Description Number Shared
GBRA1_BOVIN P08219 CHEMBL3627 GABA Receptor Alpha-1 Subunit, Bovin 284
GBRA2_BOVIN P10063 CHEMBL2321 GABA Receptor Alpha-2 Subunit, Bovin 284
GBRA3_BOVIN P10064 CHEMBL3628 GABA Receptor Alpha-3 Subunit, Bovin 284
GBRA4_BOVIN P20237 CHEMBL3140 GABA Receptor Alpha-4 Subunit, Bovin 284
GBRG2_BOVIN P22300 CHEMBL5138 GABA Receptor Gamma-2 Subunit, Bovin 284
GBRA2_RAT P23576 CHEMBL341 GABA Receptor Alpha-2 Subunit, Rat 36
GBRA1_RAT P62813 CHEMBL343 GABA Receptor Alpha-1 Subunit, Rat 32
GBRB2_RAT P63138 CHEMBL295 GABA Receptor Beta-2 Subunit, Rat 30
GBRG2_RAT P18508 CHEMBL297 GABA Receptor Gamma-2 Subunit, Rat 30
GBRA5_RAT P19969 CHEMBL300 GABA Receptor Alpha-5 Subunit, Rat 26
GBRB3_RAT P63079 CHEMBL316 GABA Receptor Beta-3 Subunit, Rat 23
TSPO_BOVIN P30535 CHEMBL2419 Peripheral-type Benzodiazepine Receptor, Bovin 18
GBRA3_RAT P20236 CHEMBL328 GABA Receptor Alpha-3 Subunit, Rat 15
AA1R_BOVIN P28190 CHEMBL4975 Adenosine A1 Receptor, Bovin 13
GBRA1_HUMAN P14867 CHEMBL1962 GABA Receptor Alpha-1 Subunit, Human 11
GBRA5_HUMAN P31644 CHEMBL5112 GABA Receptor Alpha-5 Subunit, Human 11
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 11
GBRA2_HUMAN P47869 CHEMBL4956 GABA Receptor Alpha-2 Subunit, Human 10
AA2AR_HUMAN P29274 CHEMBL251 Adenosine A2a Receptor, Human 9
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 9
GBRA3_HUMAN P34903 CHEMBL3026 GABA Receptor Alpha-3 Subunit, Human 8
GBRB3_HUMAN P28472 CHEMBL1847 GABA Receptor Beta-3 Subunit, Human 7
GBRG2_HUMAN P18507 CHEMBL1788 GABA Receptor Gamma-2 Subunit, Human 7
GBRA6_HUMAN Q16445 CHEMBL2579 GABA Receptor Alpha-6 Subunit, Human 6
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 5
GBRA4_HUMAN P48169 CHEMBL2472 GABA Receptor Alpha-4 Subunit, Human 4
GBRA4_RAT P28471 CHEMBL292 GABA Receptor Alpha-4 Subunit, Rat 4
GBRA6_RAT P30191 CHEMBL293 GABA Receptor Alpha-6 Subunit, Rat 4
GBRB2_HUMAN P47870 CHEMBL1920 GABA Receptor Beta-2 Subunit, Human 4
GBRA1_MOUSE P62812 CHEMBL3139 GABA Receptor Alpha-1 Subunit, Mouse 3
GBRB1_HUMAN P18505 CHEMBL4558 GABA Receptor Beta-1 Subunit, Human 3
GBRB1_RAT P15431 CHEMBL334 GABA Receptor Beta-1 Subunit, Rat 3
GBRD_HUMAN O14764 CHEMBL3591 GABA Receptor Delta Subunit, Human 3
GBRD_RAT P18506 CHEMBL337 GABA Receptor Delta Subunit, Rat 3
GBRE_HUMAN P78334 CHEMBL4635 GABA Receptor Epsilon Subunit, Human 3
GBRE_RAT Q9ES14 CHEMBL306 GABA Receptor Epsilon Subunit, Rat 3
GBRG1_HUMAN Q8N1C3 CHEMBL4044 GABA Receptor Gamma-1 Subunit, Human 3
GBRG1_RAT P23574 CHEMBL296 GABA Receptor Gamma-1 Subunit, Rat 3
GBRG3_HUMAN Q99928 CHEMBL2739 GABA Receptor Gamma-3 Subunit, Human 3
GBRP_HUMAN O00591 CHEMBL3506 GABA Receptor Pi Subunit, Human 3
GBRR1_RAT P50572 CHEMBL3588 GABA Receptor Rho-1 Subunit, Rat 3
GBRT_HUMAN Q9UN88 CHEMBL2843 GABA Receptor Theta Subunit, Human 3
Q91ZM7_RAT Q91ZM7 CHEMBL305 GABA Receptor Theta Subunit, Rat 3
GBRP_RAT O09028 CHEMBL294 GABA Receptor Pi Subunit, Rat 2
GBRR2_RAT P47742 CHEMBL2953 GABA Receptor Rho-2 Subunit, Rat 2
TSPO_RAT P16257 CHEMBL4552 Peripheral-type Benzodiazepine Receptor, Rat 2
A2AMW3_MOUSE A2AMW3 CHEMBL3121 GABA Receptor Epsilon Subunit, Mouse 1
FABPL_RAT P02692 CHEMBL5738 Fatty Acid-binding Protein, Liver, Rat 1
GBRA2_MOUSE P26048 CHEMBL2705 GABA Receptor Alpha-2 Subunit, Mouse 1
GBRA3_MOUSE P26049 CHEMBL3387 GABA Receptor Alpha-3 Subunit, Mouse 1
GBRA4_MOUSE Q9D6F4 CHEMBL4182 GABA Receptor Alpha-4 Subunit, Mouse 1
GBRA5_MOUSE Q8BHJ7 CHEMBL2304 GABA Receptor Alpha-5 Subunit, Mouse 1
GBRA6_MOUSE P16305 CHEMBL4710 GABA Receptor Alpha-6 Subunit, Mouse 1
GBRB1_MOUSE P50571 CHEMBL2839 GABA Receptor Beta-1 Subunit, Mouse 1
GBRB3_MOUSE P63080 CHEMBL4231 GABA Receptor Beta-3 Subunit, Mouse 1
GBRD_MOUSE P22933 CHEMBL3907 GABA Receptor Delta Subunit, Mouse 1
GBRG1_MOUSE Q9R0Y8 CHEMBL2891 GABA Receptor Gamma-1 Subunit, Mouse 1
GBRG2_MOUSE P22723 CHEMBL2941 GABA Receptor Gamma-2 Subunit, Mouse 1
GBRG3_MOUSE P27681 CHEMBL4236 GABA Receptor Gamma-3 Subunit, Mouse 1
GBRG3_RAT P28473 CHEMBL336 GABA Receptor Gamma-3 Subunit, Rat 1
GBRP_MOUSE Q8QZW7 CHEMBL2746 GABA Receptor Pi Subunit, Mouse 1
GBRT_MOUSE Q9JLF1 CHEMBL3249 GABA Receptor Theta Subunit, Mouse 1
PDE5A_BOVIN Q28156 CHEMBL3478 Phosphodiesterase 5A, Bovin 1