UCSF

GABA Receptor Alpha-1 Subunit, Rat (207 Compounds)

Swissprot:
GBRA1_RAT
Stitch:
GBRA1_RAT
UniProt:
P62813
ChEMBL:
CHEMBL343
Reactome:
REACT_199021
REACT_199029
PDB:
Gabra1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 207 16 9 6
Binding ≤ 1μM 191 12 7 5
Functional ≤ 10μM 1 1 1 1

Reactome Network (2)

Reactome ID Description Species
REACT_199021 GABA A receptor activation Rattus norvegicus
REACT_199029 Ligand-gated ion channel transport Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
GBRA4_RAT P28471 CHEMBL292 GABA Receptor Alpha-4 Subunit, Rat 120
GBRA5_RAT P19969 CHEMBL300 GABA Receptor Alpha-5 Subunit, Rat 162
GBRB2_RAT P63138 CHEMBL295 GABA Receptor Beta-2 Subunit, Rat 138
GBRG2_RAT P18508 CHEMBL297 GABA Receptor Gamma-2 Subunit, Rat 150
GBRG3_RAT P28473 CHEMBL336 GABA Receptor Gamma-3 Subunit, Rat 80

Ligand-gated ion channel transport

Uniprot Swissprot Chembl Description Number Shared
GBRA4_RAT P28471 CHEMBL292 GABA Receptor Alpha-4 Subunit, Rat 120
GBRA5_RAT P19969 CHEMBL300 GABA Receptor Alpha-5 Subunit, Rat 162
GBRB2_RAT P63138 CHEMBL295 GABA Receptor Beta-2 Subunit, Rat 138
GBRG2_RAT P18508 CHEMBL297 GABA Receptor Gamma-2 Subunit, Rat 150
GBRG3_RAT P28473 CHEMBL336 GABA Receptor Gamma-3 Subunit, Rat 80
GBRR2_RAT P47742 CHEMBL2953 GABA Receptor Rho-2 Subunit, Rat 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GBRA1_BOVIN P08219 CHEMBL3627 GABA Receptor Alpha-1 Subunit, Bovin 302 43 17 5
GBRA1_HUMAN P14867 CHEMBL1962 GABA Receptor Alpha-1 Subunit, Human 959 77 35 22
GBRA1_MOUSE P62812 CHEMBL3139 GABA Receptor Alpha-1 Subunit, Mouse 45 6 5 2
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
GBRA2_RAT P23576 CHEMBL341 GABA Receptor Alpha-2 Subunit, Rat 250 27 18 11
GBRA3_RAT P20236 CHEMBL328 GABA Receptor Alpha-3 Subunit, Rat 159 12 11 7
GBRA4_RAT P28471 CHEMBL292 GABA Receptor Alpha-4 Subunit, Rat 147 11 11 7
GBRA5_RAT P19969 CHEMBL300 GABA Receptor Alpha-5 Subunit, Rat 189 15 11 7
GBRA6_RAT P30191 CHEMBL293 GABA Receptor Alpha-6 Subunit, Rat 146 12 11 7

Clustered By Gene (0)

Clustered By Organism (7)

Code Description Substances Purchasable Natural In Man
GBRA1-1-E GABA Receptor Alpha-1 Subunit (cluster #1 Of 8), Eukaryotic 1,249 78 38 23
GBRA1-2-E GABA Receptor Alpha-1 Subunit (cluster #2 Of 8), Eukaryotic 28 2 2 0
GBRA1-3-E GABA Receptor Alpha-1 Subunit (cluster #3 Of 8), Eukaryotic 33 2 1 1
GBRA1-4-E GABA Receptor Alpha-1 Subunit (cluster #4 Of 8), Eukaryotic 14 0 0 0
GBRA1-5-E GABA Receptor Alpha-1 Subunit (cluster #5 Of 8), Eukaryotic 12 4 1 1
GBRA1-6-E GABA Receptor Alpha-1 Subunit (cluster #6 Of 8), Eukaryotic 134 30 10 0
GBRA1-7-E GABA Receptor Alpha-1 Subunit (cluster #7 Of 8), Eukaryotic 4 4 1 1
GBRA1-8-E GABA Receptor Alpha-1 Subunit (cluster #8 Of 8), Eukaryotic 3 0 0 0
Uniprot Swissprot Chembl Description Number Shared
GBRA5_RAT P19969 CHEMBL300 GABA Receptor Alpha-5 Subunit, Rat 162
GBRA2_RAT P23576 CHEMBL341 GABA Receptor Alpha-2 Subunit, Rat 161
GBRG2_RAT P18508 CHEMBL297 GABA Receptor Gamma-2 Subunit, Rat 150
GBRB2_RAT P63138 CHEMBL295 GABA Receptor Beta-2 Subunit, Rat 138
GBRA3_RAT P20236 CHEMBL328 GABA Receptor Alpha-3 Subunit, Rat 132
GBRA4_RAT P28471 CHEMBL292 GABA Receptor Alpha-4 Subunit, Rat 120
GBRB3_RAT P63079 CHEMBL316 GABA Receptor Beta-3 Subunit, Rat 119
GBRA6_RAT P30191 CHEMBL293 GABA Receptor Alpha-6 Subunit, Rat 114
GBRG1_RAT P23574 CHEMBL296 GABA Receptor Gamma-1 Subunit, Rat 82
GBRG3_RAT P28473 CHEMBL336 GABA Receptor Gamma-3 Subunit, Rat 80
GBRB1_RAT P15431 CHEMBL334 GABA Receptor Beta-1 Subunit, Rat 77
Q91ZM7_RAT Q91ZM7 CHEMBL305 GABA Receptor Theta Subunit, Rat 77
GBRD_RAT P18506 CHEMBL337 GABA Receptor Delta Subunit, Rat 74
GBRE_RAT Q9ES14 CHEMBL306 GABA Receptor Epsilon Subunit, Rat 74
GBRR1_RAT P50572 CHEMBL3588 GABA Receptor Rho-1 Subunit, Rat 68
GBRA1_BOVIN P08219 CHEMBL3627 GABA Receptor Alpha-1 Subunit, Bovin 32
GBRA2_BOVIN P10063 CHEMBL2321 GABA Receptor Alpha-2 Subunit, Bovin 32
GBRA3_BOVIN P10064 CHEMBL3628 GABA Receptor Alpha-3 Subunit, Bovin 32
GBRA4_BOVIN P20237 CHEMBL3140 GABA Receptor Alpha-4 Subunit, Bovin 32
GBRB1_BOVIN P08220 CHEMBL2848 GABA Receptor Beta-1 Subunit, Bovin 32
GBRG2_BOVIN P22300 CHEMBL5138 GABA Receptor Gamma-2 Subunit, Bovin 32
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 19
GBRA1_HUMAN P14867 CHEMBL1962 GABA Receptor Alpha-1 Subunit, Human 16
GBRA2_HUMAN P47869 CHEMBL4956 GABA Receptor Alpha-2 Subunit, Human 14
GBRA3_HUMAN P34903 CHEMBL3026 GABA Receptor Alpha-3 Subunit, Human 14
GBRG2_HUMAN P18507 CHEMBL1788 GABA Receptor Gamma-2 Subunit, Human 14
GBRA5_HUMAN P31644 CHEMBL5112 GABA Receptor Alpha-5 Subunit, Human 13
GBRB2_HUMAN P47870 CHEMBL1920 GABA Receptor Beta-2 Subunit, Human 13
GBRB3_HUMAN P28472 CHEMBL1847 GABA Receptor Beta-3 Subunit, Human 12
GBRA6_HUMAN Q16445 CHEMBL2579 GABA Receptor Alpha-6 Subunit, Human 11
GBRP_RAT O09028 CHEMBL294 GABA Receptor Pi Subunit, Rat 10
GBRA4_HUMAN P48169 CHEMBL2472 GABA Receptor Alpha-4 Subunit, Human 9
GBRB1_HUMAN P18505 CHEMBL4558 GABA Receptor Beta-1 Subunit, Human 8
GBRD_HUMAN O14764 CHEMBL3591 GABA Receptor Delta Subunit, Human 8
GBRE_HUMAN P78334 CHEMBL4635 GABA Receptor Epsilon Subunit, Human 8
GBRG1_HUMAN Q8N1C3 CHEMBL4044 GABA Receptor Gamma-1 Subunit, Human 8
GBRG3_HUMAN Q99928 CHEMBL2739 GABA Receptor Gamma-3 Subunit, Human 8
GBRP_HUMAN O00591 CHEMBL3506 GABA Receptor Pi Subunit, Human 8
GBRT_HUMAN Q9UN88 CHEMBL2843 GABA Receptor Theta Subunit, Human 8
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 4
AA1R_HUMAN P30542 CHEMBL226 Adenosine A1 Receptor, Human 3
GBRA1_MOUSE P62812 CHEMBL3139 GABA Receptor Alpha-1 Subunit, Mouse 2
TSPO_RAT P16257 CHEMBL4552 Peripheral-type Benzodiazepine Receptor, Rat 2
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 2
A2AMW3_MOUSE A2AMW3 CHEMBL3121 GABA Receptor Epsilon Subunit, Mouse 1
FABPL_RAT P02692 CHEMBL5738 Fatty Acid-binding Protein, Liver, Rat 1
GABR1_HUMAN Q9UBS5 CHEMBL2064 GABA-B Receptor 1, Human 1
GABR1_RAT Q9Z0U4 CHEMBL2753 GABA-B Receptor 1, Rat 1
GABR2_HUMAN O75899 CHEMBL5034 GABA-B Receptor 2, Human 1
GABR2_RAT O88871 CHEMBL4686 GABA-B Receptor 2, Rat 1
GBRA2_MOUSE P26048 CHEMBL2705 GABA Receptor Alpha-2 Subunit, Mouse 1
GBRA3_MOUSE P26049 CHEMBL3387 GABA Receptor Alpha-3 Subunit, Mouse 1
GBRA4_MOUSE Q9D6F4 CHEMBL4182 GABA Receptor Alpha-4 Subunit, Mouse 1
GBRA5_MOUSE Q8BHJ7 CHEMBL2304 GABA Receptor Alpha-5 Subunit, Mouse 1
GBRA6_MOUSE P16305 CHEMBL4710 GABA Receptor Alpha-6 Subunit, Mouse 1
GBRB1_MOUSE P50571 CHEMBL2839 GABA Receptor Beta-1 Subunit, Mouse 1
GBRB3_MOUSE P63080 CHEMBL4231 GABA Receptor Beta-3 Subunit, Mouse 1
GBRD_MOUSE P22933 CHEMBL3907 GABA Receptor Delta Subunit, Mouse 1
GBRG1_MOUSE Q9R0Y8 CHEMBL2891 GABA Receptor Gamma-1 Subunit, Mouse 1
GBRG2_MOUSE P22723 CHEMBL2941 GABA Receptor Gamma-2 Subunit, Mouse 1
GBRG3_MOUSE P27681 CHEMBL4236 GABA Receptor Gamma-3 Subunit, Mouse 1
GBRP_MOUSE Q8QZW7 CHEMBL2746 GABA Receptor Pi Subunit, Mouse 1
GBRR2_RAT P47742 CHEMBL2953 GABA Receptor Rho-2 Subunit, Rat 1
GBRT_MOUSE Q9JLF1 CHEMBL3249 GABA Receptor Theta Subunit, Mouse 1
I23O1_HUMAN P14902 CHEMBL4685 Indoleamine 2,3-dioxygenase, Human 1
S6A11_HUMAN P48066 CHEMBL5208 GABA Transporter 3, Human 1
S6A13_RAT P31646 CHEMBL4889 GABA Transporter 2, Rat 1
SC6A1_HUMAN P30531 CHEMBL1903 GABA Transporter 1, Human 1
SC6A1_RAT P23978 CHEMBL4054 GABA Transporter 1, Rat 1