UCSF

Carbonyl Reductase [NADPH] 1, Human (13 Compounds)

Swissprot:
CBR1_HUMAN
Stitch:
CBR1_HUMAN
UniProt:
P16152
ChEMBL:
CHEMBL5586
Reactome:
REACT_150149
PDB:
1WMA (DOCK)
2PFG (DOCK)
3BHI (DOCK)
3BHJ (DOCK)
3BHM (DOCK)
CBR1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 13 6 6 2
Binding ≤ 1μM 7 4 4 1

Reactome Network (1)

Reactome ID Description Species
REACT_150149 Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 1

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
CBR1-1-E Carbonyl Reductase [NADPH] 1 (cluster #1 Of 2), Eukaryotic 12 5 5 1
CBR1-2-E Carbonyl Reductase [NADPH] 1 (cluster #2 Of 2), Eukaryotic 1 1 1 1
Uniprot Swissprot Chembl Description Number Shared
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 3
AOFA_HUMAN P21397 CHEMBL1951 Monoamine Oxidase A, Human 2
AOFB_HUMAN P27338 CHEMBL2039 Monoamine Oxidase B, Human 2
CP1B1_HUMAN Q16678 CHEMBL4878 Cytochrome P450 1B1, Human 2
Z104301 Z104301 CHEMBL1907607 GABA-A Receptor; Anion Channel 2
ABCG2_HUMAN Q9UNQ0 CHEMBL5393 ATP-binding Cassette Sub-family G Member 2, Human 1
ALDR_BOVIN P16116 CHEMBL3081 Aldose Reductase, Bovin 1
ALDR_HUMAN P15121 CHEMBL1900 Aldose Reductase, Human 1
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 1
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 1
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 1
CDK6_HUMAN Q00534 CHEMBL2508 Cyclin-dependent Kinase 6, Human 1
DHB1_HUMAN P14061 CHEMBL3181 Estradiol 17-beta-dehydrogenase 1, Human 1
DHB2_HUMAN P37059 CHEMBL2789 Estradiol 17-beta-dehydrogenase 2, Human 1
FABI_BACSU P54616 CHEMBL1075044 Enoyl-[acyl-carrier-protein] Reductase [NADH], Bacsu 1
FABI_ECOLI P0AEK4 CHEMBL1857 Enoyl-[acyl-carrier-protein] Reductase, Ecoli 1
FABI_STAAR Q6GI75 CHEMBL3994 Enoyl-[acyl-carrier-protein] Reductase, Staar 1
GBRA1_HUMAN P14867 CHEMBL1962 GABA Receptor Alpha-1 Subunit, Human 1
GBRA2_HUMAN P47869 CHEMBL4956 GABA Receptor Alpha-2 Subunit, Human 1
GBRA3_HUMAN P34903 CHEMBL3026 GABA Receptor Alpha-3 Subunit, Human 1
GBRA4_HUMAN P48169 CHEMBL2472 GABA Receptor Alpha-4 Subunit, Human 1
GBRA5_HUMAN P31644 CHEMBL5112 GABA Receptor Alpha-5 Subunit, Human 1
GBRA6_HUMAN Q16445 CHEMBL2579 GABA Receptor Alpha-6 Subunit, Human 1
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 1
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 1
HS90A_HUMAN P07900 CHEMBL3880 Heat Shock Protein HSP 90-alpha, Human 1
HS90B_HUMAN P08238 CHEMBL4303 Heat Shock Protein HSP 90-beta, Human 1
HSC82_YEAST P15108 CHEMBL4199 Heat Shock Protein HSP 90 (HSC82), Yeast 1
HSP82_YEAST P02829 CHEMBL3536 Heat Shock Protein HSP 90 (HSP82), Yeast 1
INHA_MYCTU P0A5Y6 CHEMBL1849 Enoyl-[acyl-carrier-protein] Reductase, Myctu 1
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 1
MRP1_HUMAN P33527 CHEMBL3004 Multidrug Resistance-associated Protein 1, Human 1
PGH2_HUMAN P35354 CHEMBL230 Cyclooxygenase-2, Human 1
Q6UCJ9_TOXGO Q6UCJ9 CHEMBL1250368 Enoyl-acyl Carrier Reductase, Toxgo 1
Q965D5_PLAFA Q965D5 CHEMBL4150 Enoyl-acyl-carrier Protein Reductase, Plafa 1
Q965D6_PLAFA Q965D6 CHEMBL4513 3-oxoacyl-acyl-carrier Protein Reductase, Plafa 1
Q965D7_PLAFA Q965D7 CHEMBL4512 Fatty Acid Synthase, Plafa 1
Q9BJJ9_PLAFA Q9BJJ9 CHEMBL1275211 Enoyl-ACP Reductase, Plafa 1
REST_BORBU O50979 CHEMBL1667698 Telomere Resolvase ResT, Borbu 1
SRC_RAT Q9WUD9 CHEMBL3014 Tyrosine-protein Kinase SRC, Rat 1
XDH_HUMAN P47989 CHEMBL1929 Xanthine Dehydrogenase, Human 1
Z104294 Z104294 CHEMBL1907600 Cyclin-dependent Kinase 5/CDK5 Activator 1 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1