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ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (656)
Reactome (3)
Related By:
Pathway (4)
Organism (1)
Gene (0)
Org. Clust. (1)
ChEMBL (19)
Rings (24)

Peroxisome Proliferator-activated Receptor Delta, Human (656 Compounds)

Swissprot:: PPARD_HUMAN
Stitch:: PPARD_HUMAN
UniProt:: Q03181
ChEMBL:: CHEMBL3979
Reactome:: REACT_11082; REACT_15525; REACT_12528
PDB:: 1GWX (DOCK); 1Y0S (DOCK); 2AWH (DOCK); 2B50 (DOCK); 2BAW (DOCK); 2ENV (DOCK); 2GWX (DOCK); 2J14 (DOCK); 2Q5G (DOCK); 2XYJ (DOCK); 2XYW (DOCK); 2XYX (DOCK); 2ZNP (DOCK); 2ZNQ (DOCK); 3D5F (DOCK); 3DY6 (DOCK); 3ET2 (DOCK); 3GWX (DOCK); 3GZ9 (DOCK); 3OZ0 (DOCK); 3PEQ (DOCK); 3SP9 (DOCK); PPARD

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	656	13	6	12
Binding ≤ 1μM	482	6	1	5
Functional ≤ 10μM	753	7	3	8

Reactome ID	Description	Species
REACT_11082	Import of palmitoyl-CoA into the mitochondrial matrix	Homo sapiens
REACT_15525	Nuclear Receptor transcription pathway	Homo sapiens
REACT_12528	Regulation of pyruvate dehydrogenase (PDH) complex	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
NR1H2_HUMAN	P55055	CHEMBL4093	LXR-beta, Human	21
PPARA_HUMAN	Q07869	CHEMBL239	Peroxisome Proliferator-activated Receptor Alpha, Human	902
PPARG_HUMAN	P37231	CHEMBL235	Peroxisome Proliferator-activated Receptor Gamma, Human	700
RARG_HUMAN	P13631	CHEMBL2003	Retinoic Acid Receptor Gamma, Human	2

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
PPARD_MOUSE	P35396	CHEMBL2458	Peroxisome Proliferator-activated Receptor Delta, Mouse	7	3	3	1

Clustered By Gene (0)

Clustered By Organism (1)

Code	Description	Substances	Purchasable	Natural	In Man
PPARD-1-E	Peroxisome Proliferator-activated Receptor Delta (cluster #1 Of 2), Eukaryotic	96	2	3	2
PPARD-2-E	Peroxisome Proliferator-activated Receptor Delta (cluster #2 Of 2), Eukaryotic	565	11	4	10

Uniprot	Swissprot	Chembl	Description	Number Shared
PPARA_HUMAN	Q07869	CHEMBL239	Peroxisome Proliferator-activated Receptor Alpha, Human	902
PPARG_HUMAN	P37231	CHEMBL235	Peroxisome Proliferator-activated Receptor Gamma, Human	695
PPARG_MOUSE	P37238	CHEMBL2459	Peroxisome Proliferator-activated Receptor Gamma, Mouse	122
PPARG_RAT	O88275	CHEMBL4797	Peroxisome Proliferator-activated Receptor Gamma, Rat	56
PPARD_MOUSE	P35396	CHEMBL2458	Peroxisome Proliferator-activated Receptor Delta, Mouse	29
PPARA_MOUSE	P23204	CHEMBL2128	Peroxisome Proliferator-activated Receptor Alpha, Mouse	24
NR1H2_HUMAN	P55055	CHEMBL4093	LXR-beta, Human	21
NR1H3_HUMAN	Q13133	CHEMBL2808	LXR-alpha, Human	21
Z80169	Z80169	CHEMBL614039	Huh-7 (Hepatocellular Carcinoma)	10
PPARA_CANFA	Q95N78	CHEMBL2847	Peroxisome Proliferator-activated Receptor Alpha, Canine	8
PPARA_RAT	P37230	CHEMBL2129	Peroxisome Proliferator-activated Receptor Alpha, Rat	8
Z80548	Z80548	CHEMBL614245	THP-1 (Acute Monocytic Leukemia Cells)	4
AOFB_HUMAN	P27338	CHEMBL2039	Monoamine Oxidase B, Human	2
RARG_HUMAN	P13631	CHEMBL2003	Retinoic Acid Receptor Gamma, Human	2
RXRA_RAT	Q05343	CHEMBL4431	Retinoid X Receptor Alpha, Rat	2
Z80178	Z80178	CHEMBL614040	J774.A1 (Macrophage Cells)	1
Z81020	Z81020	CHEMBL395	HepG2 (Hepatoblastoma Cells)	1
Z81135	Z81135	CHEMBL614793	L6 (Skeletal Muscle Myoblast Cells)	1
Z81244	Z81244	CHEMBL614123	J774 (Macrophage Cells)	1

Synonyms
Compounds (656)
Related By:
Pathway (4)
Organism (1)
Gene (0)
ChEMBL (19)
Org. Clust. (1)
Rings (24)