UCSF
Image of 1,2,3,4-tetrahydroisoquinoline

Identity 99% 90% 80% 70% Substructure

1,2,3,4-tetrahydroisoquinoline

PubMed — Wikipedia — Google

Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
2 1 10 9 1 0 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 19 20,037 217 988 9 2012-03-06

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 66 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 64 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP8_HUMAN P22894 CHEMBL4588 Matrix Metalloproteinase 8, Human 64 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 62 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 61 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP8_HUMAN P22894 CHEMBL4588 Matrix Metalloproteinase 8, Human 58 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 58 Annotations Catalogs SMILES SDF Mol2 Flexibase
MMP3_HUMAN P08254 CHEMBL283 Matrix Metalloproteinase 3, Human 47 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_CAVPO P97266 CHEMBL4354 Mu Opioid Receptor, Guinea Pig 27 Annotations Catalogs SMILES SDF Mol2 Flexibase
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 12 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPP4_HUMAN P27487 CHEMBL284 Dipeptidyl Peptidase IV, Human 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 10 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPP4_HUMAN P27487 CHEMBL284 Dipeptidyl Peptidase IV, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
ITA3_HUMAN P26006 CHEMBL3525 Integrin Alpha-3, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
ITB3_HUMAN P05106 CHEMBL207 Integrin Beta-3, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPP8_HUMAN Q6V1X1 CHEMBL4657 Dipeptidyl Peptidase VIII, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
PNMT_BOVIN P10938 CHEMBL2331 Phenylethanolamine N-methyltransferase, Bovin 6 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
FA10_HUMAN P00742 CHEMBL244 Coagulation Factor X, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
OXYR_HUMAN P30559 CHEMBL2049 Oxytocin Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
PNMT_BOVIN P10938 CHEMBL2331 Phenylethanolamine N-methyltransferase, Bovin 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
PNMT_HUMAN P11086 CHEMBL4617 Phenylethanolamine N-methyltransferase, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
V1AR_HUMAN P37288 CHEMBL1889 Vasopressin V1a Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
TRY1_HUMAN P07477 CHEMBL209 Trypsin I, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
TRY2_HUMAN P07478 CHEMBL3159 Trypsin II, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
BCL2_HUMAN P10415 CHEMBL4860 Apoptosis Regulator Bcl-2, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
BCL2_HUMAN P10415 CHEMBL4860 Apoptosis Regulator Bcl-2, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ENV_HV1Y2 P35961 CHEMBL6180 Envelope Glycoprotein Gp160, Hv1y2 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
MRCKA_HUMAN Q5VT25 CHEMBL4516 Serine/threonine-protein Kinase MRCK-A, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_PIG P79291 CHEMBL4103 Delta Opioid Receptor, Pig 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRD_PIG P79291 CHEMBL4103 Delta Opioid Receptor, Pig 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PNMT_HUMAN P11086 CHEMBL4617 Phenylethanolamine N-methyltransferase, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARA_HUMAN Q07869 CHEMBL239 Peroxisome Proliferator-activated Receptor Alpha, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARD_HUMAN Q03181 CHEMBL3979 Peroxisome Proliferator-activated Receptor Delta, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARD_HUMAN Q03181 CHEMBL3979 Peroxisome Proliferator-activated Receptor Delta, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PPARG_HUMAN P37231 CHEMBL235 Peroxisome Proliferator-activated Receptor Gamma, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
SOAT1_RAT O70536 CHEMBL285 Acyl Coenzyme A:cholesterol Acyltransferase 1, Rat 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
THRB_HUMAN P00734 CHEMBL204 Thrombin, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
TRY2_HUMAN P07478 CHEMBL3159 Trypsin II, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50512 Z50512 CHEMBL369 Cavia Porcellus 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50594 Z50594 CHEMBL375 Mus Musculus 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACES_HUMAN P22303 CHEMBL220 Acetylcholinesterase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ACES_TORCA P04058 CHEMBL4780 Acetylcholinesterase, Torca 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADRB1_RAT P18090 CHEMBL3252 Beta-1 Adrenergic Receptor, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase