ZINC 12

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Swissprot:: DPP4_HUMAN
Stitch:: DPP4_HUMAN
UniProt:: P27487
ChEMBL:: CHEMBL284
Reactome:: REACT_24019; REACT_23824
PDB:: 1J2E (DOCK); 1N1M (DOCK); 1NU6 (DOCK); 1NU8 (DOCK); 1PFQ (DOCK); 1R9M (DOCK); 1R9N (DOCK); 1RWQ (DOCK); 1TK3 (DOCK); 1TKR (DOCK); 1U8E (DOCK); 1W1I (DOCK); 1WCY (DOCK); 1X70 (DOCK); 2AJL (DOCK); 2BGN (DOCK); 2BGR (DOCK); 2BUB (DOCK); 2FJP (DOCK); 2G5P (DOCK); 2G5T (DOCK); 2G63 (DOCK); 2HHA (DOCK); 2I03 (DOCK); 2I78 (DOCK); 2IIT (DOCK); 2IIV (DOCK); 2JID (DOCK); 2OAG (DOCK); 2OGZ (DOCK); 2OLE (DOCK); 2ONC (DOCK); 2OPH (DOCK); 2OQI (DOCK); 2OQV (DOCK); 2P8S (DOCK); 2QJR (DOCK); 2QKY (DOCK); 2QOE (DOCK); 2QT9 (DOCK); 2QTB (DOCK); 2RGU (DOCK); 2RIP (DOCK); 3BJM (DOCK); 3C43 (DOCK); 3C45 (DOCK); 3CCB (DOCK); 3CCC (DOCK); 3D4L (DOCK); 3EIO (DOCK); 3F8S (DOCK); 3G0B (DOCK); 3G0C (DOCK); 3G0D (DOCK); 3G0G (DOCK); 3H0C (DOCK); 3HAB (DOCK); 3HAC (DOCK); 3KWF (DOCK); 3KWJ (DOCK); 3NOX (DOCK); 3O95 (DOCK); 3O9V (DOCK); 3OC0 (DOCK); 3OPM (DOCK); 3Q8W (DOCK); 3QBJ (DOCK); 3SWW (DOCK); 3SX4 (DOCK); DPP4

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	2,944	39	7	35
Binding ≤ 1μM	2,554	21	7	34
Functional ≤ 10μM	29	2	0	1

Reactome ID	Description	Species
REACT_24019	Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)	Homo sapiens
REACT_23824	Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polyp	Homo sapiens

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
DPP4_MOUSE	P28843	CHEMBL3883	Dipeptidyl Peptidase IV, Mouse	73	1	1	1
DPP4_PIG	P22411	CHEMBL3813	Dipeptidyl Peptidase IV, Pig	117	2	0	2
DPP4_RAT	P14740	CHEMBL4653	Dipeptidyl Peptidase IV, Rat	243	6	1	4

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
DPP2_HUMAN	Q9UHL4	CHEMBL3976	Dipeptidyl Peptidase II, Human	509	5	1	3
DPP8_HUMAN	Q6V1X1	CHEMBL4657	Dipeptidyl Peptidase VIII, Human	435	12	2	6
DPP9_HUMAN	Q86TI2	CHEMBL4793	Dipeptidyl Peptidase IX, Human	215	7	2	5

Code	Description	Substances	Purchasable	Natural	In Man
DPP4-1-E	Dipeptidyl Peptidase IV (cluster #1 Of 3), Eukaryotic	2,211	10	5	32
DPP4-2-E	Dipeptidyl Peptidase IV (cluster #2 Of 3), Eukaryotic	1,034	37	1	9
DPP4-3-E	Dipeptidyl Peptidase IV (cluster #3 Of 3), Eukaryotic	15	0	0	0

Uniprot	Swissprot	Chembl	Description	Number Shared
DPP2_HUMAN	Q9UHL4	CHEMBL3976	Dipeptidyl Peptidase II, Human	363
DPP8_HUMAN	Q6V1X1	CHEMBL4657	Dipeptidyl Peptidase VIII, Human	363
DPP9_HUMAN	Q86TI2	CHEMBL4793	Dipeptidyl Peptidase IX, Human	191
DPP4_RAT	P14740	CHEMBL4653	Dipeptidyl Peptidase IV, Rat	117
DPP4_MOUSE	P28843	CHEMBL3883	Dipeptidyl Peptidase IV, Mouse	73
SEPR_HUMAN	Q12884	CHEMBL4683	Fibroblast Activation Protein Alpha, Human	26
PPCE_HUMAN	P48147	CHEMBL3202	Prolyl Endopeptidase, Human	24
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	22
ACM1_HUMAN	P11229	CHEMBL216	Muscarinic Acetylcholine Receptor M1, Human	16
DPP4_PIG	P22411	CHEMBL3813	Dipeptidyl Peptidase IV, Pig	14
DPP2_RAT	Q9EPB1	CHEMBL4352	Dipeptidyl Peptidase II, Rat	8