UCSF
Image of 4(1H)-pyrimidone

Identity 99% 90% 80% 70% Substructure

4(1H)-pyrimidone

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Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
1 1 7 4 2 1 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 73 61,447 252 1,164 2 2012-03-06

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
GRM1_HUMAN Q13255 CHEMBL3772 Metabotropic Glutamate Receptor 1, Human 52 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM1_RAT P23385 CHEMBL4477 Metabotropic Glutamate Receptor 1, Rat 47 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM1_RAT P23385 CHEMBL4477 Metabotropic Glutamate Receptor 1, Rat 46 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50607 Z50607 CHEMBL378 Human Immunodeficiency Virus 1 41 Annotations Catalogs SMILES SDF Mol2 Flexibase
PNPH_BOVIN P55859 CHEMBL2935 Purine Nucleoside Phosphorylase, Bovin 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
PNPH_BOVIN P55859 CHEMBL2935 Purine Nucleoside Phosphorylase, Bovin 31 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 25 Annotations Catalogs SMILES SDF Mol2 Flexibase
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
ROCK2_HUMAN O75116 CHEMBL2973 Rho-associated Protein Kinase 2, Human 18 Annotations Catalogs SMILES SDF Mol2 Flexibase
TRPV1_HUMAN Q8NER1 CHEMBL4794 Vanilloid Receptor, Human 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
TYSY_HUMAN P04818 CHEMBL1952 Thymidylate Synthase, Human 14 Annotations Catalogs SMILES SDF Mol2 Flexibase
PNPH_HUMAN P00491 CHEMBL4338 Purine Nucleoside Phosphorylase, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
PNPH_HUMAN P00491 CHEMBL4338 Purine Nucleoside Phosphorylase, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
V1BR_HUMAN P47901 CHEMBL1921 Vasopressin V1b Receptor, Human 11 Annotations Catalogs SMILES SDF Mol2 Flexibase
NMDE4_RAT Q62645 CHEMBL303 Glutamate [NMDA] Receptor Subunit Epsilon 4, Rat 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
NMDZ1_RAT P35439 CHEMBL330 Glutamate (NMDA) Receptor Subunit Zeta 1, Rat 9 Annotations Catalogs SMILES SDF Mol2 Flexibase
TYSY_HUMAN P04818 CHEMBL1952 Thymidylate Synthase, Human 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
V1BR_HUMAN P47901 CHEMBL1921 Vasopressin V1b Receptor, Human 8 Annotations Catalogs SMILES SDF Mol2 Flexibase
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM1_RAT P23385 CHEMBL4477 Metabotropic Glutamate Receptor 1, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_RAT P31424 CHEMBL2564 Metabotropic Glutamate Receptor 5, Rat 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
PAFA_HUMAN Q13093 CHEMBL3514 LDL-associated Phospholipase A2, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8JXU8_9HEPC Q8JXU8 CHEMBL5375 Hepatitis C Virus NS5B RNA-dependent RNA Polymerase, 9hepc 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRTS_TOXGO Q07422 CHEMBL2425 Dihydrofolate Reductase, Toxgo 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
DYR_HUMAN P00374 CHEMBL202 Dihydrofolate Reductase, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
KITH_HHV1S P06479 CHEMBL1820 Thymidine Kinase, Hhv1s 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8JXU8_9HEPC Q8JXU8 CHEMBL5375 Hepatitis C Virus NS5B RNA-dependent RNA Polymerase, 9hepc 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
RIR1_MOUSE P07742 CHEMBL3739 Ribonucleoside-diphosphate Reductase M1 Chain, Mouse 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
RIR2_MOUSE P11157 CHEMBL3527 Ribonucleoside-diphosphate Reductase M2 Chain, Mouse 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPP4_HUMAN P27487 CHEMBL284 Dipeptidyl Peptidase IV, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
DPP4_HUMAN P27487 CHEMBL284 Dipeptidyl Peptidase IV, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
DYR_HUMAN P00374 CHEMBL202 Dihydrofolate Reductase, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q72547_9HIV1 Q72547 CHEMBL247 Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q72547_9HIV1 Q72547 CHEMBL247 Human Immunodeficiency Virus Type 1 Reverse Transcriptase, 9hiv1 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
TYPH_HUMAN P19971 CHEMBL3106 Thymidine Phosphorylase, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50643 Z50643 CHEMBL379 Hepatitis C Virus 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
AOFA_RAT P21396 CHEMBL3358 Monoamine Oxidase A, Rat 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
AOFA_RAT P21396 CHEMBL3358 Monoamine Oxidase A, Rat 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
AOFB_RAT P19643 CHEMBL2993 Monoamine Oxidase B, Rat 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
DRTS_TOXGO Q07422 CHEMBL2425 Dihydrofolate Reductase, Toxgo 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
E2QDN0_ECOLX E2QDN0 CHEMBL1795153 Thymidylate Synthase (EC 2.1.1.45) (TS) (TSase), Ecolx 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
E2QDN0_ECOLX E2QDN0 CHEMBL1795153 Thymidylate Synthase (EC 2.1.1.45) (TS) (TSase), Ecolx 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_RAT P31424 CHEMBL2564 Metabotropic Glutamate Receptor 5, Rat 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
PAFA_HUMAN Q13093 CHEMBL3514 LDL-associated Phospholipase A2, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
TYSY_ECOLI P0A884 CHEMBL2555 Thymidylate Synthase, Ecoli 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
TYSY_ECOLI P0A884 CHEMBL2555 Thymidylate Synthase, Ecoli 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
XDH_RAT P22985 CHEMBL1075246 Xanthine Dehydrogenase/oxidase, Rat 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80064 Z80064 CHEMBL382 CCRF-CEM (T-cell Leukemia) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80874 Z80874 CHEMBL393 CEM (T-cell Leukemia) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2BR_HUMAN P29275 CHEMBL255 Adenosine A2b Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
AA2BR_HUMAN P29275 CHEMBL255 Adenosine A2b Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ADRB3_HUMAN P13945 CHEMBL246 Beta-3 Adrenergic Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDN1A_HUMAN P38936 CHEMBL5021 CDK-interacting Protein 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
DYR_ECOLI P0ABQ4 CHEMBL1809 Dihydrofolate Reductase, Ecoli 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
E1BN64_BOVIN E1BN64 CHEMBL5129 Phosphodiesterase 3B, Bovin 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
E1BN64_BOVIN E1BN64 CHEMBL5129 Phosphodiesterase 3B, Bovin 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRIA1_RAT P19490 CHEMBL3753 Glutamate Receptor Ionotropic, AMPA 1, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_HUMAN P41594 CHEMBL3227 Metabotropic Glutamate Receptor 5, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
GRM5_RAT P31424 CHEMBL2564 Metabotropic Glutamate Receptor 5, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
HCAR2_HUMAN Q8TDS4 CHEMBL3785 Nicotinic Acid Receptor 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
IF4E_RABIT P29338 CHEMBL5636 Eukaryotic Translation Initiation Factor 4E, Rabit 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
IF4E_RABIT P29338 CHEMBL5636 Eukaryotic Translation Initiation Factor 4E, Rabit 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
LOX5_HUMAN P09917 CHEMBL215 Arachidonate 5-lipoxygenase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MP2K1_HUMAN Q02750 CHEMBL3587 Dual Specificity Mitogen-activated Protein Kinase Kinase 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
NMDE1_RAT Q00959 CHEMBL310 Glutamate [NMDA] Receptor Subunit Epsilon 1, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PARP1_HUMAN P09874 CHEMBL3105 Poly [ADP-ribose] Polymerase-1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PARP1_MOUSE P11103 CHEMBL3740 Poly [ADP-ribose] Polymerase-1, Mouse 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PARP1_MOUSE P11103 CHEMBL3740 Poly [ADP-ribose] Polymerase-1, Mouse 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PARP2_MOUSE O88554 CHEMBL2794 Poly [ADP-ribose] Polymerase-2, Mouse 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PARP2_MOUSE O88554 CHEMBL2794 Poly [ADP-ribose] Polymerase-2, Mouse 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE3A_HUMAN Q14432 CHEMBL241 Phosphodiesterase 3A, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PDE3B_HUMAN Q13370 CHEMBL290 Phosphodiesterase 3B, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CB_HUMAN P42338 CHEMBL3145 PI3-kinase P110-beta Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CD_HUMAN O00329 CHEMBL3130 PI3-kinase P110-delta Subunit, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
POLG_HCV1 P26664 CHEMBL4620 Hepatitis C Virus Polyprotein, Hcv1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
POLG_HCV1 P26664 CHEMBL4620 Hepatitis C Virus Polyprotein, Hcv1 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q4U254_9ENTO Q4U254 CHEMBL2857 Human Rhinovirus A Protease, 9ento 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q4U254_9ENTO Q4U254 CHEMBL2857 Human Rhinovirus A Protease, 9ento 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8CFB8_MOUSE Q8CFB8 CHEMBL3292 ADP-ribosyltransferase, Mouse 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8CFB8_MOUSE Q8CFB8 CHEMBL3292 ADP-ribosyltransferase, Mouse 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Q8JXU8_9HEPC Q8JXU8 CHEMBL5375 Hepatitis C Virus NS5B RNA-dependent RNA Polymerase, 9hepc 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
RNH1_HUMAN O60930 CHEMBL5893 Ribonuclease H1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
SOAT1_MOUSE Q61263 CHEMBL4464 Acyl Coenzyme A:cholesterol Acyltransferase 1, Mouse 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
SOAT1_RAT O70536 CHEMBL285 Acyl Coenzyme A:cholesterol Acyltransferase 1, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
SOAT2_MOUSE O88908 CHEMBL2653 Acyl Coenzyme A:cholesterol Acyltransferase 2, Mouse 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
SOAT2_RAT Q7TQM4 CHEMBL2856 Acyl Coenzyme A:cholesterol Acyltransferase 2, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
THER_BACTH P00800 CHEMBL3392 Thermolysin, Bacth 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
XDH_BOVIN P80457 CHEMBL3649 Xanthine Dehydrogenase, Bovin 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z103203 Z103203 CHEMBL1075388 A375 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50515 Z50515 CHEMBL370 Human Herpesvirus 2 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z50527 Z50527 CHEMBL613132 Human Herpesvirus 3 1 Annotations Catalogs SMILES SDF Mol2 Flexibase