ZINC 12

User Information

Not Authenticated — sign in

Active cart: Temporary Cart (0 items)

Navigation

About
- ZINC
- BCIRC
- Irwin Lab
- Shoichet Lab
- UCSF
- Acknowledgements
- Facts
- Usage
Search
- By:
- Text
- Structure
- Properties
- Catalogs
- ZINC
- Targets
- Rings
- Combination
Subsets
- By:
- Catalog
- Property
- Target
- Ring
- Cart
Help
- Introduction
- FAQ
- Scripting/API
- Quick Search
- Problems
- Filtering
- History
Social
- ZINC Fans
- Decoy Club
- DOCK Fans
- Facebook
- Twitter
- Blog
- Linkedin
Quick Search ZINC ID or SMILES

Names
Compounds (461)
Reactome (2)
Related By:
Pathway (14)
Organism (1)
Gene (0)
Org. Clust. (0)
ChEMBL (47)
Rings (20)

Vasopressin V1a Receptor, Human (461 Compounds)

Swissprot:: V1AR_HUMAN
Stitch:: V1AR_HUMAN
UniProt:: P37288
ChEMBL:: CHEMBL1889
Reactome:: REACT_18283; REACT_17041
PDB:: 1YTV (DOCK); AVPR1A

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	461	11	5	5
Binding ≤ 1μM	384	7	3	5
Functional ≤ 10μM	236	9	1	2

Reactome ID	Description	Species
REACT_18283	G alpha (q) signalling events	Homo sapiens
REACT_17041	Vasopressin-like receptors	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	1
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) Receptor, Human	4
ADA1A_HUMAN	P35348	CHEMBL229	Alpha-1a Adrenergic Receptor, Human	2
ADA1B_HUMAN	P35368	CHEMBL232	Alpha-1b Adrenergic Receptor, Human	2
ADA1D_HUMAN	P25100	CHEMBL223	Alpha-1d Adrenergic Receptor, Human	2
GHSR_HUMAN	Q92847	CHEMBL4616	Ghrelin Receptor, Human	1
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	2
NK1R_HUMAN	P25103	CHEMBL249	Neurokinin 1 Receptor, Human	1
NK2R_HUMAN	P21452	CHEMBL2327	Neurokinin 2 Receptor, Human	2
OXYR_HUMAN	P30559	CHEMBL2049	Oxytocin Receptor, Human	180
V1BR_HUMAN	P47901	CHEMBL1921	Vasopressin V1b Receptor, Human	112

Vasopressin-like receptors

Uniprot	Swissprot	Chembl	Description	Number Shared
OXYR_HUMAN	P30559	CHEMBL2049	Oxytocin Receptor, Human	180
V1BR_HUMAN	P47901	CHEMBL1921	Vasopressin V1b Receptor, Human	112
V2R_HUMAN	P30518	CHEMBL1790	Vasopressin V2 Receptor, Human	298

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
V1AR_RAT	P30560	CHEMBL2868	Vasopressin V1a Receptor, Rat	457	11	3	1

Clustered By Gene (0)

Uniprot	Swissprot	Chembl	Description	Number Shared
V2R_HUMAN	P30518	CHEMBL1790	Vasopressin V2 Receptor, Human	298
OXYR_HUMAN	P30559	CHEMBL2049	Oxytocin Receptor, Human	180
V1BR_HUMAN	P47901	CHEMBL1921	Vasopressin V1b Receptor, Human	112
V1BR_RAT	P48974	CHEMBL2659	Vasopressin V1b Receptor, Rat	74
V1AR_RAT	P30560	CHEMBL2868	Vasopressin V1a Receptor, Rat	60
V2R_RAT	Q00788	CHEMBL3766	Vasopressin V2 Receptor, Rat	59
OXYR_RAT	P70536	CHEMBL3996	Oxytocin Receptor, Rat	22
OPRK_HUMAN	P41145	CHEMBL237	Kappa Opioid Receptor, Human	7
OPRM_HUMAN	P35372	CHEMBL233	Mu Opioid Receptor, Human	6
5HT2C_HUMAN	P28335	CHEMBL225	Serotonin 2c (5-HT2c) Receptor, Human	4
AA3R_HUMAN	P33765	CHEMBL256	Adenosine A3 Receptor, Human	3
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	3
5HT1A_HUMAN	P08908	CHEMBL214	Serotonin 1a (5-HT1a) Receptor, Human	2
5HT1B_HUMAN	P28222	CHEMBL1898	Serotonin 1b (5-HT1b) Receptor, Human	2
ADA1A_HUMAN	P35348	CHEMBL229	Alpha-1a Adrenergic Receptor, Human	2
ADA1B_HUMAN	P35368	CHEMBL232	Alpha-1b Adrenergic Receptor, Human	2
ADA1D_HUMAN	P25100	CHEMBL223	Alpha-1d Adrenergic Receptor, Human	2
DRD1_HUMAN	P21728	CHEMBL2056	Dopamine D1 Receptor, Human	2
DRD5_HUMAN	P21918	CHEMBL1850	Dopamine D5 Receptor, Human	2
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	2
HRH2_HUMAN	P25021	CHEMBL1941	Histamine H2 Receptor, Human	2
NK2R_HUMAN	P21452	CHEMBL2327	Neurokinin 2 Receptor, Human	2
OPRD_HUMAN	P41143	CHEMBL236	Delta Opioid Receptor, Human	2
SC6A2_HUMAN	P23975	CHEMBL222	Norepinephrine Transporter, Human	2
5HT2A_HUMAN	P28223	CHEMBL224	Serotonin 2a (5-HT2a) Receptor, Human	1
5HT6R_HUMAN	P50406	CHEMBL3371	Serotonin 6 (5-HT6) Receptor, Human	1
5HT7R_HUMAN	P34969	CHEMBL3155	Serotonin 7 (5-HT7) Receptor, Human	1
AA1R_HUMAN	P30542	CHEMBL226	Adenosine A1 Receptor, Human	1
CAC1C_HUMAN	Q13936	CHEMBL1940	Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Human	1
CAC1D_HUMAN	Q01668	CHEMBL4138	Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Human	1
CAC1F_HUMAN	O60840	CHEMBL5593	Voltage-gated L-type Calcium Channel Alpha-1F Subunit, Human	1
CAC1S_HUMAN	Q13698	CHEMBL3805	Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Human	1
CCR1_HUMAN	P32246	CHEMBL2413	C-C Chemokine Receptor Type 1, Human	1
CNR1_HUMAN	P21554	CHEMBL218	Cannabinoid CB1 Receptor, Human	1
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	1
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 Receptor, Human	1
GHSR_HUMAN	Q92847	CHEMBL4616	Ghrelin Receptor, Human	1
HRH3_HUMAN	Q9Y5N1	CHEMBL264	Histamine H3 Receptor, Human	1
HRH3_RAT	Q9QYN8	CHEMBL4124	Histamine H3 Receptor, Rat	1
HRH4_HUMAN	Q9H3N8	CHEMBL3759	Histamine H4 Receptor, Human	1
HRH4_RAT	Q91ZY1	CHEMBL4468	Histamine H4 Receptor, Rat	1
MTR1A_HUMAN	P48039	CHEMBL1945	Melatonin Receptor 1A, Human	1
NK1R_HUMAN	P25103	CHEMBL249	Neurokinin 1 Receptor, Human	1
SC6A3_HUMAN	Q01959	CHEMBL238	Dopamine Transporter, Human	1
SC6A5_RAT	P58295	CHEMBL3195	Glycine Transporter 2, Rat	1
SC6A9_RAT	P28572	CHEMBL4556	Glycine Transporter 1, Rat	1
TSPOB_HUMAN	B1AH88	CHEMBL5139	Peripheral-type Benzodiazepine Receptor, Human	1