UCSF

Vasopressin V2 Receptor, Human (396 Compounds)

Swissprot:
V2R_HUMAN
Stitch:
V2R_HUMAN
UniProt:
P30518
ChEMBL:
CHEMBL1790
Reactome:
REACT_19327
REACT_24023
REACT_17041
PDB:
AVPR2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 396 8 6 7
Binding ≤ 1μM 361 6 6 7
Functional ≤ 10μM 136 1 2 2

Reactome Network (3)

Reactome ID Description Species
REACT_19327 G alpha (s) signalling events Homo sapiens
REACT_24023 Vasopressin regulates renal water homeostasis via Aquaporins Homo sapiens
REACT_17041 Vasopressin-like receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
OXYR_HUMAN P30559 CHEMBL2049 Oxytocin Receptor, Human 52
V1AR_HUMAN P37288 CHEMBL1889 Vasopressin V1a Receptor, Human 298
V1BR_HUMAN P47901 CHEMBL1921 Vasopressin V1b Receptor, Human 37
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
V2R_BOVIN P48044 CHEMBL2344 Vasopressin V2 Receptor, Bovin 0 0 0 0
V2R_PIG P32307 CHEMBL3944 Vasopressin V2 Receptor, Pig 0 0 0 0
V2R_RAT Q00788 CHEMBL3766 Vasopressin V2 Receptor, Rat 393 10 3 2

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
V1AR_HUMAN P37288 CHEMBL1889 Vasopressin V1a Receptor, Human 298
V2R_RAT Q00788 CHEMBL3766 Vasopressin V2 Receptor, Rat 63
OXYR_HUMAN P30559 CHEMBL2049 Oxytocin Receptor, Human 52
V1AR_RAT P30560 CHEMBL2868 Vasopressin V1a Receptor, Rat 52
V1BR_HUMAN P47901 CHEMBL1921 Vasopressin V1b Receptor, Human 35
V1BR_RAT P48974 CHEMBL2659 Vasopressin V1b Receptor, Rat 30
OXYR_RAT P70536 CHEMBL3996 Oxytocin Receptor, Rat 7
SC6A5_RAT P58295 CHEMBL3195 Glycine Transporter 2, Rat 1
SC6A9_RAT P28572 CHEMBL4556 Glycine Transporter 1, Rat 1

Most Common Rings