ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (144)
Reactome (0)
Related By:
Pathway (0)
Organism (5)
Gene (0)
Org. Clust. (11)
ChEMBL (36)
Rings (8)

Acetylcholinesterase, Torca (144 Compounds)

Swissprot:: ACES_TORCA
Stitch:: ACES_TORCA
UniProt:: P04058
ChEMBL:: CHEMBL4780
PDB:: 1ACJ (DOCK); 1ACL (DOCK); 1AMN (DOCK); 1AX9 (DOCK); 1CFJ (DOCK); 1DX6 (DOCK); 1E3Q (DOCK); 1E66 (DOCK); 1EA5 (DOCK); 1EEA (DOCK); 1EVE (DOCK); 1FSS (DOCK); 1GPK (DOCK); 1GPN (DOCK); 1GQR (DOCK); 1GQS (DOCK); 1H22 (DOCK); 1H23 (DOCK); 1HBJ (DOCK); 1JGA (DOCK); 1JGB (DOCK); 1JJB (DOCK); 1OCE (DOCK); 1ODC (DOCK); 1QID (DOCK); 1QIE (DOCK); 1QIF (DOCK); 1QIG (DOCK); 1QIH (DOCK); 1QII (DOCK); 1QIJ (DOCK); 1QIK (DOCK); 1QIM (DOCK); 1QTI (DOCK); 1SOM (DOCK); 1U65 (DOCK); 1UT6 (DOCK); 1VOT (DOCK); 1VXO (DOCK); 1VXR (DOCK); 1W4L (DOCK); 1W6R (DOCK); 1W75 (DOCK); 1W76 (DOCK); 1ZGB (DOCK); 1ZGC (DOCK); 2ACE (DOCK); 2ACK (DOCK); 2BAG (DOCK); 2C4H (DOCK); 2C58 (DOCK); 2C5F (DOCK); 2C5G (DOCK); 2CEK (DOCK); 2CKM (DOCK); 2CMF (DOCK); 2DFP (DOCK); 2J3D (DOCK); 2J3Q (DOCK); 2J4F (DOCK); 2V96 (DOCK); 2V97 (DOCK); 2V98 (DOCK); 2VA9 (DOCK); 2VJA (DOCK); 2VJB (DOCK); 2VJC (DOCK); 2VJD (DOCK); 2VQ6 (DOCK); 2VT6 (DOCK); 2VT7 (DOCK); 2W6C (DOCK); 2W9I (DOCK); 2WFZ (DOCK); 2WG0 (DOCK); 2WG1 (DOCK); 2WG2 (DOCK); 2XI4 (DOCK); 3ACE (DOCK); 3GEL (DOCK); 3I6M (DOCK); 3I6Z (DOCK); 3M3D (DOCK); 4ACE (DOCK)

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	144	38	13	18
Binding ≤ 1μM	111	26	13	17

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
ACES_BOVIN	P23795	CHEMBL4768	Acetylcholinesterase, Bovin	332	18	13	14
ACES_ELEEL	O42275	CHEMBL4078	Acetylcholinesterase, Eleel	827	43	30	14
ACES_HUMAN	P22303	CHEMBL220	Acetylcholinesterase, Human	1,893	166	81	42
ACES_MOUSE	P21836	CHEMBL3198	Acetylcholinesterase, Mouse	174	27	11	14
ACES_RAT	P37136	CHEMBL3199	Acetylcholinesterase, Rat	712	37	13	17

Clustered By Gene (0)

Clustered By Organism (11)

Code	Description	Substances	Purchasable	Natural	In Man
ACES-1-E	Acetylcholinesterase (cluster #1 Of 12), Eukaryotic	1,833	54	43	24
ACES-10-E	Acetylcholinesterase (cluster #10 Of 12), Eukaryotic	750	87	33	18
ACES-11-E	Acetylcholinesterase (cluster #11 Of 12), Eukaryotic	0	0	0	0
ACES-12-E	Acetylcholinesterase (cluster #12 Of 12), Eukaryotic	4	3	2	0
ACES-2-E	Acetylcholinesterase (cluster #2 Of 12), Eukaryotic	427	36	9	6
ACES-3-E	Acetylcholinesterase (cluster #3 Of 12), Eukaryotic	24	1	4	0
ACES-4-E	Acetylcholinesterase (cluster #4 Of 12), Eukaryotic	9	3	5	1
ACES-5-E	Acetylcholinesterase (cluster #5 Of 12), Eukaryotic	336	29	9	8
ACES-6-E	Acetylcholinesterase (cluster #6 Of 12), Eukaryotic	62	1	1	1
ACES-7-E	Acetylcholinesterase (cluster #7 Of 12), Eukaryotic	1	1	0	0
ACES-8-E	Acetylcholinesterase (cluster #8 Of 12), Eukaryotic	36	5	3	1
ACES-9-E	Acetylcholinesterase (cluster #9 Of 12), Eukaryotic	18	10	3	4

Uniprot	Swissprot	Chembl	Description	Number Shared
ACES_HUMAN	P22303	CHEMBL220	Acetylcholinesterase, Human	74
ACES_ELEEL	O42275	CHEMBL4078	Acetylcholinesterase, Eleel	36
CHLE_HUMAN	P06276	CHEMBL1914	Butyrylcholinesterase, Human	26
ACES_BOVIN	P23795	CHEMBL4768	Acetylcholinesterase, Bovin	18
ACES_RAT	P37136	CHEMBL3199	Acetylcholinesterase, Rat	8
ACES_MOUSE	P21836	CHEMBL3198	Acetylcholinesterase, Mouse	7
ACM2_PIG	P06199	CHEMBL4781	Muscarinic Acetylcholine Receptor M2, Pig	5
CHLE_HORSE	P81908	CHEMBL5763	Cholinesterase, Horse	5
Q9JKC1_RAT	Q9JKC1	CHEMBL3403	Butyrylcholinesterase, Rat	5
Q9N1N9_HORSE	Q9N1N9	CHEMBL5077	Butyrylcholinesterase, Horse	4
CHLE_MOUSE	Q03311	CHEMBL2528	Butyrylcholinesterase, Mouse	3
CLAT_RAT	P32738	CHEMBL3945	Choline Acetylase, Rat	3
KCNH2_HUMAN	Q12809	CHEMBL240	HERG, Human	3
HRH3_HUMAN	Q9Y5N1	CHEMBL264	Histamine H3 Receptor, Human	2
5HT2A_RAT	P14842	CHEMBL322	Serotonin 2a (5-HT2a) Receptor, Rat	1
5HT2B_RAT	P30994	CHEMBL323	Serotonin 2b (5-HT2b) Receptor, Rat	1
5HT2C_RAT	P08909	CHEMBL324	Serotonin 2c (5-HT2c) Receptor, Rat	1
5HT4R_HUMAN	Q13639	CHEMBL1875	Serotonin 4 (5-HT4) Receptor, Human	1
5HT4R_RAT	Q62758	CHEMBL4317	Serotonin 4 (5-HT4) Receptor, Rat	1
ACHE_HUMAN	Q04844	CHEMBL2484	Acetylcholine Receptor Protein Epsilon Chain, Human	1
ACM1_MOUSE	P12657	CHEMBL3733	Muscarinic Acetylcholine Receptor M1, Mouse	1
ACM2_MOUSE	Q9ERZ4	CHEMBL3197	Muscarinic Acetylcholine Receptor M2, Mouse	1
ACM2_RAT	P10980	CHEMBL309	Muscarinic Acetylcholine Receptor M2, Rat	1
ADA2A_RAT	P22909	CHEMBL327	Alpha-2a Adrenergic Receptor, Rat	1
ADA2B_RAT	P19328	CHEMBL266	Alpha-2b Adrenergic Receptor, Rat	1
ADA2C_RAT	P22086	CHEMBL314	Alpha-2c Adrenergic Receptor, Rat	1
DRD1_BOVIN	Q95136	CHEMBL2967	Dopamine D1 Receptor, Bovin	1
DRD2_HUMAN	P14416	CHEMBL217	Dopamine D2 Receptor, Human	1
DRD2_RAT	P61169	CHEMBL339	Dopamine D2 Receptor, Rat	1
DRD3_HUMAN	P35462	CHEMBL234	Dopamine D3 Receptor, Human	1
DRD4_HUMAN	P21917	CHEMBL219	Dopamine D4 Receptor, Human	1
HNMT_RAT	Q01984	CHEMBL3241	Histamine N-methyltransferase, Rat	1
SC5A7_MOUSE	Q8BGY9	CHEMBL3013	Choline Transporter, Mouse	1
Z104298	Z104298	CHEMBL1907604	Glutamate NMDA Receptor; GRIN1/GRIN2A	1
Z104302	Z104302	CHEMBL1907608	Glutamate NMDA Receptor	1
Z104303	Z104303	CHEMBL1907609	Muscarinic Acetylcholine Receptor	1