LXR-alpha, Human (485 Compounds)

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	485	14	11	3
Binding ≤ 1μM	425	11	8	2
Functional ≤ 10μM	209	2	3	1

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
NR1H2_HUMAN	P55055	CHEMBL4093	LXR-beta, Human	442	4	4	2
NR1H4_HUMAN	Q96RI1	CHEMBL2047	Bile Acid Receptor FXR, Human	372	7	7	3

Code	Description	Substances	Purchasable	Natural	In Man
NR1H3-1-E	LXR-alpha (cluster #1 Of 2), Eukaryotic	453	8	3	2
NR1H3-2-E	LXR-alpha (cluster #2 Of 2), Eukaryotic	36	7	8	1

Uniprot	Swissprot	Chembl	Description	Number Shared
NR1H2_HUMAN	P55055	CHEMBL4093	LXR-beta, Human	471
Z80548	Z80548	CHEMBL614245	THP-1 (Acute Monocytic Leukemia Cells)	29
PPARD_HUMAN	Q03181	CHEMBL3979	Peroxisome Proliferator-activated Receptor Delta, Human	21
PPARA_HUMAN	Q07869	CHEMBL239	Peroxisome Proliferator-activated Receptor Alpha, Human	19
PPARG_HUMAN	P37231	CHEMBL235	Peroxisome Proliferator-activated Receptor Gamma, Human	17
Z81020	Z81020	CHEMBL395	HepG2 (Hepatoblastoma Cells)	13
Z81244	Z81244	CHEMBL614123	J774 (Macrophage Cells)	5
NR1I2_HUMAN	O75469	CHEMBL3401	Pregnane X Receptor, Human	4
Z50594	Z50594	CHEMBL375	Mus Musculus	3
Z80178	Z80178	CHEMBL614040	J774.A1 (Macrophage Cells)	3
GCR_HUMAN	P04150	CHEMBL2034	Glucocorticoid Receptor, Human	2
Z80169	Z80169	CHEMBL614039	Huh-7 (Hepatocellular Carcinoma)	2
ANDR_HUMAN	P10275	CHEMBL1871	Androgen Receptor, Human	1
SRBP2_HUMAN	Q12772	CHEMBL1795166	Sterol Regulatory Element-binding Protein 2, Human	1
Z80418	Z80418	CHEMBL612557	RAW264.7 (Monocytic-macrophage Leukemia Cells)	1