UCSF

Sodium/glucose Cotransporter 2, Human (576 Compounds)

Swissprot:
SC5A2_HUMAN
Stitch:
SC5A2_HUMAN
UniProt:
P31639
ChEMBL:
CHEMBL3884
Reactome:
REACT_9441
REACT_19188
REACT_19165
PDB:
SLC5A2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 576 14 5 1
Binding ≤ 1μM 502 2 2 1
Functional ≤ 10μM 20 0 0 0

Reactome Network (3)

Reactome ID Description Species
REACT_9441 Hexose transport Homo sapiens
REACT_19188 Inositol transporters Homo sapiens
REACT_19165 Na+-dependent glucose transporters Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
SC5A1_HUMAN P13866 CHEMBL4979 Sodium/glucose Cotransporter 1, Human 117
SC5A4_HUMAN Q9NY91 CHEMBL1770047 Low Affinity Sodium-glucose Cotransporter, Human 4

Inositol transporters

Uniprot Swissprot Chembl Description Number Shared
SC5A1_HUMAN P13866 CHEMBL4979 Sodium/glucose Cotransporter 1, Human 117
SC5A4_HUMAN Q9NY91 CHEMBL1770047 Low Affinity Sodium-glucose Cotransporter, Human 4
SC5AB_HUMAN Q8WWX8 CHEMBL1744524 Sodium/myo-inositol Cotransporter 2, Human 2

Na+-dependent glucose transporters

Uniprot Swissprot Chembl Description Number Shared
SC5A1_HUMAN P13866 CHEMBL4979 Sodium/glucose Cotransporter 1, Human 117
SC5A4_HUMAN Q9NY91 CHEMBL1770047 Low Affinity Sodium-glucose Cotransporter, Human 4
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SC5A2_MOUSE Q923I7 CHEMBL1075302 Sodium/glucose Cotransporter 2, Mouse 44 1 0 0
SC5A2_RAT P53792 CHEMBL4316 Sodium/glucose Cotransporter 2, Rat 5 3 1 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
SC5A1_HUMAN P13866 CHEMBL4979 Sodium/glucose Cotransporter 1, Human 153 5 4 1
SC5A4_HUMAN Q9NY91 CHEMBL1770047 Low Affinity Sodium-glucose Cotransporter, Human 30 3 2 1
SC5A7_HUMAN Q9GZV3 CHEMBL4507 High-affinity Choline Transporter, Human 2 1 0 0
SC5AB_HUMAN Q8WWX8 CHEMBL1744524 Sodium/myo-inositol Cotransporter 2, Human 2 1 1 1

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
SC5A1_HUMAN P13866 CHEMBL4979 Sodium/glucose Cotransporter 1, Human 117
SC5A2_MOUSE Q923I7 CHEMBL1075302 Sodium/glucose Cotransporter 2, Mouse 42
SC5A2_RAT P53792 CHEMBL4316 Sodium/glucose Cotransporter 2, Rat 4
SC5A4_HUMAN Q9NY91 CHEMBL1770047 Low Affinity Sodium-glucose Cotransporter, Human 4
BACE1_HUMAN P56817 CHEMBL4822 Beta-secretase 1, Human 3
ESR1_HUMAN P03372 CHEMBL206 Estrogen Receptor Alpha, Human 2
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 2
SC5AB_HUMAN Q8WWX8 CHEMBL1744524 Sodium/myo-inositol Cotransporter 2, Human 2
Q9QXI6_MOUSE Q9QXI6 CHEMBL1744523 SGLT1 Protein, Mouse 1
SC5A1_RAT P53790 CHEMBL5374 Sodium/glucose Cotransporter 1, Rat 1

Most Common Rings