ZINC 12

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Quick Search ZINC ID or SMILES

Names
Compounds (371)
Reactome (1)
Related By:
Pathway (1)
Organism (3)
Gene (1)
Org. Clust. (1)
ChEMBL (28)
Rings (9)

Fructose-1,6-bisphosphatase, Human (371 Compounds)

Swissprot:: F16P1_HUMAN
Stitch:: F16P1_HUMAN
UniProt:: P09467
ChEMBL:: CHEMBL3975
Reactome:: REACT_1520
PDB:: 1FTA (DOCK); 2FHY (DOCK); 2FIE (DOCK); 2FIX (DOCK); 2JJK (DOCK); 2VT5 (DOCK); 2WBB (DOCK); 2WBD (DOCK); 2Y5K (DOCK); 2Y5L (DOCK); 3A29 (DOCK); 3KBZ (DOCK); 3KC0 (DOCK); 3KC1 (DOCK); FBP1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	371	8	1	7
Binding ≤ 1μM	241	6	1	5

Reactome ID	Description	Species
REACT_1520	Gluconeogenesis	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
F16P2_HUMAN	O00757	CHEMBL3877	Fructose-1,6-bisphosphatase 2, Human	71

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
F16P1_MOUSE	Q9QXD6	CHEMBL5360	Fructose-1,6-bisphosphatase 1, Mouse	38	0	0	0
F16P1_PIG	P00636	CHEMBL2263	Fructose-1,6-bisphosphatase, Pig	14	4	1	3
F16P1_RAT	P19112	CHEMBL4391	Fructose-1,6-bisphosphatase, Rat	37	0	0	1

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
F16P2_HUMAN	O00757	CHEMBL3877	Fructose-1,6-bisphosphatase 2, Human	71	1	0	2

Clustered By Gene (0)

Clustered By Organism (1)

Code	Description	Substances	Purchasable	Natural	In Man
F16P1-1-E	Fructose-1,6-bisphosphatase 1 (cluster #1 Of 2), Eukaryotic	259	7	1	5
F16P1-2-E	Fructose-1,6-bisphosphatase 1 (cluster #2 Of 2), Eukaryotic	118	2	0	3

Uniprot	Swissprot	Chembl	Description	Number Shared
F16P2_HUMAN	O00757	CHEMBL3877	Fructose-1,6-bisphosphatase 2, Human	71
F16P1_RAT	P19112	CHEMBL4391	Fructose-1,6-bisphosphatase, Rat	37
F16P1_MOUSE	Q9QXD6	CHEMBL5360	Fructose-1,6-bisphosphatase 1, Mouse	34
EGFR_HUMAN	P00533	CHEMBL203	Epidermal Growth Factor Receptor ErbB1, Human	23
F16P1_PIG	P00636	CHEMBL2263	Fructose-1,6-bisphosphatase, Pig	12
MKNK1_HUMAN	Q9BUB5	CHEMBL4718	MAP Kinase-interacting Serine/threonine-protein Kinase MNK1, Human	3
SRC_HUMAN	P12931	CHEMBL267	Tyrosine-protein Kinase SRC, Human	3
ABL1_HUMAN	P00519	CHEMBL1862	Tyrosine-protein Kinase ABL, Human	2
ERBB2_HUMAN	P04626	CHEMBL1824	Receptor Protein-tyrosine Kinase ErbB-2, Human	2
LCK_HUMAN	P06239	CHEMBL258	Tyrosine-protein Kinase LCK, Human	2
MK14_HUMAN	Q16539	CHEMBL260	MAP Kinase P38 Alpha, Human	2
NMDZ1_RAT	P35439	CHEMBL330	Glutamate (NMDA) Receptor Subunit Zeta 1, Rat	2
VGFR2_HUMAN	P35968	CHEMBL279	Vascular Endothelial Growth Factor Receptor 2, Human	2
Z104302	Z104302	CHEMBL1907608	Glutamate NMDA Receptor	2
ABL2_HUMAN	P42684	CHEMBL4014	Tyrosine-protein Kinase ABL2, Human	1
AURKA_HUMAN	O14965	CHEMBL4722	Serine/threonine-protein Kinase Aurora-A, Human	1
AURKB_HUMAN	Q96GD4	CHEMBL2185	Serine/threonine-protein Kinase Aurora-B, Human	1
EPHB2_HUMAN	P29323	CHEMBL3290	Ephrin Type-B Receptor 2, Human	1
EPHB4_HUMAN	P54760	CHEMBL5147	Ephrin Type-B Receptor 4, Human	1
INSR_HUMAN	P06213	CHEMBL1981	Insulin Receptor, Human	1
MK11_HUMAN	Q15759	CHEMBL3961	MAP Kinase P38 Beta, Human	1
MK12_HUMAN	P53778	CHEMBL4674	MAP Kinase P38 Gamma, Human	1
MK13_HUMAN	O15264	CHEMBL2939	MAP Kinase P38 Delta, Human	1
NMDE3_RAT	Q00961	CHEMBL401	Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat	1
PGFRB_HUMAN	P09619	CHEMBL1913	Platelet-derived Growth Factor Receptor Beta, Human	1
Q72874_9HIV1	Q72874	CHEMBL243	Human Immunodeficiency Virus Type 1 Protease, 9hiv1	1
TIE2_HUMAN	Q02763	CHEMBL4128	Tyrosine-protein Kinase TIE-2, Human	1
VGFR3_HUMAN	P35916	CHEMBL1955	Vascular Endothelial Growth Factor Receptor 3, Human	1