| Annotation Type | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|
| Binding ≤ 10μM | 1,114 | 14 | 0 | 0 |
| Binding ≤ 1μM | 1,047 | 12 | 0 | 0 |
| Functional ≤ 10μM | 176 | 13 | 0 | 0 |
| Reactome ID | Description | Species |
|---|---|---|
| REACT_19231 | G alpha (i) signalling events | Homo sapiens |
| REACT_14819 | Peptide ligand-binding receptors | Homo sapiens |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| 5HT1A_HUMAN | P08908 | CHEMBL214 | Serotonin 1a (5-HT1a) Receptor, Human | 2 |
| ADA2A_HUMAN | P08913 | CHEMBL1867 | Alpha-2a Adrenergic Receptor, Human | 19 |
| ADA2C_HUMAN | P18825 | CHEMBL1916 | Alpha-2c Adrenergic Receptor, Human | 2 |
| DRD2_HUMAN | P14416 | CHEMBL217 | Dopamine D2 Receptor, Human | 2 |
| MCHR1_HUMAN | Q99705 | CHEMBL344 | Melanin-concentrating Hormone Receptor 1, Human | 18 |
| NPY1R_HUMAN | P25929 | CHEMBL4777 | Neuropeptide Y Receptor Type 1, Human | 38 |
| NPY2R_HUMAN | P49146 | CHEMBL4018 | Neuropeptide Y Receptor Type 2, Human | 6 |
| NPY4R_HUMAN | P50391 | CHEMBL4877 | Neuropeptide Y Receptor Type 4, Human | 1 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| MCHR1_HUMAN | Q99705 | CHEMBL344 | Melanin-concentrating Hormone Receptor 1, Human | 18 |
| NPY1R_HUMAN | P25929 | CHEMBL4777 | Neuropeptide Y Receptor Type 1, Human | 38 |
| NPY2R_HUMAN | P49146 | CHEMBL4018 | Neuropeptide Y Receptor Type 2, Human | 6 |
| NPY4R_HUMAN | P50391 | CHEMBL4877 | Neuropeptide Y Receptor Type 4, Human | 1 |
| UniProt | Swissprot | ChEMBL | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|---|---|
| NPY5R_MOUSE | O70342 | CHEMBL3802 | Neuropeptide Y Receptor Type 5, Mouse | 26 | 0 | 0 | 0 |
| NPY5R_RAT | Q63634 | CHEMBL2548 | Neuropeptide Y Receptor Type 5, Rat | 55 | 3 | 0 | 0 |
| Code | Description | Substances | Purchasable | Natural | In Man |
|---|---|---|---|---|---|
| NPY5R-1-E | Neuropeptide Y Receptor Type 5 (cluster #1 Of 2), Eukaryotic | 632 | 12 | 0 | 0 |
| NPY5R-2-E | Neuropeptide Y Receptor Type 5 (cluster #2 Of 2), Eukaryotic | 560 | 5 | 0 | 0 |
| Uniprot | Swissprot | Chembl | Description | Number Shared |
|---|---|---|---|---|
| NPY1R_HUMAN | P25929 | CHEMBL4777 | Neuropeptide Y Receptor Type 1, Human | 37 |
| ADA1A_HUMAN | P35348 | CHEMBL229 | Alpha-1a Adrenergic Receptor, Human | 19 |
| ADA2A_HUMAN | P08913 | CHEMBL1867 | Alpha-2a Adrenergic Receptor, Human | 19 |
| MCHR1_HUMAN | Q99705 | CHEMBL344 | Melanin-concentrating Hormone Receptor 1, Human | 18 |
| NPY5R_RAT | Q63634 | CHEMBL2548 | Neuropeptide Y Receptor Type 5, Rat | 18 |
| KCNH2_HUMAN | Q12809 | CHEMBL240 | HERG, Human | 12 |
| NPY2R_HUMAN | P49146 | CHEMBL4018 | Neuropeptide Y Receptor Type 2, Human | 6 |
| ADA2C_HUMAN | P18825 | CHEMBL1916 | Alpha-2c Adrenergic Receptor, Human | 2 |
| DRD2_HUMAN | P14416 | CHEMBL217 | Dopamine D2 Receptor, Human | 2 |
| O70424_RAT | O70424 | CHEMBL1293206 | Neuropeptide Y-Y2 Receptor, Rat | 2 |
| 5HT1A_HUMAN | P08908 | CHEMBL214 | Serotonin 1a (5-HT1a) Receptor, Human | 1 |
| 5HT2B_HUMAN | P41595 | CHEMBL1833 | Serotonin 2b (5-HT2b) Receptor, Human | 1 |
| ADA1A_RAT | P43140 | CHEMBL319 | Alpha-1a Adrenergic Receptor, Rat | 1 |
| ADA1B_RAT | P15823 | CHEMBL315 | Alpha-1b Adrenergic Receptor, Rat | 1 |
| ADA1D_RAT | P23944 | CHEMBL326 | Alpha-1d Adrenergic Receptor, Rat | 1 |
| ADA2A_RAT | P22909 | CHEMBL327 | Alpha-2a Adrenergic Receptor, Rat | 1 |
| ADA2B_RAT | P19328 | CHEMBL266 | Alpha-2b Adrenergic Receptor, Rat | 1 |
| ADA2C_RAT | P22086 | CHEMBL314 | Alpha-2c Adrenergic Receptor, Rat | 1 |
| HRH1_HUMAN | P35367 | CHEMBL231 | Histamine H1 Receptor, Human | 1 |
| NPY4R_HUMAN | P50391 | CHEMBL4877 | Neuropeptide Y Receptor Type 4, Human | 1 |
| NPY5R_MOUSE | O70342 | CHEMBL3802 | Neuropeptide Y Receptor Type 5, Mouse | 1 |
| SC6A4_HUMAN | P31645 | CHEMBL228 | Serotonin Transporter, Human | 1 |
| SCN2A_HUMAN | Q99250 | CHEMBL4187 | Sodium Channel Protein Type II Alpha Subunit, Human | 1 |
| Z50597 | Z50597 | CHEMBL376 | Rattus Norvegicus | 1 |
