UCSF

Histamine H2 Receptor, Guinea Pig (16 Compounds)

Swissprot:
HRH2_CAVPO
Stitch:
HRH2_CAVPO
UniProt:
P47747
ChEMBL:
CHEMBL2882
PDB:
HRH2

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 16 4 4 4
Binding ≤ 1μM 15 3 3 3
Functional ≤ 10μM 2 0 0 0

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
HRH2_HUMAN P25021 CHEMBL1941 Histamine H2 Receptor, Human 144 13 10 5
HRH2_RAT P25102 CHEMBL4654 Histamine H2 Receptor, Rat 23 3 3 4
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
HRH1_CAVPO P31389 CHEMBL3943 Histamine H1 Receptor, Guinea Pig 93 7 6 6
HRH3_CAVPO Q9JI35 CHEMBL5076 Histamine H3 Receptor, Guinea Pig 125 5 8 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
HRH2-1-E Histamine H2 Receptor (cluster #1 Of 3), Eukaryotic 139 8 6 5
HRH2-2-E Histamine H2 Receptor (cluster #2 Of 3), Eukaryotic 32 6 7 4
HRH2-3-E Histamine H2 Receptor (cluster #3 Of 3), Eukaryotic 3 3 1 1
Uniprot Swissprot Chembl Description Number Shared
HRH2_HUMAN P25021 CHEMBL1941 Histamine H2 Receptor, Human 10
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 8
HRH3_HUMAN Q9Y5N1 CHEMBL264 Histamine H3 Receptor, Human 5
HRH1_CAVPO P31389 CHEMBL3943 Histamine H1 Receptor, Guinea Pig 3
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 2
HRH4_RAT Q91ZY1 CHEMBL4468 Histamine H4 Receptor, Rat 2
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 1
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 1
5HT1B_HUMAN P28222 CHEMBL1898 Serotonin 1b (5-HT1b) Receptor, Human 1
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 1
5HT1D_HUMAN P28221 CHEMBL1983 Serotonin 1d (5-HT1d) Receptor, Human 1
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 1
5HT1E_HUMAN P28566 CHEMBL2182 Serotonin 1e (5-HT1e) Receptor, Human 1
5HT1F_HUMAN P30939 CHEMBL1805 Serotonin 1f (5-HT1f) Receptor, Human 1
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 1
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 1
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 1
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 1
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 1
5HT3A_MOUSE P23979 CHEMBL4972 Serotonin 3a (5-HT3a) Receptor, Mouse 1
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 1
5HT3B_MOUSE Q9JHJ5 CHEMBL3781 Serotonin 3b (5-HT3b) Receptor, Mouse 1
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 1
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 1
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 1
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 1
ACM5_RAT P08911 CHEMBL277 Muscarinic Acetylcholine Receptor M5, Rat 1
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 1
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 1
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 1
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 1
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 1
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 1
ADA2A_BOVIN Q28838 CHEMBL4744 Alpha-2a Adrenergic Receptor, Bovin 1
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 1
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 1
ADA2B_BOVIN O77700 CHEMBL3523 Alpha-2b Adrenergic Receptor, Bovin 1
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 1
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 1
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 1
ADCY1_HUMAN Q08828 CHEMBL2899 Brain Adenylate Cyclase 1, Human 1
ADCY2_HUMAN Q08462 CHEMBL3760 Adenylate Cyclase Type II, Human 1
ADCY8_HUMAN P40145 CHEMBL2960 Adenylate Cyclase Type VIII, Human 1
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 1
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 1
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 1
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 1
HRH2_RAT P25102 CHEMBL4654 Histamine H2 Receptor, Rat 1
HRH3_MOUSE P58406 CHEMBL3263 Histamine H3 Receptor, Mouse 1
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 1
HRH4_MOUSE Q91ZY2 CHEMBL5657 Histamine H4 Receptor, Mouse 1
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 1
SC6A4_RAT P31652 CHEMBL313 Serotonin Transporter, Rat 1
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 1
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 1
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 1
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 1
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1

Most Common Rings