UCSF

Corticotropin Releasing Factor Receptor 1, Rat (621 Compounds)

Swissprot:
CRFR1_RAT
Stitch:
CRFR1_RAT
UniProt:
P35353
ChEMBL:
CHEMBL4649
Reactome:
REACT_262688
REACT_246814
PDB:
Crhr1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 621 4 0 1
Binding ≤ 1μM 592 4 0 1
Functional ≤ 10μM 37 0 0 1

Reactome Network (2)

Reactome ID Description Species
REACT_262688 Class B/2 (Secretin family receptors) Rattus norvegicus
REACT_246814 G alpha (s) signalling events Rattus norvegicus
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CRFR1_HUMAN P34998 CHEMBL1800 Corticotropin Releasing Factor Receptor 1, Human 1,345 9 3 3
CRFR1_MOUSE P35347 CHEMBL2446 Corticotropin Releasing Factor Receptor 1, Mouse 2 0 0 0
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CRFR2_RAT P47866 CHEMBL3581 Corticotropin Releasing Factor Receptor 2, Rat 148 2 0 0

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
CRFR1-1-E Corticotropin Releasing Factor Receptor 1 (cluster #1 Of 3), Eukaryotic 1,972 9 2 2
CRFR1-2-E Corticotropin Releasing Factor Receptor 1 (cluster #2 Of 3), Eukaryotic 1 1 1 1
CRFR1-3-E Corticotropin Releasing Factor Receptor 1 (cluster #3 Of 3), Eukaryotic 0 0 0 0
Uniprot Swissprot Chembl Description Number Shared
CRFR2_RAT P47866 CHEMBL3581 Corticotropin Releasing Factor Receptor 2, Rat 177
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 21
CRFR1_HUMAN P34998 CHEMBL1800 Corticotropin Releasing Factor Receptor 1, Human 18
CRFR2_MOUSE Q60748 CHEMBL2253 Corticotropin Releasing Factor Receptor 2, Mouse 10
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 4
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 4
NPY1R_HUMAN P25929 CHEMBL4777 Neuropeptide Y Receptor Type 1, Human 4
CRFR1_MOUSE P35347 CHEMBL2446 Corticotropin Releasing Factor Receptor 1, Mouse 2
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 1
NK2R_HUMAN P21452 CHEMBL2327 Neurokinin 2 Receptor, Human 1

Most Common Rings