UCSF
Image of 1H-pyrrolo[2,3-b]pyridine

Identity 99% 90% 80% 70% Substructure

1H-pyrrolo[2,3-b]pyridine

PubMed — Wikipedia — Google

Ring Information

Rings Ring Systems Atoms Carbons Nitrogens Oxygens Sulfurs
2 1 9 7 2 0 0

Subset Information

Substances Natural Purchasable Annotated BB In Man Last Updated
View 0 2,239 54 31 1 2012-03-07

Most Common Targets

Name (Uniprot) Swissprot ChEMBL Description Size Browse Download (Annotations)
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 20 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81247 Z81247 CHEMBL399 HeLa (Cervical Adenocarcinoma Cells) 19 Annotations Catalogs SMILES SDF Mol2 Flexibase
CRFR1_RAT P35353 CHEMBL4649 Corticotropin Releasing Factor Receptor 1, Rat 15 Annotations Catalogs SMILES SDF Mol2 Flexibase
CRFR1_RAT P35353 CHEMBL4649 Corticotropin Releasing Factor Receptor 1, Rat 13 Annotations Catalogs SMILES SDF Mol2 Flexibase
RET_HUMAN P07949 CHEMBL2041 Tyrosine-protein Kinase Receptor RET, Human 7 Annotations Catalogs SMILES SDF Mol2 Flexibase
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
MTOR_HUMAN P42345 CHEMBL2842 FK506 Binding Protein 12, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
PK3CA_HUMAN P42336 CHEMBL4005 PI3-kinase P110-alpha Subunit, Human 5 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 4 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKA_HUMAN O14965 CHEMBL4722 Serine/threonine-protein Kinase Aurora-A, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
RET_HUMAN P07949 CHEMBL2041 Tyrosine-protein Kinase Receptor RET, Human 3 Annotations Catalogs SMILES SDF Mol2 Flexibase
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
ABL1_HUMAN P00519 CHEMBL1862 Tyrosine-protein Kinase ABL, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
VGFR2_HUMAN P35968 CHEMBL279 Vascular Endothelial Growth Factor Receptor 2, Human 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80036 Z80036 CHEMBL614524 BaF3 (IL-3-dependent Pro-B-cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81057 Z81057 CHEMBL613979 HUVEC (Umbilical Vein Endothelial Cells) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z81170 Z81170 CHEMBL612518 LNCaP (Prostate Carcinoma) 2 Annotations Catalogs SMILES SDF Mol2 Flexibase
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
AKT1_HUMAN P31749 CHEMBL4282 Serine/threonine-protein Kinase AKT, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
AURKB_HUMAN Q96GD4 CHEMBL2185 Serine/threonine-protein Kinase Aurora-B, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
BCR_HUMAN P11274 CHEMBL5146 Breakpoint Cluster Region Protein, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
BCR_HUMAN P11274 CHEMBL5146 Breakpoint Cluster Region Protein, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2C9_HUMAN P11712 CHEMBL3397 Cytochrome P450 2C9, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CP2D6_HUMAN P10635 CHEMBL289 Cytochrome P450 2D6, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CRFR2_RAT P47866 CHEMBL3581 Corticotropin Releasing Factor Receptor 2, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
CRFR2_RAT P47866 CHEMBL3581 Corticotropin Releasing Factor Receptor 2, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
FAAH1_HUMAN O00519 CHEMBL2243 Anandamide Amidohydrolase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
FAAH1_HUMAN O00519 CHEMBL2243 Anandamide Amidohydrolase, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
FAAH1_RAT P97612 CHEMBL3229 Anandamide Amidohydrolase, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
FAAH1_RAT P97612 CHEMBL3229 Anandamide Amidohydrolase, Rat 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
IGF1R_HUMAN P08069 CHEMBL1957 Insulin-like Growth Factor I Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
INCE_HUMAN Q9NQS7 CHEMBL5177 Inner Centromere Protein, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
INCE_HUMAN Q9NQS7 CHEMBL5177 Inner Centromere Protein, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
LYN_HUMAN P07948 CHEMBL3905 Tyrosine-protein Kinase Lyn, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MET_HUMAN P08581 CHEMBL3717 Hepatocyte Growth Factor Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
MET_HUMAN P08581 CHEMBL3717 Hepatocyte Growth Factor Receptor, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
ROCK1_HUMAN Q13464 CHEMBL3231 Rho-associated Protein Kinase 1, Human 1 Annotations Catalogs SMILES SDF Mol2 Flexibase
Z80682 Z80682 CHEMBL392 A549 (Lung Carcinoma Cells) 1 Annotations Catalogs SMILES SDF Mol2 Flexibase