UCSF

Vanilloid Receptor, Rat (508 Compounds)

Swissprot:
TRPV1_RAT
Stitch:
TRPV1_RAT
UniProt:
O35433
ChEMBL:
CHEMBL5102
Reactome:
REACT_198388
PDB:
2NYJ (DOCK)
2PNN (DOCK)
Trpv1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 508 10 3 2
Binding ≤ 1μM 396 7 2 1
Functional ≤ 10μM 897 20 6 4

Reactome Network (1)

Reactome ID Description Species
REACT_198388 TRP channels Rattus norvegicus
Uniprot Swissprot Chembl Description Number Shared
TRPV2_RAT Q9WUD2 CHEMBL2863 Transient Receptor Potential Cation Channel Subfamily V Member 2, Rat 144
TRPV4_RAT Q9ERZ8 CHEMBL2775 Transient Receptor Potential Cation Channel Subfamily V Member 4, Rat 144
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
TRPV1_HUMAN Q8NER1 CHEMBL4794 Vanilloid Receptor, Human 379 23 3 1

Clustered By Gene (0)

Clustered By Organism (2)

Code Description Substances Purchasable Natural In Man
TRPV1-1-E Vanilloid Receptor (cluster #1 Of 3), Eukaryotic 532 7 2 1
TRPV1-2-E Vanilloid Receptor (cluster #2 Of 3), Eukaryotic 308 19 1 1
TRPV1-3-E Vanilloid Receptor (cluster #3 Of 3), Eukaryotic 7 2 2 0
Uniprot Swissprot Chembl Description Number Shared
TRPV1_HUMAN Q8NER1 CHEMBL4794 Vanilloid Receptor, Human 250
TRPV2_RAT Q9WUD2 CHEMBL2863 Transient Receptor Potential Cation Channel Subfamily V Member 2, Rat 144
TRPV4_RAT Q9ERZ8 CHEMBL2775 Transient Receptor Potential Cation Channel Subfamily V Member 4, Rat 144
Z50512 Z50512 CHEMBL369 Cavia Porcellus 13
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 12
Z80088 Z80088 CHEMBL613853 CHO (Ovarian Cells) 9
NMDE1_RAT Q00959 CHEMBL310 Glutamate [NMDA] Receptor Subunit Epsilon 1, Rat 3
NMDZ1_RAT P35439 CHEMBL330 Glutamate (NMDA) Receptor Subunit Zeta 1, Rat 3
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 2
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 1
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 1
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 1
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 1
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 1
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 1
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 1
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 1
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 1
ADCY2_RAT P26769 CHEMBL2958 Adenylate Cyclase Type II, Rat 1
ADCY3_RAT P21932 CHEMBL4864 Adenylate Cyclase Type III, Rat 1
ADCY4_RAT P26770 CHEMBL2879 Adenylate Cyclase Type IV, Rat 1
ADCY5_RAT Q04400 CHEMBL2880 Adenylate Cyclase Type V, Rat 1
ADCY6_RAT Q03343 CHEMBL2975 Adenylate Cyclase Type VI, Rat 1
ADCY8_RAT P40146 CHEMBL3082 Adenylate Cyclase Type VIII, Rat 1
CALM_HUMAN P62158 CHEMBL6093 Calmodulin, Human 1
CNR1_HUMAN P21554 CHEMBL218 Cannabinoid CB1 Receptor, Human 1
CNR1_MOUSE P47746 CHEMBL3037 Cannabinoid CB1 Receptor, Mouse 1
CNR1_RAT P20272 CHEMBL3571 Cannabinoid CB1 Receptor, Rat 1
CNR2_HUMAN P34972 CHEMBL253 Cannabinoid CB2 Receptor, Human 1
CNR2_MOUSE P47936 CHEMBL5373 Cannabinoid CB2 Receptor, Mouse 1
CNR2_RAT Q9QZN9 CHEMBL2470 Cannabinoid CB2 Receptor, Rat 1
D4A3N4_RAT D4A3N4 CHEMBL2679 Brain Adenylate Cyclase 1, Rat 1
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 1
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 1
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 1
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 1
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 1
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 1
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 1
FAAH1_HUMAN O00519 CHEMBL2243 Anandamide Amidohydrolase, Human 1
FAAH1_RAT P97612 CHEMBL3229 Anandamide Amidohydrolase, Rat 1
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 1
MK03_HUMAN P27361 CHEMBL3385 MAP Kinase ERK1, Human 1
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 1
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 1
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 1
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 1
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 1
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 1
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 1
PDR5_YEAST P33302 CHEMBL1697658 Pleiotropic ABC Efflux Transporter Of Multiple Drugs, Yeast 1
PGH1_HUMAN P23219 CHEMBL221 Cyclooxygenase-1, Human 1
PRIO_HUMAN P04156 CHEMBL4869 Prion Protein, Human 1
Q8CFM9_RAT Q8CFM9 CHEMBL3940 Adenylate Cyclase Type VII, Rat 1
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 1
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 1
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 1
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 1
TRPA1_HUMAN O75762 CHEMBL6007 Transient Receptor Potential Cation Channel Subfamily A Member 1, Human 1
TRPV1_CAVPO Q6R5A3 CHEMBL5132 Vanilloid Receptor 1, Guinea Pig 1
TYTR_TRYCR P28593 CHEMBL5131 Trypanothione Reductase, Trycr 1
Z101682 Z101682 CHEMBL613915 BK Polyomavirus 1
Z102380 Z102380 CHEMBL613680 Ileum 1
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 1
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 1
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 1
Z50636 Z50636 CHEMBL613725 Sindbis Virus 1

Most Common Rings