UCSF

Muscarinic Acetylcholine Receptor M4, Rat (174 Compounds)

Swissprot:
ACM4_RAT
Stitch:
ACM4_RAT
UniProt:
P08485
ChEMBL:
CHEMBL317
PDB:
Chrm4

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 174 15 12 12
Binding ≤ 1μM 93 9 8 9
Functional ≤ 10μM 9 6 4 3

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 536 44 30 27
ACM4_MOUSE P32211 CHEMBL4572 Muscarinic Acetylcholine Receptor M4, Mouse 4 4 4 4
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 922 63 32 32
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 661 53 31 35
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 336 22 18 17
ACM5_RAT P08911 CHEMBL277 Muscarinic Acetylcholine Receptor M5, Rat 48 3 3 3

Clustered By Gene (0)

Clustered By Organism (5)

Code Description Substances Purchasable Natural In Man
ACM4-1-E Muscarinic Acetylcholine Receptor M4 (cluster #1 Of 6), Eukaryotic 353 35 21 23
ACM4-2-E Muscarinic Acetylcholine Receptor M4 (cluster #2 Of 6), Eukaryotic 16 6 6 5
ACM4-3-E Muscarinic Acetylcholine Receptor M4 (cluster #3 Of 6), Eukaryotic 142 9 4 6
ACM4-4-E Muscarinic Acetylcholine Receptor M4 (cluster #4 Of 6), Eukaryotic 10 2 1 0
ACM4-5-E Muscarinic Acetylcholine Receptor M4 (cluster #5 Of 6), Eukaryotic 34 1 3 0
ACM4-6-E Muscarinic Acetylcholine Receptor M4 (cluster #6 Of 6), Eukaryotic 161 2 3 2
Uniprot Swissprot Chembl Description Number Shared
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 169
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 149
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 140
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 46
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 14
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 14
ACM1_MOUSE P12657 CHEMBL3733 Muscarinic Acetylcholine Receptor M1, Mouse 13
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 11
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 9
Z104290 Z104290 CHEMBL1907596 Neuronal Acetylcholine Receptor; Alpha4/beta2 8
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 6
ACM2_MOUSE Q9ERZ4 CHEMBL3197 Muscarinic Acetylcholine Receptor M2, Mouse 3
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 2
ACES_MOUSE P21836 CHEMBL3198 Acetylcholinesterase, Mouse 2
ACM3_MOUSE Q9ERZ3 CHEMBL5105 Muscarinic Acetylcholine Receptor M3, Mouse 2
ACM4_MOUSE P32211 CHEMBL4572 Muscarinic Acetylcholine Receptor M4, Mouse 2
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 1
5HT1A_MOUSE Q64264 CHEMBL3737 Serotonin 1a (5-HT1a) Receptor, Mouse 1
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 1
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 1
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 1
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 1
5HT2A_BOVIN Q75Z89 CHEMBL3446 Serotonin 2a (5-HT2a) Receptor, Bovin 1
5HT2A_HUMAN P28223 CHEMBL224 Serotonin 2a (5-HT2a) Receptor, Human 1
5HT2A_MOUSE P35363 CHEMBL5377 Serotonin 2a (5-HT2a) Receptor, Mouse 1
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 1
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 1
5HT2B_MOUSE Q02152 CHEMBL2583 Serotonin 2b (5-HT2b) Receptor, Mouse 1
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 1
5HT2C_HUMAN P28335 CHEMBL225 Serotonin 2c (5-HT2c) Receptor, Human 1
5HT2C_MOUSE P34968 CHEMBL3006 Serotonin 2c (5-HT2c) Receptor, Mouse 1
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 1
5HT3A_MOUSE P23979 CHEMBL4972 Serotonin 3a (5-HT3a) Receptor, Mouse 1
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 1
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 1
5HT5A_HUMAN P47898 CHEMBL3426 Serotonin 5a (5-HT5a) Receptor, Human 1
5HT6R_HUMAN P50406 CHEMBL3371 Serotonin 6 (5-HT6) Receptor, Human 1
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 1
5HT7R_RAT P32305 CHEMBL3223 Serotonin 7 (5-HT7) Receptor, Rat 1
ACH10_RAT Q9JLB5 CHEMBL3461 Neuronal Acetylcholine Receptor Protein Alpha-10 Subunit, Rat 1
ACHA2_RAT P12389 CHEMBL2584 Neuronal Acetylcholine Receptor Protein Alpha-2 Subunit, Rat 1
ACHA3_RAT P04757 CHEMBL3818 Neuronal Acetylcholine Receptor Protein Alpha-3 Subunit, Rat 1
ACHA4_RAT P09483 CHEMBL307 Neuronal Acetylcholine Receptor Protein Alpha-4 Subunit, Rat 1
ACHB2_RAT P12390 CHEMBL3001 Neuronal Acetylcholine Receptor Protein Beta-2 Subunit, Rat 1
ACHB4_RAT P12392 CHEMBL2658 Neuronal Acetylcholine Receptor Protein Beta-4 Subunit, Rat 1
ACHD_TORCA P02718 CHEMBL3916 Acetylcholine Receptor Protein Delta Chain, Torca 1
ACM5_MOUSE Q920H4 CHEMBL2324 Muscarinic Acetylcholine Receptor M5, Mouse 1
ACM5_RAT P08911 CHEMBL277 Muscarinic Acetylcholine Receptor M5, Rat 1
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 1
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 1
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 1
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 1
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 1
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 1
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 1
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 1
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 1
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 1
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 1
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 1
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 1
DRD1_BOVIN Q95136 CHEMBL2967 Dopamine D1 Receptor, Bovin 1
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 1
DRD1_PIG P50130 CHEMBL5067 Dopamine D1 Receptor, Pig 1
DRD1_RAT P18901 CHEMBL265 Dopamine D1 Receptor, Rat 1
DRD2_BOVIN P20288 CHEMBL3998 Dopamine D2 Receptor, Bovin 1
DRD2_CHLAE P52702 CHEMBL5456 Dopamine D2 Receptor, Chlae 1
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 1
DRD2_MOUSE P61168 CHEMBL3427 Dopamine D2 Receptor, Mouse 1
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 1
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1
DRD3_RAT P19020 CHEMBL3138 Dopamine D3 Receptor, Rat 1
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 1
DRD4_RAT P30729 CHEMBL3361 Dopamine D4 Receptor, Rat 1
DRD5_HUMAN P21918 CHEMBL1850 Dopamine D5 Receptor, Human 1
DRD5_RAT P25115 CHEMBL2281 Dopamine D5 Receptor, Rat 1
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 1
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 1
HRH2_RAT P25102 CHEMBL4654 Histamine H2 Receptor, Rat 1
HRH3_RAT Q9QYN8 CHEMBL4124 Histamine H3 Receptor, Rat 1
HRH4_HUMAN Q9H3N8 CHEMBL3759 Histamine H4 Receptor, Human 1
HRH4_RAT Q91ZY1 CHEMBL4468 Histamine H4 Receptor, Rat 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
Q63380_RAT Q63380 CHEMBL6184 Transporter, Rat 1
Q8WMX0_BOVIN Q8WMX0 CHEMBL2672 Muscarinic Acetylcholine Receptor M1, Bovin 1
Q9WTR4_RAT Q9WTR4 CHEMBL304 Norepinephrine Transporter, Rat 1
SC6A4_HUMAN P31645 CHEMBL228 Serotonin Transporter, Human 1
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 1
Z102306 Z102306 CHEMBL613606 Aorta 1
Z104281 Z104281 CHEMBL1907587 Neuronal Acetylcholine Receptor; Alpha3/beta2 1
Z104286 Z104286 CHEMBL1907592 Neuronal Acetylcholine Receptor; Alpha2/beta2 1
Z104287 Z104287 CHEMBL1907593 Neuronal Acetylcholine Receptor; Alpha3/beta4 1
Z104289 Z104289 CHEMBL1907595 Neuronal Acetylcholine Receptor; Alpha4/beta4 1
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 1
Z50512 Z50512 CHEMBL369 Cavia Porcellus 1
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1
Z80024 Z80024 CHEMBL614518 A9 (Fibroblast Cells) 1