UCSF

Muscarinic Acetylcholine Receptor M3, Mouse (4 Compounds)

Swissprot:
ACM3_MOUSE
Stitch:
ACM3_MOUSE
UniProt:
Q9ERZ3
ChEMBL:
CHEMBL5105
Reactome:
REACT_247495
REACT_207651
REACT_240390
PDB:
Chrm3

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 4 4 4 4
Binding ≤ 1μM 2 2 2 2
Functional ≤ 10μM 10 3 3 3

Reactome Network (3)

Reactome ID Description Species
REACT_247495 Acetylcholine regulates insulin secretion Mus musculus
REACT_207651 G alpha (q) signalling events Mus musculus
REACT_240390 Muscarinic acetylcholine receptors Mus musculus
Uniprot Swissprot Chembl Description Number Shared
ACM1_MOUSE P12657 CHEMBL3733 Muscarinic Acetylcholine Receptor M1, Mouse 8
ACM5_MOUSE Q920H4 CHEMBL2324 Muscarinic Acetylcholine Receptor M5, Mouse 4

Muscarinic acetylcholine receptors

Uniprot Swissprot Chembl Description Number Shared
ACM1_MOUSE P12657 CHEMBL3733 Muscarinic Acetylcholine Receptor M1, Mouse 8
ACM2_MOUSE Q9ERZ4 CHEMBL3197 Muscarinic Acetylcholine Receptor M2, Mouse 5
ACM4_MOUSE P32211 CHEMBL4572 Muscarinic Acetylcholine Receptor M4, Mouse 4
ACM5_MOUSE Q920H4 CHEMBL2324 Muscarinic Acetylcholine Receptor M5, Mouse 4
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 1,056 55 33 35
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 336 22 18 17
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
ACM1_MOUSE P12657 CHEMBL3733 Muscarinic Acetylcholine Receptor M1, Mouse 54 11 10 10
ACM2_MOUSE Q9ERZ4 CHEMBL3197 Muscarinic Acetylcholine Receptor M2, Mouse 23 7 7 7
ACM4_MOUSE P32211 CHEMBL4572 Muscarinic Acetylcholine Receptor M4, Mouse 4 4 4 4
ACM5_MOUSE Q920H4 CHEMBL2324 Muscarinic Acetylcholine Receptor M5, Mouse 4 4 4 4

Clustered By Gene (0)

Clustered By Organism (4)

Code Description Substances Purchasable Natural In Man
ACM3-1-E Muscarinic Acetylcholine Receptor M3 (cluster #1 Of 5), Eukaryotic 926 44 24 28
ACM3-2-E Muscarinic Acetylcholine Receptor M3 (cluster #2 Of 5), Eukaryotic 223 11 13 8
ACM3-3-E Muscarinic Acetylcholine Receptor M3 (cluster #3 Of 5), Eukaryotic 59 6 2 6
ACM3-4-E Muscarinic Acetylcholine Receptor M3 (cluster #4 Of 5), Eukaryotic 112 7 5 4
ACM3-5-E Muscarinic Acetylcholine Receptor M3 (cluster #5 Of 5), Eukaryotic 55 2 1 0
Uniprot Swissprot Chembl Description Number Shared
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 7
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 5
ACM3_HUMAN P20309 CHEMBL245 Muscarinic Acetylcholine Receptor M3, Human 5
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 5
ACM1_MOUSE P12657 CHEMBL3733 Muscarinic Acetylcholine Receptor M1, Mouse 4
ACM2_MOUSE Q9ERZ4 CHEMBL3197 Muscarinic Acetylcholine Receptor M2, Mouse 4
ACM4_MOUSE P32211 CHEMBL4572 Muscarinic Acetylcholine Receptor M4, Mouse 4
ACM5_MOUSE Q920H4 CHEMBL2324 Muscarinic Acetylcholine Receptor M5, Mouse 4
Z80024 Z80024 CHEMBL614518 A9 (Fibroblast Cells) 4
ACM4_HUMAN P08173 CHEMBL1821 Muscarinic Acetylcholine Receptor M4, Human 3
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 3
Z104303 Z104303 CHEMBL1907609 Muscarinic Acetylcholine Receptor 3
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 2
ACM3_RAT P08483 CHEMBL320 Muscarinic Acetylcholine Receptor M3, Rat 2
ACM4_RAT P08485 CHEMBL317 Muscarinic Acetylcholine Receptor M4, Rat 2
A2AIR5_MOUSE A2AIR5 CHEMBL2562 Glutamate [NMDA] Receptor Subunit 3A, Mouse 1
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 1
ACM2_RAT P10980 CHEMBL309 Muscarinic Acetylcholine Receptor M2, Rat 1
CHLE_MOUSE Q03311 CHEMBL2528 Butyrylcholinesterase, Mouse 1
NMD3A_HUMAN Q8TCU5 CHEMBL4787 Glutamate [NMDA] Receptor Subunit 3A, Human 1
NMD3B_HUMAN O60391 CHEMBL2913 Glutamate [NMDA] Receptor Subunit 3B, Human 1
NMD3B_MOUSE Q91ZU9 CHEMBL2557 Glutamate [NMDA] Receptor Subunit 3B, Mouse 1
NMDE1_HUMAN Q12879 CHEMBL1972 Glutamate [NMDA] Receptor Subunit Epsilon 1, Human 1
NMDE1_MOUSE P35436 CHEMBL2521 Glutamate [NMDA] Receptor Subunit Epsilon 1, Mouse 1
NMDE2_HUMAN Q13224 CHEMBL1904 Glutamate [NMDA] Receptor Subunit Epsilon 2, Human 1
NMDE2_MOUSE Q01097 CHEMBL3442 Glutamate [NMDA] Receptor Subunit Epsilon 2, Mouse 1
NMDE3_HUMAN Q14957 CHEMBL4109 Glutamate [NMDA] Receptor Subunit Epsilon 3, Human 1
NMDE3_MOUSE Q01098 CHEMBL3555 Glutamate [NMDA] Receptor Subunit Epsilon 3, Mouse 1
NMDE3_RAT Q00961 CHEMBL401 Glutamate [NMDA] Receptor Subunit Epsilon 3, Rat 1
NMDE4_HUMAN O15399 CHEMBL2591 Glutamate [NMDA] Receptor Subunit Epsilon 4, Human 1
NMDE4_MOUSE Q03391 CHEMBL2893 Glutamate [NMDA] Receptor Subunit Epsilon 4, Mouse 1
NMDZ1_HUMAN Q05586 CHEMBL2015 Glutamate (NMDA) Receptor Subunit Zeta 1, Human 1
NMDZ1_MOUSE P35438 CHEMBL2895 Glutamate (NMDA) Receptor Subunit Zeta 1, Mouse 1
NMDZ1_RAT P35439 CHEMBL330 Glutamate (NMDA) Receptor Subunit Zeta 1, Rat 1
PCP_HUMAN P42785 CHEMBL2335 Lysosomal Pro-X Carboxypeptidase, Human 1
Q8WMX0_BOVIN Q8WMX0 CHEMBL2672 Muscarinic Acetylcholine Receptor M1, Bovin 1
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 1
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 1
Z102306 Z102306 CHEMBL613606 Aorta 1
Z104302 Z104302 CHEMBL1907608 Glutamate NMDA Receptor 1
Z50512 Z50512 CHEMBL369 Cavia Porcellus 1
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 1
Z50594 Z50594 CHEMBL375 Mus Musculus 1