UCSF

Nociceptin Receptor, Human (1,215 Compounds)

Swissprot:
OPRX_HUMAN
Stitch:
OPRX_HUMAN
UniProt:
P41146
ChEMBL:
CHEMBL2014
Reactome:
REACT_19231
REACT_14819
PDB:
OPRL1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 1,215 19 5 6
Binding ≤ 1μM 1,109 17 5 5
Functional ≤ 10μM 167 1 0 0

Reactome Network (2)

Reactome ID Description Species
REACT_19231 G alpha (i) signalling events Homo sapiens
REACT_14819 Peptide ligand-binding receptors Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 3
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 1
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 5
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 7
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 4
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 385
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 540
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 870

Peptide ligand-binding receptors

Uniprot Swissprot Chembl Description Number Shared
GASR_HUMAN P32239 CHEMBL298 Cholecystokinin B Receptor, Human 1
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 385
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 540
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 870
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
OPRX_RAT P35370 CHEMBL4503 Nociceptin Receptor, Rat 45 2 1 2

Clustered By Gene (0)

Uniprot Swissprot Chembl Description Number Shared
OPRM_HUMAN P35372 CHEMBL233 Mu Opioid Receptor, Human 870
OPRK_HUMAN P41145 CHEMBL237 Kappa Opioid Receptor, Human 540
OPRD_HUMAN P41143 CHEMBL236 Delta Opioid Receptor, Human 385
OPRK_CAVPO P41144 CHEMBL3952 Kappa Opioid Receptor, Guinea Pig 48
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 39
OPRM_CAVPO P97266 CHEMBL4354 Mu Opioid Receptor, Guinea Pig 18
SC6A9_HUMAN P48067 CHEMBL2337 Glycine Transporter 1, Human 16
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 9
OPRD_RAT P33533 CHEMBL269 Delta Opioid Receptor, Rat 8
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 7
OPRK_RAT P34975 CHEMBL3614 Kappa Opioid Receptor, Rat 7
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 5
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 5
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 5
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 5
CAC1C_HUMAN Q13936 CHEMBL1940 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Human 4
CAC1D_HUMAN Q01668 CHEMBL4138 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Human 4
CAC1F_HUMAN O60840 CHEMBL5593 Voltage-gated L-type Calcium Channel Alpha-1F Subunit, Human 4
CAC1S_HUMAN Q13698 CHEMBL3805 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Human 4
DRD4_HUMAN P21917 CHEMBL219 Dopamine D4 Receptor, Human 4
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 4
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 3
ACM1_HUMAN P11229 CHEMBL216 Muscarinic Acetylcholine Receptor M1, Human 3
ACM2_HUMAN P08172 CHEMBL211 Muscarinic Acetylcholine Receptor M2, Human 3
OPRD_MOUSE P32300 CHEMBL3222 Delta Opioid Receptor, Mouse 3
OPRM_MOUSE P42866 CHEMBL2858 Mu Opioid Receptor, Mouse 3
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 3
CAC1S_RAT Q02485 CHEMBL4108 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Rat 2
OPRK_MOUSE P33534 CHEMBL4329 Kappa Opioid Receptor, Mouse 2
SC6A3_HUMAN Q01959 CHEMBL238 Dopamine Transporter, Human 2
Z104287 Z104287 CHEMBL1907593 Neuronal Acetylcholine Receptor; Alpha3/beta4 2
Z104290 Z104290 CHEMBL1907596 Neuronal Acetylcholine Receptor; Alpha4/beta2 2
Z50594 Z50594 CHEMBL375 Mus Musculus 2
5HT2B_HUMAN P41595 CHEMBL1833 Serotonin 2b (5-HT2b) Receptor, Human 1
ACM5_HUMAN P08912 CHEMBL2035 Muscarinic Acetylcholine Receptor M5, Human 1
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 1
ADRB1_HUMAN P08588 CHEMBL213 Beta-1 Adrenergic Receptor, Human 1
DRD1_HUMAN P21728 CHEMBL2056 Dopamine D1 Receptor, Human 1
GASR_HUMAN P32239 CHEMBL298 Cholecystokinin B Receptor, Human 1
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 1
OPRD_PIG P79291 CHEMBL4103 Delta Opioid Receptor, Pig 1
OPRM_BOVIN P79350 CHEMBL3041 Mu Opioid Receptor, Bovin 1
OPRX_RAT P35370 CHEMBL4503 Nociceptin Receptor, Rat 1
SC6A2_HUMAN P23975 CHEMBL222 Norepinephrine Transporter, Human 1
SC6A5_HUMAN Q9Y345 CHEMBL3060 Glycine Transporter 2, Human 1
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 1
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 1
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 1
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 1
SGMR1_MOUSE O55242 CHEMBL3465 Sigma Opioid Receptor, Mouse 1
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 1

Most Common Rings