UCSF

Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Rat (328 Compounds)

Swissprot:
CAC1D_RAT
Stitch:
CAC1D_RAT
UniProt:
P27732
ChEMBL:
CHEMBL4132
PDB:
Cacna1d

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 328 19 15 18
Binding ≤ 1μM 246 17 13 16
Functional ≤ 10μM 295 23 14 14

Reactome Network (0)

UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CAC1D_HUMAN Q01668 CHEMBL4138 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Human 66 13 6 7
CAC1D_MOUSE Q99246 CHEMBL3073 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Mouse 5 0 0 0

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
CAC1D-1-E Voltage-gated L-type Calcium Channel Alpha-1D Subunit (cluster #1 Of 2), Eukaryotic 336 25 19 23
CAC1D-2-E Voltage-gated L-type Calcium Channel Alpha-1D Subunit (cluster #2 Of 2), Eukaryotic 67 5 3 3
Uniprot Swissprot Chembl Description Number Shared
CAC1C_RAT P22002 CHEMBL3762 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat 400
CAC1S_RAT Q02485 CHEMBL4108 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Rat 284
CAC1C_RABIT P15381 CHEMBL2830 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rabit 129
CAC1E_RAT Q07652 CHEMBL4115 Voltage-gated R-type Calcium Channel Alpha-1E Subunit, Rat 114
CAC1B_HUMAN Q00975 CHEMBL4478 Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Human 49
Z80175 Z80175 CHEMBL614585 IMR-32 (Neuroblastoma Cells) 42
CAC1A_RAT P54282 CHEMBL4417 Voltage-gated P/Q-type Calcium Channel Alpha-1A Subunit, Rat 13
CAC1B_RAT Q02294 CHEMBL5107 Voltage-gated N-type Calcium Channel Alpha-1B Subunit, Rat 13
TSPO_RAT P16257 CHEMBL4552 Peripheral-type Benzodiazepine Receptor, Rat 13
AA3R_HUMAN P33765 CHEMBL256 Adenosine A3 Receptor, Human 11
CAC1G_RAT O54898 CHEMBL4257 Voltage-gated T-type Calcium Channel Alpha-1G Subunit, Rat 10
CAC1H_RAT Q9EQ60 CHEMBL5134 Voltage-gated T-type Calcium Channel Alpha-1H Subunit, Rat 10
CAC1I_RAT Q9Z0Y8 CHEMBL5459 Voltage-gated T-type Calcium Channel Alpha-1I Subunit, Rat 10
Z50597 Z50597 CHEMBL376 Rattus Norvegicus 10
ADA1A_HUMAN P35348 CHEMBL229 Alpha-1a Adrenergic Receptor, Human 7
ADA1D_HUMAN P25100 CHEMBL223 Alpha-1d Adrenergic Receptor, Human 7
AA1R_RAT P25099 CHEMBL318 Adenosine A1 Receptor, Rat 6
AA2AR_RAT P30543 CHEMBL302 Adenosine A2a Receptor, Rat 6
ADA1B_HUMAN P35368 CHEMBL232 Alpha-1b Adrenergic Receptor, Human 6
ADA2A_HUMAN P08913 CHEMBL1867 Alpha-2a Adrenergic Receptor, Human 6
ADA2B_HUMAN P18089 CHEMBL1942 Alpha-2b Adrenergic Receptor, Human 6
ADA2C_HUMAN P18825 CHEMBL1916 Alpha-2c Adrenergic Receptor, Human 6
SCN2A_HUMAN Q99250 CHEMBL4187 Sodium Channel Protein Type II Alpha Subunit, Human 6
ADA2B_RAT P19328 CHEMBL266 Alpha-2b Adrenergic Receptor, Rat 5
CAC1S_HUMAN Q13698 CHEMBL3805 Voltage-gated L-type Calcium Channel Alpha-1S Subunit, Human 5
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 5
Z50592 Z50592 CHEMBL374 Oryctolagus Cuniculus 5
ADA2A_RAT P22909 CHEMBL327 Alpha-2a Adrenergic Receptor, Rat 4
ADA2C_RAT P22086 CHEMBL314 Alpha-2c Adrenergic Receptor, Rat 4
Z104304 Z104304 CHEMBL1907610 Adrenergic Receptor Alpha-1 4
Z50425 Z50425 CHEMBL364 Plasmodium Falciparum 4
Z50466 Z50466 CHEMBL368 Trypanosoma Cruzi 4
5HT1B_RAT P28564 CHEMBL3459 Serotonin 1b (5-HT1b) Receptor, Rat 3
CAC1C_HUMAN Q13936 CHEMBL1940 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Human 3
CAC1D_HUMAN Q01668 CHEMBL4138 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Human 3
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 3
MDR1_MOUSE P06795 CHEMBL3467 P-glycoprotein 1, Mouse 3
MDR3_MOUSE P21447 CHEMBL2573 P-glycoprotein 3, Mouse 3
P97706_RAT P97706 CHEMBL4957 Sodium Channel Protein Type VI Alpha Subunit, Rat 3
SCN1A_HUMAN P35498 CHEMBL1845 Sodium Channel Protein Type I Alpha Subunit, Human 3
SCN3A_HUMAN Q9NY46 CHEMBL5163 Sodium Channel Protein Type III Alpha Subunit, Human 3
SCN5A_RAT P15389 CHEMBL3866 Sodium Channel Protein Type V Alpha Subunit, Rat 3
SCN8A_HUMAN Q9UQD0 CHEMBL5202 Sodium Channel Protein Type VIII Alpha Subunit, Human 3
TRPA1_MOUSE Q8BLA8 CHEMBL1075310 Transient Receptor Potential Cation Channel Subfamily A Member 1, Mouse 3
Z50512 Z50512 CHEMBL369 Cavia Porcellus 3
Z50590 Z50590 CHEMBL613488 Sus Scrofa 3
5HT2A_RAT P14842 CHEMBL322 Serotonin 2a (5-HT2a) Receptor, Rat 2
5HT2B_RAT P30994 CHEMBL323 Serotonin 2b (5-HT2b) Receptor, Rat 2
5HT2C_RAT P08909 CHEMBL324 Serotonin 2c (5-HT2c) Receptor, Rat 2
5HT3A_HUMAN P46098 CHEMBL1899 Serotonin 3a (5-HT3a) Receptor, Human 2
5HT3A_MOUSE P23979 CHEMBL4972 Serotonin 3a (5-HT3a) Receptor, Mouse 2
5HT3A_RAT P35563 CHEMBL2411 Serotonin 3a (5-HT3a) Receptor, Rat 2
5HT3B_HUMAN O95264 CHEMBL3895 Serotonin 3b (5-HT3b) Receptor, Human 2
5HT3B_MOUSE Q9JHJ5 CHEMBL3781 Serotonin 3b (5-HT3b) Receptor, Mouse 2
5HT3B_RAT Q9JJ16 CHEMBL3458 Serotonin 3b (5-HT3b) Receptor, Rat 2
5HT3C_HUMAN Q8WXA8 CHEMBL4795 Serotonin 3c (5-HT3c) Receptor, Human 2
5HT3D_HUMAN Q70Z44 CHEMBL4673 Serotonin 3d (5-HT3d) Receptor, Human 2
5HT3E_HUMAN A5X5Y0 CHEMBL3812 Serotonin 3e (5-HT3e) Receptor, Human 2
5HT4R_RAT Q62758 CHEMBL4317 Serotonin 4 (5-HT4) Receptor, Rat 2
ACM1_RAT P08482 CHEMBL276 Muscarinic Acetylcholine Receptor M1, Rat 2
ADA1A_BOVIN P18130 CHEMBL4892 Alpha-1a Adrenergic Receptor, Bovin 2
ADA1A_RAT P43140 CHEMBL319 Alpha-1a Adrenergic Receptor, Rat 2
ADA1B_RAT P15823 CHEMBL315 Alpha-1b Adrenergic Receptor, Rat 2
ADA1D_RAT P23944 CHEMBL326 Alpha-1d Adrenergic Receptor, Rat 2
CTRA_BOVIN P00766 CHEMBL3314 Alpha-chymotrypsin, Bovin 2
CYSP_TRYCR P25779 CHEMBL3563 Cruzipain, Trycr 2
DRD2_RAT P61169 CHEMBL339 Dopamine D2 Receptor, Rat 2
GASR_RAT P30553 CHEMBL3508 Cholecystokinin B Receptor, Rat 2
HRH1_RAT P31390 CHEMBL4701 Histamine H1 Receptor, Rat 2
MDHM_PIG P00346 CHEMBL3444 Malate Dehydrogenase Mitochondrial, Pig 2
OPRM_RAT P33535 CHEMBL270 Mu Opioid Receptor, Rat 2
S29A1_RAT O54698 CHEMBL4604 Equilibrative Nucleoside Transporter 1, Rat 2
SCN2A_RAT P04775 CHEMBL3399 Sodium Channel Protein Type II Alpha Subunit, Rat 2
SGMR1_RAT Q9R0C9 CHEMBL3602 Sigma Opioid Receptor, Rat 2
Z101865 Z101865 CHEMBL612790 Leishmania Chagasi 2
Z50457 Z50457 CHEMBL612877 Leishmania Amazonensis 2
Z50458 Z50458 CHEMBL612878 Leishmania Braziliensis 2
Z50460 Z50460 CHEMBL612879 Leishmania Major 2
5HT1A_HUMAN P08908 CHEMBL214 Serotonin 1a (5-HT1a) Receptor, Human 1
5HT1A_RAT P19327 CHEMBL273 Serotonin 1a (5-HT1a) Receptor, Rat 1
5HT1D_RAT P28565 CHEMBL5450 Serotonin 1d (5-HT1d) Receptor, Rat 1
5HT1F_RAT P30940 CHEMBL4646 Serotonin 1f (5-HT1f) Receptor, Rat 1
5HT7R_HUMAN P34969 CHEMBL3155 Serotonin 7 (5-HT7) Receptor, Human 1
CAC1F_HUMAN O60840 CHEMBL5593 Voltage-gated L-type Calcium Channel Alpha-1F Subunit, Human 1
DRD2_HUMAN P14416 CHEMBL217 Dopamine D2 Receptor, Human 1
DRD3_HUMAN P35462 CHEMBL234 Dopamine D3 Receptor, Human 1
EDNRA_PIG Q29010 CHEMBL4130 Endothelin Receptor ET-A, Pig 1
EDNRB_RAT P21451 CHEMBL4631 Endothelin Receptor ET-B, Rat 1
HRH1_HUMAN P35367 CHEMBL231 Histamine H1 Receptor, Human 1
KCNA5_HUMAN P22460 CHEMBL4306 Voltage-gated Potassium Channel Subunit Kv1.5, Human 1
MRP1_HUMAN P33527 CHEMBL3004 Multidrug Resistance-associated Protein 1, Human 1
S22A1_HUMAN O15245 CHEMBL5685 Solute Carrier Family 22 Member 1, Human 1
Z102306 Z102306 CHEMBL613606 Aorta 1
Z102372 Z102372 CHEMBL613672 Aorta 1
Z102380 Z102380 CHEMBL613680 Ileum 1
Z50740 Z50740 CHEMBL612361 Cricetinae Gen. Sp. 1
Z80051 Z80051 CHEMBL614532 C6-BU-1 1
Z80133 Z80133 CHEMBL614294 EMT6 (Mammary Carcinoma Cells) 1
Z80224 Z80224 CHEMBL387 MCF7 (Breast Carcinoma Cells) 1
Z80232 Z80232 CHEMBL614128 MCF7-VP 1
Z80362 Z80362 CHEMBL389 P388 (Lymphoma Cells) 1
Z80364 Z80364 CHEMBL614218 P388/ADR (Lymphoma Cells) 1
Z80532 Z80532 CHEMBL614774 T-24 (Bladder Carcinoma Cells) 1
Z80711 Z80711 CHEMBL613829 NCI/ADR-RES (Breast Carcinoma Cells) 1
Z80773 Z80773 CHEMBL614456 CHRC/5 Cell Line 1
Z80774 Z80774 CHEMBL614457 CHRC5 Cell Line 1
Z80928 Z80928 CHEMBL394 HCT-116 (Colon Carcinoma Cells) 1
Z81008 Z81008 CHEMBL614788 Human Breast Cancer Cell Lines 1
Z81245 Z81245 CHEMBL614697 MDA-MB-435 (Breast Carcinoma Cells) 1