UCSF

Cruzipain, Trycr (317 Compounds)

Swissprot:
CYSP_TRYCR
Stitch:
CYSP_TRYCR
UniProt:
P25779
ChEMBL:
CHEMBL3563
PDB:
1AIM (DOCK)
1EWL (DOCK)
1EWM (DOCK)
1EWO (DOCK)
1EWP (DOCK)
1F29 (DOCK)
1F2A (DOCK)
1F2B (DOCK)
1F2C (DOCK)
1ME3 (DOCK)
1ME4 (DOCK)
1U9Q (DOCK)
2AIM (DOCK)
2OZ2 (DOCK)
3HD3 (DOCK)
3I06 (DOCK)
3IUT (DOCK)
3KKU (DOCK)
3LXS (DOCK)

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 317 46 9 8
Binding ≤ 1μM 238 26 0 0

Reactome Network (0)

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
CYSP-1-E Cruzipain (cluster #1 Of 4), Eukaryotic 176 23 6 6
CYSP-2-E Cruzipain (cluster #2 Of 4), Eukaryotic 68 13 0 0
CYSP-3-E Cruzipain (cluster #3 Of 4), Eukaryotic 36 6 2 1
CYSP-4-E Cruzipain (cluster #4 Of 4), Eukaryotic 37 4 1 1
Uniprot Swissprot Chembl Description Number Shared
CATL1_HUMAN P07711 CHEMBL3837 Cathepsin L, Human 64
CATB_HUMAN P07858 CHEMBL4072 Cathepsin B, Human 44
Q95PM0_TRYBR Q95PM0 CHEMBL4188 Rhodesain, Trybr 34
CATS_HUMAN P25774 CHEMBL2954 Cathepsin S, Human 22
CATF_HUMAN Q9UBX1 CHEMBL2517 Cathepsin F, Human 21
CATK_HUMAN P43235 CHEMBL268 Cathepsin K, Human 17
Q9N6S8_PLAFA Q9N6S8 CHEMBL5800 Falcipain 2, Plafa 13
CATL2_HUMAN O60911 CHEMBL3272 Cathepsin L2, Human 6
CATZ_HUMAN Q9UBR2 CHEMBL4160 Cathepsin Z, Human 4
LMCPB_LEIME P36400 CHEMBL3821 Cysteine Proteinase B, Leime 4
PAPA1_CARPA P00784 CHEMBL4779 Papain, Carpa 4
CATC_HUMAN P53634 CHEMBL2252 Dipeptidyl Peptidase I, Human 3
CAC1C_RAT P22002 CHEMBL3762 Voltage-gated L-type Calcium Channel Alpha-1C Subunit, Rat 2
CAC1D_RAT P27732 CHEMBL4132 Voltage-gated L-type Calcium Channel Alpha-1D Subunit, Rat 2
CASP6_HUMAN P55212 CHEMBL3308 Caspase-6, Human 2
CATH_HUMAN P09668 CHEMBL2225 Cathepsin H, Human 2
CATL3_PARTE Q94715 CHEMBL4097 Cathepsin L2, Parte 2
CP51A_HUMAN Q16850 CHEMBL3849 Cytochrome P450 51, Human 2
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 2
Q4WNT5_ASPFU Q4WNT5 CHEMBL1681623 14-alpha Sterol Demethylase Cyp51A, Aspfu 2
Q96W81_ASPFM Q96W81 CHEMBL1681624 14-alpha Sterol Demethylase, Aspfm 2
TPA_HUMAN P00750 CHEMBL1873 Tissue-type Plasminogen Activator, Human 2
ABCG2_HUMAN Q9UNQ0 CHEMBL5393 ATP-binding Cassette Sub-family G Member 2, Human 1
CASP4_HUMAN P49662 CHEMBL2226 Caspase-4, Human 1
CASPE_HUMAN P31944 CHEMBL5991 Caspase-14, Human 1
CATB_RAT P00787 CHEMBL2602 Cathepsin B, Rat 1
CLTR1_HUMAN Q9Y271 CHEMBL1798 Cysteinyl Leukotriene Receptor 1, Human 1
CLTR2_HUMAN Q9NS75 CHEMBL4330 Cysteinyl Leukotriene Receptor 2, Human 1
EBP_HUMAN Q15125 CHEMBL4931 3-beta-hydroxysteroid-delta(8),delta(7)-isomerase, Human 1
ERG2_YEAST P32352 CHEMBL3224 C-8 Sterol Isomerase, Yeast 1
FDFT_HUMAN P37268 CHEMBL3338 Squalene Synthetase, Human 1
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 1
KLK4_HUMAN Q9Y5K2 CHEMBL4446 Kallikrein 4, Human 1
LEF_BACAN P15917 CHEMBL4372 Anthrax Lethal Factor, Bacan 1
MRP1_HUMAN P33527 CHEMBL3004 Multidrug Resistance-associated Protein 1, Human 1
MRP2_HUMAN Q92887 CHEMBL5748 Canalicular Multispecific Organic Anion Transporter 1, Human 1
MRP3_HUMAN O15438 CHEMBL5918 Canalicular Multispecific Organic Anion Transporter 2, Human 1
Q4U254_9ENTO Q4U254 CHEMBL2857 Human Rhinovirus A Protease, 9ento 1
Q6R7Z5_9TRYP Q6R7Z5 CHEMBL5832 Cathepsin B-like Cysteine Protease, 9tryp 1
SGMR1_HUMAN Q99720 CHEMBL287 Sigma Opioid Receptor, Human 1
THA_HUMAN P10827 CHEMBL1860 Thyroid Hormone Receptor Alpha, Human 1
THB_HUMAN P10828 CHEMBL1947 Thyroid Hormone Receptor Beta-1, Human 1

Most Common Rings