ZINC 12

User Information

Not Authenticated — sign in

Active cart: Temporary Cart (0 items)

Navigation

About
- ZINC
- BCIRC
- Irwin Lab
- Shoichet Lab
- UCSF
- Acknowledgements
- Facts
- Usage
Search
- By:
- Text
- Structure
- Properties
- Catalogs
- ZINC
- Targets
- Rings
- Combination
Subsets
- By:
- Catalog
- Property
- Target
- Ring
- Cart
Help
- Introduction
- FAQ
- Scripting/API
- Quick Search
- Problems
- Filtering
- History
Social
- ZINC Fans
- Decoy Club
- DOCK Fans
- Facebook
- Twitter
- Blog
- Linkedin
Quick Search ZINC ID or SMILES

Names
Compounds (713)
Reactome (2)
Related By:
Pathway (7)
Organism (1)
Gene (1)
Org. Clust. (0)
ChEMBL (27)
Rings (6)

Cysteinyl Leukotriene Receptor 1, Human (713 Compounds)

Swissprot:: CLTR1_HUMAN
Stitch:: CLTR1_HUMAN
UniProt:: Q9Y271
ChEMBL:: CHEMBL1798
Reactome:: REACT_18283; REACT_18302
PDB:: CYSLTR1

Compound Summary

Annotation Type	Substances	Purchasable	Natural	In Man
Binding ≤ 10μM	713	18	13	12
Binding ≤ 1μM	639	16	11	10
Functional ≤ 10μM	340	10	6	5

Reactome ID	Description	Species
REACT_18283	G alpha (q) signalling events	Homo sapiens
REACT_18302	Leukotriene receptors	Homo sapiens

Uniprot	Swissprot	Chembl	Description	Number Shared
CLTR2_HUMAN	Q9NS75	CHEMBL4330	Cysteinyl Leukotriene Receptor 2, Human	500
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	3
LT4R1_HUMAN	Q15722	CHEMBL3911	Leukotriene B4 Receptor 1, Human	2
LT4R2_HUMAN	Q9NPC1	CHEMBL3191	Leukotriene B4 Receptor 2, Human	2
PTAFR_HUMAN	P25105	CHEMBL250	Platelet Activating Factor Receptor, Human	3

Leukotriene receptors

Uniprot	Swissprot	Chembl	Description	Number Shared
CLTR2_HUMAN	Q9NS75	CHEMBL4330	Cysteinyl Leukotriene Receptor 2, Human	500
LT4R1_HUMAN	Q15722	CHEMBL3911	Leukotriene B4 Receptor 1, Human	2
LT4R2_HUMAN	Q9NPC1	CHEMBL3191	Leukotriene B4 Receptor 2, Human	2

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
CLTR1_CAVPO	Q2NNR5	CHEMBL5645	Cysteinyl Leukotriene Receptor 1, Guinea Pig	40	0	0	0

UniProt	Swissprot	ChEMBL	Description	Substances	Purchasable	Natural	In Man
CLTR2_HUMAN	Q9NS75	CHEMBL4330	Cysteinyl Leukotriene Receptor 2, Human	327	13	11	11

Clustered By Gene (0)

Uniprot	Swissprot	Chembl	Description	Number Shared
CLTR2_HUMAN	Q9NS75	CHEMBL4330	Cysteinyl Leukotriene Receptor 2, Human	500
Z50512	Z50512	CHEMBL369	Cavia Porcellus	48
Z50587	Z50587	CHEMBL372	Homo Sapiens	10
LOX5_RAT	P12527	CHEMBL312	Arachidonate 5-lipoxygenase, Rat	8
LOX5_HUMAN	P09917	CHEMBL215	Arachidonate 5-lipoxygenase, Human	4
THAS_HUMAN	P24557	CHEMBL1835	Thromboxane-A Synthase, Human	4
Z50597	Z50597	CHEMBL376	Rattus Norvegicus	4
Z80566	Z80566	CHEMBL612794	U-937 (Histiocytic Lymphoma Cells)	4
HRH1_HUMAN	P35367	CHEMBL231	Histamine H1 Receptor, Human	3
PTAFR_HUMAN	P25105	CHEMBL250	Platelet Activating Factor Receptor, Human	3
Z50425	Z50425	CHEMBL364	Plasmodium Falciparum	3
LT4R1_HUMAN	Q15722	CHEMBL3911	Leukotriene B4 Receptor 1, Human	2
LT4R2_HUMAN	Q9NPC1	CHEMBL3191	Leukotriene B4 Receptor 2, Human	2
MRP1_HUMAN	P33527	CHEMBL3004	Multidrug Resistance-associated Protein 1, Human	2
MRP2_HUMAN	Q92887	CHEMBL5748	Canalicular Multispecific Organic Anion Transporter 1, Human	2
PGH1_HUMAN	P23219	CHEMBL221	Cyclooxygenase-1, Human	2
PGH1_RAT	Q63921	CHEMBL4042	Cyclooxygenase-1, Rat	2
PGH2_HUMAN	P35354	CHEMBL230	Cyclooxygenase-2, Human	2
PGH2_RAT	P35355	CHEMBL2977	Cyclooxygenase-2, Rat	2
Q864F1_PIG	Q864F1	CHEMBL3634	Phosphodiesterase 5, Pig	2
CYSP_TRYCR	P25779	CHEMBL3563	Cruzipain, Trycr	1
LX12L_RAT	Q02759	CHEMBL2741	Arachidonate 12-lipoxygenase, Rat	1
PDE4A_HUMAN	P27815	CHEMBL254	Phosphodiesterase 4A, Human	1
PDE4B_HUMAN	Q07343	CHEMBL275	Phosphodiesterase 4B, Human	1
PDE4C_HUMAN	Q08493	CHEMBL291	Phosphodiesterase 4C, Human	1
PDE4D_HUMAN	Q08499	CHEMBL288	Phosphodiesterase 4D, Human	1
PERM_HUMAN	P05164	CHEMBL2439	Myeloperoxidase, Human	1