UCSF

Cytochrome P450 51, Human (29 Compounds)

Swissprot:
CP51A_HUMAN
Stitch:
CP51A_HUMAN
UniProt:
Q16850
ChEMBL:
CHEMBL3849
Reactome:
REACT_147904
REACT_9405
REACT_13812
PDB:
3JUS (DOCK)
3JUV (DOCK)
3LD6 (DOCK)
CYP51A1

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 29 11 11 13
Binding ≤ 1μM 16 8 8 9

Reactome Network (3)

Reactome ID Description Species
REACT_147904 Activation of gene expression by SREBF (SREBP) Homo sapiens
REACT_9405 Cholesterol biosynthesis Homo sapiens
REACT_13812 Endogenous sterols Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
C11B1_HUMAN P15538 CHEMBL1908 Cytochrome P450 11B1, Human 2
C11B2_HUMAN P19099 CHEMBL2722 Cytochrome P450 11B2, Human 1
CP17A_HUMAN P05093 CHEMBL3522 Cytochrome P450 17A1, Human 9
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 5
CP21A_HUMAN P08686 CHEMBL2759 Cytochrome P450 21, Human 1
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
CP51A_RAT Q64654 CHEMBL4981 Cytochrome P450 51, Rat 14 2 3 2

Clustered By Gene (0)

Clustered By Organism (1)

Code Description Substances Purchasable Natural In Man
CP51A-1-E Cytochrome P450 51 (cluster #1 Of 2), Eukaryotic 31 12 13 13
CP51A-2-E Cytochrome P450 51 (cluster #2 Of 2), Eukaryotic 10 0 0 0
Uniprot Swissprot Chembl Description Number Shared
CP17A_HUMAN P05093 CHEMBL3522 Cytochrome P450 17A1, Human 9
AMPC_ECOLI P00811 CHEMBL2026 Beta-lactamase, Ecoli 5
CP19A_HUMAN P11511 CHEMBL1978 Cytochrome P450 19A1, Human 5
CP51_MYCTU P0A512 CHEMBL5090 Lanosterol 14-alpha Demethylase, Myctu 5
Q4WNT5_ASPFU Q4WNT5 CHEMBL1681623 14-alpha Sterol Demethylase Cyp51A, Aspfu 3
Q96W81_ASPFM Q96W81 CHEMBL1681624 14-alpha Sterol Demethylase, Aspfm 3
C11B1_HUMAN P15538 CHEMBL1908 Cytochrome P450 11B1, Human 2
CP19A_RAT P22443 CHEMBL3859 Cytochrome P450 19A1, Rat 2
CP51A_RAT Q64654 CHEMBL4981 Cytochrome P450 51, Rat 2
CYSP_TRYCR P25779 CHEMBL3563 Cruzipain, Trycr 2
KCNH2_HUMAN Q12809 CHEMBL240 HERG, Human 2
PYGL_HUMAN P06737 CHEMBL2568 Liver Glycogen Phosphorylase, Human 2
C11B1_BOVIN P15150 CHEMBL2927 Cytochrome P450 11B1, Bovin 1
C11B2_HUMAN P19099 CHEMBL2722 Cytochrome P450 11B2, Human 1
CP11A_RAT P14137 CHEMBL5246 Cytochrome P450 11A1, Rat 1
CP17A_RAT P11715 CHEMBL4430 Cytochrome P450 17A1, Rat 1
CP21A_HUMAN P08686 CHEMBL2759 Cytochrome P450 21, Human 1
CP24A_HUMAN Q07973 CHEMBL4521 Cytochrome P450 24A1, Human 1
CP3A4_HUMAN P08684 CHEMBL340 Cytochrome P450 3A4, Human 1
CP7A1_RAT P18125 CHEMBL2339 Cytochrome P450 7A1, Rat 1
GNRHR_RAT P30969 CHEMBL3066 Gonadotropin-releasing Hormone Receptor, Rat 1
KCNA3_HUMAN P22001 CHEMBL4633 Voltage-gated Potassium Channel Subunit Kv1.3, Human 1
KCNN4_HUMAN O15554 CHEMBL4305 Intermediate Conductance Calcium-activated Potassium Channel Protein 4, Human 1
MDHM_PIG P00346 CHEMBL3444 Malate Dehydrogenase Mitochondrial, Pig 1
MDR1_HUMAN P08183 CHEMBL4302 P-glycoprotein 1, Human 1
PYGM_HUMAN P11217 CHEMBL3526 Muscle Glycogen Phosphorylase, Human 1