UCSF

Muscle Glycogen Phosphorylase, Human (135 Compounds)

Swissprot:
PYGM_HUMAN
Stitch:
PYGM_HUMAN
UniProt:
P11217
ChEMBL:
CHEMBL3526
Reactome:
REACT_1008
PDB:
1Z8D (DOCK)
PYGM

Compound Summary

Annotation Type Substances Purchasable Natural In Man
Binding ≤ 10μM 135 4 1 11
Binding ≤ 1μM 105 3 1 3

Reactome Network (1)

Reactome ID Description Species
REACT_1008 Glycogen breakdown (glycogenolysis) Homo sapiens
Uniprot Swissprot Chembl Description Number Shared
PHKG1_HUMAN Q16816 CHEMBL4004 Phosphorylase Kinase Gamma Subunit 1, Human 1
PHKG2_HUMAN P15735 CHEMBL2349 Phosphorylase Kinase Gamma Subunit 2, Human 1
PYGB_HUMAN P11216 CHEMBL3856 Brain Glycogen Phosphorylase, Human 4
PYGL_HUMAN P06737 CHEMBL2568 Liver Glycogen Phosphorylase, Human 105
UniProt Swissprot ChEMBL Description Substances Purchasable Natural In Man
PYGM_RABIT P00489 CHEMBL4696 Glycogen Phosphorylase, Muscle Form, Rabit 84 8 3 3

Clustered By Gene (0)

Clustered By Organism (3)

Code Description Substances Purchasable Natural In Man
PYGM-1-E Muscle Glycogen Phosphorylase (cluster #1 Of 4), Eukaryotic 99 4 2 0
PYGM-2-E Muscle Glycogen Phosphorylase (cluster #2 Of 4), Eukaryotic 39 3 1 2
PYGM-3-E Muscle Glycogen Phosphorylase (cluster #3 Of 4), Eukaryotic 74 3 0 1
PYGM-4-E Muscle Glycogen Phosphorylase (cluster #4 Of 4), Eukaryotic 14 2 1 11
Uniprot Swissprot Chembl Description Number Shared
PYGL_HUMAN P06737 CHEMBL2568 Liver Glycogen Phosphorylase, Human 105
PYGL_RAT P09811 CHEMBL3239 Liver Glycogen Phosphorylase, Rat 9
PYGL_MOUSE Q9ET01 CHEMBL3008 Liver Glycogen Phosphorylase, Mouse 5
PYGB_HUMAN P11216 CHEMBL3856 Brain Glycogen Phosphorylase, Human 4
AAK1_HUMAN Q2M2I8 CHEMBL3830 Adaptor-associated Kinase, Human 1
AAPK1_HUMAN Q13131 CHEMBL4045 AMP-activated Protein Kinase, Alpha-1 Subunit, Human 1
ACVR1_HUMAN Q04771 CHEMBL5903 Activin Receptor Type-1, Human 1
ALK_HUMAN Q9UM73 CHEMBL4247 ALK Tyrosine Kinase Receptor, Human 1
AVR2B_HUMAN Q13705 CHEMBL5466 Activin Receptor Type-2B, Human 1
CCNA1_HUMAN P78396 CHEMBL3609 Cyclin A1, Human 1
CCNA2_HUMAN P20248 CHEMBL2582 Cyclin A2, Human 1
CCNB1_HUMAN P14635 CHEMBL2412 G2/mitotic-specific Cyclin B1, Human 1
CCNB2_HUMAN O95067 CHEMBL3723 G2/mitotic-specific Cyclin B2, Human 1
CCNB3_HUMAN Q8WWL7 CHEMBL3606 G2/mitotic-specific Cyclin B3, Human 1
CCNB_MARGL P15206 CHEMBL4260 G2/mitotic-specific Cyclin B, Margl 1
CCND1_HUMAN P24385 CHEMBL3610 G1/S-specific Cyclin D1, Human 1
CCND2_HUMAN P30279 CHEMBL3613 G1/S-specific Cyclin D2, Human 1
CCND3_HUMAN P30281 CHEMBL2422 G1/S-specific Cyclin D3, Human 1
CCNE1_HUMAN P24864 CHEMBL3617 G1/S-specific Cyclin E1, Human 1
CCNE2_HUMAN O96020 CHEMBL2884 G1/S-specific Cyclin E2, Human 1
CCNH_HUMAN P51946 CHEMBL2165 Cyclin H, Human 1
CDK14_HUMAN O94921 CHEMBL6162 Serine/threonine-protein Kinase PFTAIRE-1, Human 1
CDK16_HUMAN Q00536 CHEMBL4597 Serine/threonine-protein Kinase PCTAIRE-1, Human 1
CDK17_HUMAN Q00537 CHEMBL5790 Serine/threonine-protein Kinase PCTAIRE-2, Human 1
CDK18_HUMAN Q07002 CHEMBL5316 Serine/threonine-protein Kinase PCTAIRE-3, Human 1
CDK19_HUMAN Q9BWU1 CHEMBL6002 Cell Division Cycle 2-like Protein Kinase 6, Human 1
CDK1_HUMAN P06493 CHEMBL308 Cyclin-dependent Kinase 1, Human 1
CDK2_HUMAN P24941 CHEMBL301 Cyclin-dependent Kinase 2, Human 1
CDK3_HUMAN Q00526 CHEMBL4442 Cyclin-dependent Kinase 3, Human 1
CDK4_HUMAN P11802 CHEMBL331 Cyclin-dependent Kinase 4, Human 1
CDK5_HUMAN Q00535 CHEMBL4036 Cyclin-dependent Kinase 5, Human 1
CDK6_HUMAN Q00534 CHEMBL2508 Cyclin-dependent Kinase 6, Human 1
CDK7_HUMAN P50613 CHEMBL3055 Cyclin-dependent Kinase 7, Human 1
CDK8_HUMAN P49336 CHEMBL5719 Cell Division Protein Kinase 8, Human 1
CDK9_HUMAN P50750 CHEMBL3116 Cyclin-dependent Kinase 9, Human 1
CLK1_HUMAN P49759 CHEMBL4224 Dual Specificty Protein Kinase CLK1, Human 1
CLK2_HUMAN P49760 CHEMBL4225 Dual Specificity Protein Kinase CLK2, Human 1
CLK3_HUMAN P49761 CHEMBL4226 Dual Specificity Protein Kinase CLK3, Human 1
CP51A_HUMAN Q16850 CHEMBL3849 Cytochrome P450 51, Human 1
CSF1R_HUMAN P07333 CHEMBL1844 Macrophage Colony Stimulating Factor Receptor, Human 1
CTRO_HUMAN O14578 CHEMBL5579 Citron Rho-interacting Kinase, Human 1
DCLK1_HUMAN O15075 CHEMBL5683 Serine/threonine-protein Kinase DCLK1, Human 1
DCLK3_HUMAN Q9C098 CHEMBL6123 Serine/threonine-protein Kinase DCLK3, Human 1
DMPK_HUMAN Q09013 CHEMBL5320 Myotonin-protein Kinase, Human 1
DYR1B_HUMAN Q9Y463 CHEMBL5543 Dual Specificity Tyrosine-phosphorylation-regulated Kinase 1B, Human 1
E2AK2_HUMAN P19525 CHEMBL5785 Interferon-induced, Double-stranded RNA-activated Protein Kinase, Human 1
EGFR_HUMAN P00533 CHEMBL203 Epidermal Growth Factor Receptor ErbB1, Human 1
EPHA2_HUMAN P29317 CHEMBL2068 Ephrin Type-A Receptor 2, Human 1
EPHA3_HUMAN P29320 CHEMBL4954 Ephrin Type-A Receptor 3, Human 1
EPHA5_HUMAN P54756 CHEMBL3987 Ephrin Type-A Receptor 5, Human 1
EPHB1_HUMAN P54762 CHEMBL5072 Ephrin Type-B Receptor 1, Human 1
FLT3_HUMAN P36888 CHEMBL1974 Tyrosine-protein Kinase Receptor FLT3, Human 1
GAK_HUMAN O14976 CHEMBL4355 Serine/threonine-protein Kinase GAK, Human 1
GSK3A_HUMAN P49840 CHEMBL2850 Glycogen Synthase Kinase-3 Alpha, Human 1
GSK3B_HUMAN P49841 CHEMBL262 Glycogen Synthase Kinase-3 Beta, Human 1
IKKE_HUMAN Q14164 CHEMBL3529 Inhibitor Of Nuclear Factor Kappa B Kinase Epsilon Subunit, Human 1
KCC2A_HUMAN Q9UQM7 CHEMBL4147 CaM Kinase II Alpha, Human 1
KCC2B_HUMAN Q13554 CHEMBL4121 CaM Kinase II Beta, Human 1
KCC4_HUMAN Q16566 CHEMBL2494 CaM Kinase IV, Human 1
KIT_HUMAN P10721 CHEMBL1936 Stem Cell Growth Factor Receptor, Human 1
KKCC1_HUMAN Q8N5S9 CHEMBL5256 CaM-kinase Kinase Alpha, Human 1
KKCC2_HUMAN Q96RR4 CHEMBL5284 CaM-kinase Kinase Beta, Human 1
KPCA_HUMAN P17252 CHEMBL299 Protein Kinase C Alpha, Human 1
KPCB_HUMAN P05771 CHEMBL3045 Protein Kinase C Beta, Human 1
KPCD1_HUMAN Q15139 CHEMBL3863 Protein Kinase C Mu, Human 1
KPCD2_HUMAN Q9BZL6 CHEMBL4900 Serine/threonine-protein Kinase D2, Human 1
KPCD3_HUMAN O94806 CHEMBL2595 Protein Kinase C Nu, Human 1
KPCD_HUMAN Q05655 CHEMBL2996 Protein Kinase C Delta, Human 1
KPCE_HUMAN Q02156 CHEMBL3582 Protein Kinase C Epsilon, Human 1
KPCG_HUMAN P05129 CHEMBL2938 Protein Kinase C Gamma, Human 1
KPCI_HUMAN P41743 CHEMBL2598 Protein Kinase C Iota, Human 1
KPCL_HUMAN P24723 CHEMBL3616 Protein Kinase C Eta, Human 1
KPCT_HUMAN Q04759 CHEMBL3920 Protein Kinase C Theta, Human 1
KPCZ_HUMAN Q05513 CHEMBL3438 Protein Kinase C Zeta, Human 1
KS6A1_HUMAN Q15418 CHEMBL2553 Ribosomal Protein S6 Kinase Alpha 1, Human 1
KS6A2_HUMAN Q15349 CHEMBL3906 Ribosomal Protein S6 Kinase Alpha 2, Human 1
KS6A4_HUMAN O75676 CHEMBL3125 Ribosomal Protein S6 Kinase Alpha 4, Human 1
KS6A5_HUMAN O75582 CHEMBL4237 Ribosomal Protein S6 Kinase Alpha 5, Human 1
KS6A6_HUMAN Q9UK32 CHEMBL4924 Ribosomal Protein S6 Kinase Alpha 6, Human 1
LTK_HUMAN P29376 CHEMBL5627 Leukocyte Tyrosine Kinase Receptor, Human 1
M3K10_HUMAN Q02779 CHEMBL2873 Mitogen-activated Protein Kinase Kinase Kinase 10, Human 1
M3K9_HUMAN P80192 CHEMBL2872 Mitogen-activated Protein Kinase Kinase Kinase 9, Human 1
M4K1_HUMAN Q92918 CHEMBL5749 Mitogen-activated Protein Kinase Kinase Kinase Kinase 1, Human 1
M4K3_HUMAN Q8IVH8 CHEMBL5432 Mitogen-activated Protein Kinase Kinase Kinase Kinase 3, Human 1
MERTK_HUMAN Q12866 CHEMBL5331 Proto-oncogene Tyrosine-protein Kinase MER, Human 1
MK07_HUMAN Q13164 CHEMBL5332 Mitogen-activated Protein Kinase 7, Human 1
MK10_HUMAN P53779 CHEMBL2637 C-Jun N-terminal Kinase 3, Human 1
MK15_HUMAN Q8TD08 CHEMBL5198 Mitogen-activated Protein Kinase 15, Human 1
MKNK2_HUMAN Q9HBH9 CHEMBL4204 MAP Kinase Signal-integrating Kinase 2, Human 1
MRCKA_HUMAN Q5VT25 CHEMBL4516 Serine/threonine-protein Kinase MRCK-A, Human 1
MRCKB_HUMAN Q9Y5S2 CHEMBL5052 Serine/threonine-protein Kinase MRCK Beta, Human 1
NUAK2_HUMAN Q9H093 CHEMBL5698 NUAK Family SNF1-like Kinase 2, Human 1
PHKG1_HUMAN Q16816 CHEMBL4004 Phosphorylase Kinase Gamma Subunit 1, Human 1
PHKG2_HUMAN P15735 CHEMBL2349 Phosphorylase Kinase Gamma Subunit 2, Human 1
PIM1_HUMAN P11309 CHEMBL2147 Serine/threonine-protein Kinase PIM1, Human 1
PIM2_HUMAN Q9P1W9 CHEMBL4523 Serine/threonine-protein Kinase PIM2, Human 1
PIM3_HUMAN Q86V86 CHEMBL5407 Serine/threonine-protein Kinase PIM3, Human 1
PKN1_HUMAN Q16512 CHEMBL3384 Protein Kinase N1, Human 1
PLK4_HUMAN O00444 CHEMBL3788 Serine/threonine-protein Kinase PLK4, Human 1
PYGM_RABIT P00489 CHEMBL4696 Glycogen Phosphorylase, Muscle Form, Rabit 1
SRMS_HUMAN Q9H3Y6 CHEMBL5703 Tyrosine-protein Kinase Srms, Human 1
ST17B_HUMAN O94768 CHEMBL3980 Serine/threonine-protein Kinase 17B, Human 1
STK33_HUMAN Q9BYT3 CHEMBL6005 Serine/threonine-protein Kinase 33, Human 1
STK3_HUMAN Q13188 CHEMBL4708 Serine/threonine-protein Kinase MST2, Human 1
TGFR2_HUMAN P37173 CHEMBL4267 TGF-beta Receptor Type II, Human 1
TNI3K_HUMAN Q59H18 CHEMBL5260 Serine/threonine-protein Kinase TNNI3K, Human 1
UFO_HUMAN P30530 CHEMBL4895 Tyrosine-protein Kinase Receptor UFO, Human 1
Z104294 Z104294 CHEMBL1907600 Cyclin-dependent Kinase 5/CDK5 Activator 1 1
Z104295 Z104295 CHEMBL1907601 Cyclin-dependent Kinase 4/cyclin D1 1
Z104296 Z104296 CHEMBL1907602 Cyclin-dependent Kinase 1/cyclin B1 1